Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jasmin Quandt"'
Autor:
Alexander Muik, Jasmin Quandt, Bonny Gaby Lui, Maren Bacher, Sebastian Lutz, Maika Grünenthal, Aras Toker, Jessica Grosser, Orkun Ozhelvaci, Olga Blokhina, Svetlana Shpyro, Isabel Vogler, Nadine Salisch, Özlem Türeci, Ugur Sahin
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114567- (2024)
Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure histories become increasingly complex through original and variant-adapted vaccines and infections with viral variants. Upon exposure to the highly altered Omicron spike g
Externí odkaz:
https://doaj.org/article/6d3ec055e6634edda15eec6aea826f60
Autor:
Alexander Muik, Bonny Gaby Lui, Jasmin Quandt, Huitian Diao, Yunguan Fu, Maren Bacher, Jessica Gordon, Aras Toker, Jessica Grosser, Orkun Ozhelvaci, Katharina Grikscheit, Sebastian Hoehl, Niko Kohmer, Yaniv Lustig, Gili Regev-Yochay, Sandra Ciesek, Karim Beguir, Asaf Poran, Isabel Vogler, Özlem Türeci, Ugur Sahin
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112888- (2023)
Summary: Evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has led to the emergence of sublineages with different patterns of neutralizing antibody evasion. We report that Omicron BA.4/BA.5 breakthrough inf
Externí odkaz:
https://doaj.org/article/9beefa8d290946d3b470f10ccdbe5236
Autor:
Jasmin Quandt, Christoph Schlude, Michael Bartoschek, Rainer Will, Angel Cid-Arregui, Sebastian Schölch, Christoph Reissfelder, Jürgen Weitz, Martin Schneider, Stefan Wiemann, Frank Momburg, Philipp Beckhove
Publikováno v:
OncoImmunology, Vol 7, Iss 12 (2018)
Mutated proteins arising from somatic mutations in tumors are promising targets for cancer immunotherapy. They represent true tumor-specific antigens (TSAs) as they are exclusively expressed in tumors, reduce the risk of autoimmunity and are more lik
Externí odkaz:
https://doaj.org/article/ab764d5d48cf413a95e4eba99888777a
Autor:
John L. Perez, Isabel Vogler, Evelyna Derhovanessian, Gábor Boros, David A. Cooper, Camila R. Fontes-Garfias, Kristen E. Pascal, Armin Schultz, Alexander Muik, Martin Bexon, Pei Yong Shi, Peter Koch, Ann Kathrin Eller, Verena Lörks, Mark Cutler, Daniel Maurus, Ludwig Heesen, Philip R. Dormitzer, Ugur Sahin, Kathrin U. Jansen, Manuel Tonigold, Jan Grützner, Azita J. Mahiny, Corinna Rosenbaum, Stefanie Bolte, Mathias Vormehr, Marie Cristine Kühnle, Sybille Baumann, Asaf Poran, Alexander Ulges, Alexandra Kemmer-Brück, Christos A. Kyratsous, Dirk Becker, Özlem Türeci, Alina Baum, Sebastian Brachtendorf, Lena M. Kranz, Carsten Boesler, Rolf Hilker, Tania Palanche, Julian Sikorski, Nicole Bidmon, Ulrich Luxemburger, David J. Langer, Jesse Z. Dong, Gábor Szabó, Jasmin Quandt, Katalin Karikó, Jonas Reinholz
Publikováno v:
Nature. 595:572-577
BNT162b2, a lipid nanoparticle (LNP) formulated nucleoside-modified messenger RNA (mRNA) that encodes the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike glycoprotein (S) stabilized in the prefusion conformation, has demonstrated 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0154147b441b18af735efb00657c62f
https://doi.org/10.1038/s41586-021-03653-6
https://doi.org/10.1038/s41586-021-03653-6
Autor:
Samuel B. Morin, Khashayarsha Khazaie, Christopher R. Weber, Joel Pekow, Randy F. Sweis, Azam Mohsin, Abu Osman, Michael K. Okoreeh, Manisha Krishnan, Stephen Arnovitz, Janine Woehlk, Fotini Gounari, Leila Haghi, Akinola Olumide Emmanuel, Alexander T. Pearson, Jasmin Quandt, Priya S. Mathur
Publikováno v:
Nature Immunology. 22:471-484
The diversity of regulatory T (Treg) cells in health and in disease remains unclear. Individuals with colorectal cancer harbor a subpopulation of RORγt+ Treg cells with elevated expression of β-catenin and pro-inflammatory properties. Here we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed50cbaca6d035714f9b91467731bb4f
https://doi.org/10.1038/s41590-021-00889-2
https://doi.org/10.1038/s41590-021-00889-2
Autor:
Jasmin Quandt, Alexander Muik, Nadine Salisch, Bonny Gaby Lui, Sebastian Lutz, Kimberly Krüger, Ann-Kathrin Wallisch, Petra Adams-Quack, Maren Bacher, Andrew Finlayson, Orkun Ozhelvaci, Isabel Vogler, Katharina Grikscheit, Sebastian Hoehl, Udo Goetsch, Sandra Ciesek, Özlem Türeci, Ugur Sahin
Omicron is the evolutionarily most distinct SARS-CoV-2 variant (VOC) to date and displays multiple amino acid alterations located in neutralizing antibody sites of the spike (S) protein. We report here that Omicron breakthrough infection in BNT162b2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73a19ad1c503597544d052a09aa83566
https://doi.org/10.1101/2022.04.01.486695
https://doi.org/10.1101/2022.04.01.486695
Autor:
Rolf Hilker, Jasmin Quandt, Boris Fischer, Jan Grützner, Kena A. Swanson, Sebastian Brachtendorf, Julian Sikorski, Mark Cutler, Kristen E. Pascal, Alexandra Kemmer-Brück, Lena M. Kranz, Dirk Becker, Katalin Karikó, Philip R. Dormitzer, Corinna Rosenbaum, Ulrich Luxemburger, Tania Palanche, Ugur Sahin, Camila R. Fontes-Garfias, Özlem Türeci, David A. Cooper, Armin Schultz, Alexander Muik, Ingrid L. Scully, Marie Cristine Kühnle, Jakob Loschko, Pei Yong Shi, Warren Kalina, Daniel Maurus, Verena Lörks, David J. Langer, Stefanie Bolte, Isabel Vogler, Mathias Vormehr, Christos A. Kyratsous, Carsten Boesler, Ann Kathrin Eller, Martin Bexon, Alina Baum, John L. Perez, Kathrin U. Jansen, Evelyna Derhovanessian
Publikováno v:
Nature
An effective vaccine is needed to halt the spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic. Recently, we reported safety, tolerability and antibody response data from an ongoing placebo-controlled, observer-blinded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e759c17cfd365c57e05fc7d355e9a4f
https://doi.org/10.1038/s41586-020-2814-7
https://doi.org/10.1038/s41586-020-2814-7
Autor:
Warren Kalina, Evelyna Derhovanessian, David J. Langer, Alexander Muik, Jakob Loschko, Kristen E. Pascal, Daniel Maurus, Corinna Rosenbaum, Katalin Karikó, Mark Cutler, Stefanie Bolte, Armin Schultz, Christos A. Kyratsous, Isabel Vogler, Ingrid L. Scully, Ann Kathrin Eller, Dirk Becker, David A. Cooper, Jan Grützner, Pei Yong Shi, Julian Sikorski, Tania Palanche, Martin Bexon, Alexandra Kemmer-Brück, Rolf Hilker, Ulrich Luxemburger, Kathrin U. Jansen, Mathias Vormehr, Philip R. Dormitzer, Verena Lörks, Sebastian Brachtendorf, Lena M. Kranz, John L. Perez, Marie Cristine Kühnle, Jasmin Quandt, Boris Fischer, Kena A. Swanson, Özlem Türeci, Ugur Sahin, Camila R. Fontes-Garfias, Carsten Boesler, Alina Baum
Publikováno v:
Nature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a440c230522e2d8f68ee1727420d6386
Autor:
Khashayarsha Khazaie, Abu Osman, Bingyu Yan, Ying Li, Kevin Pavelko, Jasmin Quandt, Abdulrahman Saadalla, Mahendra Rathore, Majid Kazemian, Fotini Gounari
TCF1 is essential for the development and function of T regulatory cells (Tregs). However, how TCF1 regulates Treg function in homeostasis or under pathogenic conditions is poorly understood. Here, we ablated TCF1 in Tregs to elucidate its role in Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b162f84944dc3d67bf9404417b3f6fb
https://doi.org/10.21203/rs.3.rs-136816/v1
https://doi.org/10.21203/rs.3.rs-136816/v1
Autor:
Samuel B. Morin, Priya S. Mathur, Randy F. Sweis, Azam Moshin, Abu Osman, Manisha Krishnan, Fotini Gounari, Alexander T. Pearson, Michael K. Okoreeh, Jasmin Quandt, Khashayarsha Khazaie, Akinola Olumide Emmanuel, Janine Woehlk, Joel Pekow, Stephen Arnovitz, Christopher R. Weber, Leila Haghi
The molecular and functional diversity of regulatory T-cells (Tregs) in health and in disease remains unclear. We previously described in colorectal cancer (CRC) patients a subpopulation of RORγt+ Tregs with elevated expression of β-catenin and pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e067076338e0f2e732d2b33434bc221
https://doi.org/10.21203/rs.3.rs-110212/v1
https://doi.org/10.21203/rs.3.rs-110212/v1