Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jasmin Kuhn"'
Publikováno v:
Viruses, Vol 13, Iss 5, p 800 (2021)
Viruses are infectious agents that hijack the host cell machinery in order to replicate and generate progeny. Viral infection is initiated by attachment to host cell receptors, and typical viral receptors are cell-surface-borne molecules such as prot
Externí odkaz:
https://doaj.org/article/ca696cdef5c2437f9fda93b54756f92a
Publikováno v:
Viruses, Vol 13, Iss 800, p 800 (2021)
Viruses
Viruses
Viruses are infectious agents that hijack the host cell machinery in order to replicate and generate progeny. Viral infection is initiated by attachment to host cell receptors, and typical viral receptors are cell-surface-borne molecules such as prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9575e6893e594da0b6f0b39527b161
https://www.mdpi.com/1999-4915/13/5/800
https://www.mdpi.com/1999-4915/13/5/800
Autor:
Ulrich Lächelt, Don C. Lamb, Lun Peng, Ernst Wagner, Yi Lin, Ana Krhac Levacic, Miriam Höhn, Jasmin Kuhn, Nader Al Danaf
Publikováno v:
Bioconjugate Chemistry
The programmable endonuclease activity and simple usage of CRISPR/Cas9 have revolutionized the field of genome editing. The binding of single guide RNA (sgRNA) by the Cas9 protein results in the formation of negatively charged ribonucleoprotein (RNP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c06f3862b8053531e208d08b82e80e9e
https://pubmed.ncbi.nlm.nih.gov/31967454
https://pubmed.ncbi.nlm.nih.gov/31967454
Autor:
Kaloian Koynov, Jennifer Schultze, Benjamin Weber, Jasmin Kuhn, Regina Holm, Ulrich Lächelt, David Schwiertz, Matthias Barz
Publikováno v:
Macromolecular Bioscience, 20(1), 1900152. WILEY-V C H VERLAG GMBH
RNA interference provides enormous potential for the treatment of several diseases, including cancer. Nevertheless, successful therapies based on siRNA require overcoming various challenges, such as poor pharmacokinetic characteristics of the small R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af957372e02aa78d10f6b1b6a774c4f2
https://pubmed.ncbi.nlm.nih.gov/31430057
https://pubmed.ncbi.nlm.nih.gov/31430057
Autor:
Ulrich Lächelt, Sarah Kern, Ernst Wagner, Jan Gorges, Jasmin Kuhn, Uli Kazmaier, Emanuele Baratti, Ines Truebenbach
Publikováno v:
Macromolecular bioscience. 17(10)
The conjugation of small molecule drugs to ligand containing carrier systems facilitates receptor targeted delivery. The folate receptor (FR) constitutes an ideal target for tumor selective therapy, being overexpressed on several tumor types. It can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27961ebe136d7d35f6fe53a36706937
https://pubmed.ncbi.nlm.nih.gov/28371444
https://pubmed.ncbi.nlm.nih.gov/28371444
Autor:
Samir El Andaloussi, Jasmin Kuhn, Ulrich Lächelt, Philipp M. Klein, Miriam Höhn, Don C. Lamb, Yoshitsugu Aoki, Joel Z. Nordin, Ernst Wagner, Nader Al Danaf, Dominik M. Loy, Taavi Lehto, Sören Reinhard
Publikováno v:
Advanced Functional Materials. 29:1906432
Phosphorodiamidate morpholino oligomers (PMOs) are oligonucleotide analogs that can be used for therapeutic modulation of pre‐mRNA splicing. Similar to other classes of nucleic acid‐based therapeutics, PMOs require delivery systems for efficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a476553803684714833db66c3ca1f2a
https://doi.org/10.1002/adfm.201906432
https://doi.org/10.1002/adfm.201906432
Publikováno v:
Plant Science. 176:223-231
In contrast to the ubiquitously present flavonoids, dihydrochalcones seem to be restricted to approx. 30 plant families. In apple (Malus domestica Borkh.), the dihydrochalcone phloridzin (phloretin 2′-O-glucoside) is dominant representing more than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::144e65d88282e623c3eedcc102650039
https://doi.org/10.1016/j.plantsci.2008.10.011
https://doi.org/10.1016/j.plantsci.2008.10.011