Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jasmeet Singh, Khara"'
Autor:
Yanwen Li, John Spiropoulos, William Cooley, Jasmeet Singh Khara, Camilla A Gladstone, Masanori Asai, Janine T Bossé, Brian D Robertson, Sandra M Newton, Paul R Langford
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 1126-1137 (2018)
Animal models have long been used in tuberculosis research to understand disease pathogenesis and to evaluate novel vaccine candidates and anti-mycobacterial drugs. However, all have limitations and there is no single animal model which mimics all th
Externí odkaz:
https://doaj.org/article/c306fe42163242288d6b47432b362fc0
Autor:
Jasmeet Singh Khara, Biljana Mojsoska, Devika Mukherjee, Paul R. Langford, Brian D. Robertson, Håvard Jenssen, Pui Lai Rachel Ee, Sandra M. Newton
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Tuberculosis (TB) results in both morbidity and mortality on a global scale. With drug resistance on the increase, there is an urgent need to develop novel anti-mycobacterials. Thus, we assessed the anti-mycobacterial potency of three novel synthetic
Externí odkaz:
https://doaj.org/article/43915dd51ff64546a2611e187f08e700
Autor:
Masanori Asai, Yanwen Li, Jasmeet Singh Khara, Brian D. Robertson, Paul R. Langford, Sandra M. Newton
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Drug screening models have a vital role in the development of novel antimycobacterial agents which are urgently needed to tackle drug-resistant tuberculosis (TB). We recently established the larvae of the insect Galleria mellonella (greater wax moth)
Externí odkaz:
https://doaj.org/article/25d488c9df084770b2eda6894e8a791c
Autor:
Jasmeet Singh Khara, Sybil Obuobi, Ying Wang, Hilda Kai Lin Tay, Vanitha Selvarajan, Nhan Dai Thien Tram, Pui Lai Rachel Ee
Publikováno v:
Journal of Controlled Release. 313:120-130
There is growing interest in the development of nucleic acid nanostructures as smart functional materials for applications in drug delivery. Inspired by the diverse physical interactions that exist in nature, crosslinked DNA nanostructures can serve
Autor:
Janine T. Bossé, Jasmeet Singh Khara, Paul R. Langford, John Spiropoulos, Brian D. Robertson, William Cooley, Camilla A Gladstone, Yanwen Li, Sandra M. Newton, Masanori Asai
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 1126-1137 (2018)
Virulence
Virulence
Animal models have long been used in tuberculosis research to understand disease pathogenesis and to evaluate novel vaccine candidates and anti-mycobacterial drugs. However, all have limitations and there is no single animal model which mimics all th
Autor:
Pui Lai Rachel Ee, Paul R. Langford, Biljana Mojsoska, Håvard Jenssen, Brian D. Robertson, Sandra M. Newton, Jasmeet Singh Khara, Devika Mukherjee
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Tuberculosis (TB) results in both morbidity and mortality on a global scale. With drug resistance on the increase, there is an urgent need to develop novel anti-mycobacterials. Thus, we assessed the anti-mycobacterial potency of three novel synthetic
Autor:
Jasmeet Singh, Khara, Biljana, Mojsoska, Devika, Mukherjee, Paul R, Langford, Brian D, Robertson, Håvard, Jenssen, Pui Lai Rachel, Ee, Sandra M, Newton
Publikováno v:
Frontiers in Microbiology
Tuberculosis (TB) results in both morbidity and mortality on a global scale. With drug resistance on the increase, there is an urgent need to develop novel anti-mycobacterials. Thus, we assessed the anti-mycobacterial potency of three novel synthetic
Autor:
Masanori, Asai, Yanwen, Li, Jasmeet Singh, Khara, Camilla A, Gladstone, Brian D, Robertson, Paul R, Langford, Sandra M, Newton
Publikováno v:
Journal of visualized experiments : JoVE. (148)
Tuberculosis is the leading global cause of infectious disease mortality and roughly a quarter of the world's population is believed to be infected with Mycobacterium tuberculosis. Despite decades of research, many of the mechanisms behind the succes
Autor:
Jasmeet Singh Khara, Yanwen Li, Brian D. Robertson, Masanori Asai, Sandra M. Newton, Paul R. Langford
Publikováno v:
Access Microbiology. 1
Animal infection models are vital as drug screens for novel therapeutics to tackle the global tuberculosis (TB) epidemic. However, all pre-existing models have limitations which include ethical constraints. Therefore, efforts to reduce and/or replace
Autor:
Sandra M. Newton, Nitya Krishnan, Jasmeet Singh Khara, Yi Yan Yang, Paul R. Langford, Ying Wang, Iria Uhía, Brian D. Robertson, Melissa Hamilton, Pui Lai Rachel Ee, Miles Priestman
Publikováno v:
Journal of Antimicrobial Chemotherapy. 71:2181-2191
Objectives The emergence of MDR-TB, coupled with shrinking antibiotic pipelines, has increased demands for new antimicrobials with novel mechanisms of action. Antimicrobial peptides have increasingly been explored as promising alternatives to antibio