Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jasmin M. Siegle"'
Autor:
Pedro P. Rocha, Jasmin M. Siegle, B. Aranda Orgilles, Z. Ying, M. Abbruzzese, Markus Schober, Slobodan Beronja, Jane A. Skok, Ana Sastre-Perona, Steven Hoang-Phou, Ioannis Aifantis
SummaryThe fate choice between stem cell self-renewal and differentiation is regulated by bistable transcriptional networks, which are balanced in homeostasis and imbalanced in tumors. Yet, how stem cells switch from self-renewal to differentiation r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::483cd9412504b1930438cc5ea64c2d12
https://doi.org/10.1101/2021.08.18.455699
https://doi.org/10.1101/2021.08.18.455699
Autor:
Elisabeth Paietta, Sandrine Poglio, Vanina Gabriela Da Ros, Jay P. Patel, Jeremy B. Samon, Thomas Trimarchi, Jasmin M. Siegle, Maria Dominguez, Kim De Keersmaecker, Jacob M. Rowe, Tien Huynh, Ross L. Levine, Patrik Asp, Zuojian Tang, Dolors Ferres-Marco, Michael Hadler, Adolfo A. Ferrando, Filippo Utro, Janis Racevskis, Françoise Pflumio, Aristotelis Tsirigos, Maria Sol Flaherty, Stuart M. Brown, Iannis Aifantis, Raul Rabadan, Panagiotis Ntziachristos, Jelena Nedjic, Isaura Rigo, Pieter Van Vlierberghe
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature medicine
instname
Nature medicine
T cell acute lymphoblastic leukemia (T-ALL) is an immature hematopoietic malignancy driven mainly by oncogenic activation of NOTCH1 signaling1. In this study we report the presence of loss-of-function mutations and deletions of the EZH2 and SUZ12 gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8784ab8a0eb31dd9c6940649a5e356
http://hdl.handle.net/10261/66875
http://hdl.handle.net/10261/66875
Autor:
Alice Basin, Aristotelis Tsirigos, Rachel Sennett, John A. Carucci, Ana Sastre-Perona, Yoshiya Yonekubo, Jasmin M. Siegle, Jessie A. Brown, Markus Schober, Michael Rendl
Publikováno v:
Nature communications
Although the principles that balance stem cell self-renewal and differentiation in normal tissue homeostasis are beginning to emerge, it is still unclear whether cancer cells with tumour initiating potential are similarly governed, or whether they ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e29b338f02530cec2fa58d9aa5fe213
http://europepmc.org/articles/PMC4207965
http://europepmc.org/articles/PMC4207965
