Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jasmin Otten"'
Autor:
Nils Hansen-Algenstaedt, Ina Fuhrhop, Wolfgang Rüther, Lennart Viezens, Malte Schroeder, Jasmin Otten, Christian Schaefer, Walter Fiedler
Publikováno v:
Journal of Orthopaedic Research. 29:1251-1258
The systemic balance of angiogenic and anti-angiogenic factors has been proposed to play a key-role in primary tumor growth dependent growth suppression of secondary tumors. Despite the importance of the organ microenvironment to angiogenesis and mic
Autor:
Ina Fuhrhop, Wolfgang Rüther, Nils Hansen-Algenstaedt, Lennart Viezens, Christian Schaefer, Walter Fiedler, Malte Schroeder, Jasmin Otten
Publikováno v:
Journal of Orthopaedic Research. 28:1515-1521
Microcirculatory properties of tumors play a pivotal role in tumor progression and inefficacy of therapies. It has been hypothesized that surgical interventions result in an accelerated tumor growth by increasing the level of pro-angiogenic cytokines
Publikováno v:
Journal of Oncology, Vol 2010 (2010)
Journal of Oncology
Journal of Oncology
The TGF-beta pathway controls a broad range of cellular behavior including cell proliferation, differentiation, and apoptosis of various cell types including tumor cells, endothelial cells, immune cells, and fibroblasts. Besides TGF-beta's direct eff
Autor:
Sebastian Decker, Andrea Kristina Horst, Alexander Schultze, Walter Fiedler, Sonja Loges, Gunter Schuch, Carsten Bokemeyer, Gabi Vohwinkel, Jasmin Otten
Publikováno v:
Investigational New Drugs. 28:825-833
Neoangiogenesis plays an important role in tumor growth and metastasis. Evaluation of new anti-angiogenic targets may broaden the armament for future therapeutic concepts. Focal adhesion kinase (FAK), expressed in endothelial and tumor cells, is esse
Autor:
Alexander Schultze, Judith Dierlamm, Philippe Schafhausen, Carsten Bokemeyer, Walter Fiedler, Sonja Loges, Jasmin Otten, Tim H. Brümmendorf, Svenja Otterstetter
Publikováno v:
British Journal of Haematology. 142:115-118
The existence of adult haemangioblasts with dual haematopoietic and endothelial developmental potential was confirmed after detection of Ph(+) vascular endothelial cells in chronic myeloid leukaemia (CML) patients. Blood outgrowth endothelial cells (
Autor:
Jasmin Otten, Ronald Simon, Eik Vettorazzi, Guido Sauter, Alexander Schultze, Walter Fiedler, Lisa Schmitz, Jürgen Krauter, Carsten Bokemeyer, Andreas H. Marx, Sonja Loges
Publikováno v:
Leukemia. 25(2)
Expression of TGF-β receptor ALK-5 has a negative impact on outcome of patients with acute myeloid leukemia
Autor:
Christian, Schaefer, Malte, Schroeder, Ina, Fuhrhop, Lennart, Viezens, Jasmin, Otten, Walter, Fiedler, Wolfgang, Rüther, Nils, Hansen-Algenstaedt
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 29(8)
The systemic balance of angiogenic and anti-angiogenic factors has been proposed to play a key-role in primary tumor growth dependent growth suppression of secondary tumors. Despite the importance of the organ microenvironment to angiogenesis and mic
Autor:
Sonja Loges, Uta Fischer, Carsten Bokemeyer, Walter Fiedler, Dieter K. Hossfeld, Jasmin Otten, Michaela Schweizer, Martin Butzal, Gunter Schuch
Publikováno v:
Biochemical and biophysical research communications. 357(4)
Bone marrow derived hematopoietic stem cells can function as endothelial progenitor cells. They are recruited to malignant tumors and differentiate into endothelial cells. This mechanism of neovascularization termed vasculogenesis is distinct from pr
Autor:
Alexander Schultze, Walter Fiedler, Jasmin Otten, Jürgen Krauter, Eik Vettorazzi, Lisa Schmitz, Carsten Bokemeyer
Publikováno v:
Blood. 114:1604-1604
Abstract 1604 Poster Board I-630 Introduction Bone marrow neoangiogenesis plays an important role in acute myeloid leukaemia. TGF-β has been shown to be involved in angiogenesis. TGF-β receptors are comprised of class I, class II and accessory rece
Autor:
Jasmin Otten, Alexander Schultze, Svenja Otterstetter, Philippe Schafhausen, Judith Dierlamm, Sonja Loges, Walter Fiedler, Carsten Bokemeyer, Tim H. Brümmendorf
Publikováno v:
Journal of Clinical Oncology. 26:7062-7062
7062 Background: As main actors in the generation of new blood vessels, endothelial progenitor cells have been intensely investigated during the past years. The detection of Philadelphia chromosome...