Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jasmin Grählert"'
Autor:
Jonas, Lötscher, Adrià-Arnau, Martí I Líndez, Nicole, Kirchhammer, Elisabetta, Cribioli, Greta Maria Paola, Giordano Attianese, Marcel P, Trefny, Markus, Lenz, Sacha I, Rothschild, Paolo, Strati, Marco, Künzli, Claudia, Lotter, Susanne H, Schenk, Philippe, Dehio, Jordan, Löliger, Ludivine, Litzler, David, Schreiner, Victoria, Koch, Nicolas, Page, Dahye, Lee, Jasmin, Grählert, Dmitry, Kuzmin, Anne-Valérie, Burgener, Doron, Merkler, Miklos, Pless, Maria L, Balmer, Walter, Reith, Jörg, Huwyler, Melita, Irving, Carolyn G, King, Alfred, Zippelius, Christoph, Hess
Publikováno v:
Cell. 185(4)
The relevance of extracellular magnesium in cellular immunity remains largely unknown. Here, we show that the co-stimulatory cell-surface molecule LFA-1 requires magnesium to adopt its active conformation on CD8
Autor:
Jonas Lötscher, Adrià-Arnau Martí i Líndez, Nicole Kirchhammer, Elisabetta Cribioli, Greta Maria Paola Giordano Attianese, Marcel P. Trefny, Markus Lenz, Sacha I. Rothschild, Paolo Strati, Marco Künzli, Claudia Lotter, Susanne H. Schenk, Philippe Dehio, Jordan Löliger, Ludivine Litzler, David Schreiner, Victoria Koch, Nicolas Page, Dahye Lee, Jasmin Grählert, Dmitry Kuzmin, Anne-Valérie Burgener, Doron Merkler, Miklos Pless, Maria L. Balmer, Walter Reith, Jörg Huwyler, Melita Irving, Carolyn G. King, Alfred Zippelius, Christoph Hess
Publikováno v:
Cell. 185:585-602.e29
The relevance of extracellular magnesium in cellular immunity remains largely unknown. Here, we show that the co-stimulatory cell-surface molecule LFA-1 requires magnesium to adopt its active conformation on CD8+ T��cells, thereby augmenting calc
Autor:
Marco Fischer, Gunhild Unterstab, Jasmin Grählert, Ursula Sauder, Rebekah Steiner, Glenn R. Bantug, Christoph Hess, Patrick Gubser, Gideon Hoenger, Leyla Develioglu, Anne-Valérie Burgener, Sarah Dimeloe, Maria L. Balmer
Publikováno v:
European Journal of Immunology. 48:1632-1643
The role of mitochondrial biogenesis during naive to effector differentiation of CD8+ T cells remains ill explored. In this study, we describe a critical role for early mitochondrial biogenesis in supporting cytokine production of nascent activated h
Autor:
Maria L, Balmer, Eric H, Ma, Andrew J, Thompson, Raja, Epple, Gunhild, Unterstab, Jonas, Lötscher, Philippe, Dehio, Christian M, Schürch, Jan D, Warncke, Gaëlle, Perrin, Anne-Kathrin, Woischnig, Jasmin, Grählert, Jordan, Löliger, Nadine, Assmann, Glenn R, Bantug, Olivier P, Schären, Nina, Khanna, Adrian, Egli, Lukas, Bubendorf, Katharina, Rentsch, Siegfried, Hapfelmeier, Russell G, Jones, Christoph, Hess
Publikováno v:
Cell metabolism. 32(3)
Serum acetate increases upon systemic infection. Acutely, assimilation of acetate expands the capacity of memory CD8
Autor:
Jonas Lötscher, Christoph Hess, Bojana Müller-Durovic, Rebekah Steiner, Olivier Bignucolo, Rebecca Higgins, David Sancho, Mike Recher, Bettina Burger, Gunhild Unterstab, Michel Enamorado, Alexander A. Navarini, Anne-Valérie Burgener, Ursula Sauder, Jasmin Grählert, Rolf Brücker, Glenn R. Bantug, Sarai Martínez-Cano, Eric H. Ma, Marco Geigges, Alexander Schmidt, Jordan Loeliger, Ingmar Heijnen, Robert Ivanek, Benedikt J. Meyer, Russell G. Jones, Sarah Dimeloe, Nathan Cantoni, Danielle Hunziker, Christian R Kahlert, Monika Ebnöther, Raja Epple, Adhideb Ghosh
Publikováno v:
Nature immunology. 20(10)
Whether screening the metabolic activity of immune cells facilitates discovery of molecular pathology remains unknown. Here we prospectively screened the extracellular acidification rate as a measure of glycolysis and the oxygen consumption rate as a
Autor:
Leyla Develioglu, Annaïse Jauch, Weldy V. Bonilla, Timo Glatter, Siegfried Hapfelmeier, Glenn R. Bantug, Andrew J. Macpherson, Anne-Valérie Burgener, Magdalena A. Krzyzaniak, Russell G. Jones, Sarah Dimeloe, Emma Slack, Simona P. Pfister, Eric H. Ma, Mike Recher, Jasmin Grählert, Philippe Dehio, Christoph Hess, Marco Fischer, Réka Belle, Carolyn G. King, Maria L. Balmer
Publikováno v:
Immunity
IMMUNITY
IMMUNITY
How systemic metabolic alterations during acute infections impact immune cell function remains poorly understood. We found that acetate accumulates in the serum within hours of systemic bacterial infections and that these increased acetate concentrat
Autor:
Jordan Löliger, Jonas Lötscher, Russell G. Jones, Anne-Kathrin Woischnig, Maria L. Balmer, Nina Khanna, Lukas Bubendorf, Adrian Egli, Nadine Assmann, Eric H. Ma, Jasmin Grählert, Jan D. Warncke, Olivier P. Schären, Andrew J. Thompson, Raja Epple, Katharina Rentsch, Gaëlle Perrin, Christian M. Schürch, Glenn R. Bantug, Gunhild Unterstab, Siegfried Hapfelmeier, Philippe Dehio, Christoph Hess
Publikováno v:
Cell Metabolism. 32:457-467.e5
Serum acetate increases upon systemic infection. Acutely, assimilation of acetate expands the capacity of memory CD8+ T cells to produce IFN-γ. Whether acetate modulates memory CD8+ T cell metabolism and function during pathogen re-encounter remains
Publikováno v:
Aging (Albany NY)
Natural killer cells lacking expression of CD56 (CD56neg NK cells) have been described in chronic HIV and hepatitis C virus infection. Features and functions of CD56neg NK cells in the context of latent infection with CMV and / or EBV with age are no
Autor:
Marco, Fischer, Glenn R, Bantug, Sarah, Dimeloe, Patrick M, Gubser, Anne-Valérie, Burgener, Jasmin, Grählert, Maria L, Balmer, Leyla, Develioglu, Rebekah, Steiner, Gunhild, Unterstab, Ursula, Sauder, Gideon, Hoenger, Christoph, Hess
Publikováno v:
European journal of immunology. 48(10)
The role of mitochondrial biogenesis during naïve to effector differentiation of CD8
Autor:
Karthiga, Santhana Kumar, Dimitra, Tripolitsioti, Min, Ma, Jasmin, Grählert, Katja B, Egli, Giulio, Fiaschetti, Tarek, Shalaby, Michael A, Grotzer, Martin, Baumgartner
Publikováno v:
SpringerPlus
Medulloblastoma (MB) comprises four molecularly and genetically distinct subgroups of embryonal brain tumors that develop in the cerebellum. MB mostly affects infants and children and is difficult to treat because of frequent dissemination of tumor c