Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Jasmeet S Reyat"'
Autor:
Winnie Chua, Victor R. Cardoso, Eduard Guasch, Moritz F. Sinner, Christoph Al-Taie, Paul Brady, Barbara Casadei, Harry J. G. M. Crijns, Elton A. M. P. Dudink, Stéphane N. Hatem, Stefan Kääb, Peter Kastner, Lluis Mont, Frantisek Nehaj, Yanish Purmah, Jasmeet S. Reyat, Ulrich Schotten, Laura C. Sommerfeld, Stef Zeemering, André Ziegler, Georgios V. Gkoutos, Paulus Kirchhof, Larissa Fabritz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Early detection of atrial fibrillation (AF) enables initiation of anticoagulation and early rhythm control therapy to reduce stroke, cardiovascular death, and heart failure. In a cross-sectional, observational study, we aimed to identify a c
Externí odkaz:
https://doaj.org/article/d1c609a3c0d54b6f920d0755d796b56f
Autor:
Caitlin Hall, Jonathan P. Law, Jasmeet S. Reyat, Max J. Cumberland, Shaun Hang, Nguyen T. N. Vo, Kavita Raniga, Chris J. Weston, Christopher O’Shea, Jonathan N. Townend, Katja Gehmlich, Charles J. Ferro, Chris Denning, Davor Pavlovic
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Activation of cardiac fibroblasts and differentiation to myofibroblasts underlies development of pathological cardiac fibrosis, leading to arrhythmias and heart failure. Myofibroblasts are characterised by increased α-smooth muscle actin (
Externí odkaz:
https://doaj.org/article/0120de0a24174c8798d8cc3427fd584c
Autor:
Jasmeet S. Reyat, Alessandro di Maio, Beata Grygielska, Jeremy Pike, Samuel Kemble, Antonio Rodriguez-Romero, Christina Simoglou Karali, Adam P. Croft, Bethan Psaila, Filipa Simões, Julie Rayes, Abdullah O. Khan
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionRecent advances in human cardiac 3D approaches have yielded progressively more complex and physiologically relevant culture systems. However, their application in the study of complex pathological processes, such as inflammation and fibro
Externí odkaz:
https://doaj.org/article/3399289f4d04440a98842fe8c911f425
Autor:
Sophie Broadway-Stringer, He Jiang, Kirsty Wadmore, Charlotte Hooper, Gillian Douglas, Violetta Steeples, Amar J. Azad, Evie Singer, Jasmeet S. Reyat, Frantisek Galatik, Elisabeth Ehler, Pauline Bennett, Jacinta I. Kalisch-Smith, Duncan B. Sparrow, Benjamin Davies, Kristina Djinovic-Carugo, Mathias Gautel, Hugh Watkins, Katja Gehmlich
Publikováno v:
Cells, Vol 12, Iss 5, p 721 (2023)
Pathogenic variants in ACTN2, coding for alpha-actinin 2, are known to be rare causes of Hypertrophic Cardiomyopathy. However, little is known about the underlying disease mechanisms. Adult heterozygous mice carrying the Actn2 p.Met228Thr variant wer
Externí odkaz:
https://doaj.org/article/0ba42ffd89aa445d9501041c0b0f406d
Autor:
Abdullah O. Khan, Alexandre Slater, Annabel Maclachlan, Phillip L.R. Nicolson, Jeremy A. Pike, Jasmeet S. Reyat, Jack Yule, Rachel Stapley, Julie Rayes, Steven G. Thomas, Neil V. Morgan
Publikováno v:
Haematologica, Vol 107, Iss 1 (2020)
In specialized cells, the expression of specific tubulin isoforms and their subsequent post-translational modifications drive and coordinate unique morphologies and behaviors. The mechanisms by which β1-tubulin, the platelet and megakaryocyte (MK) l
Externí odkaz:
https://doaj.org/article/499818eef52141fda25ba5aa4841cfc0
Autor:
Martina Colicchia, Waltraud C. Schrottmaier, Gina Perrella, Jasmeet S. Reyat, Jenefa Begum, Alexandre Slater, Joshua Price, Joanne C. Clark, Zhaogong Zhi, Megan J. Simpson, Joshua H. Bourne, Natalie S. Poulter, Abdullah O. Khan, Phillip L. R. Nicolson, Matthew Pugh, Paul Harrison, Asif J. Iqbal, George E. Rainger, Steve P. Watson, Mark R. Thomas, Nicola J. Mutch, Alice Assinger, Julie Rayes
Publikováno v:
Blood, 140(24), 2626-2643. The American Society of Hematology
S100A8/A9, also known as “calprotectin” or “MRP8/14,” is an alarmin primarily secreted by activated myeloid cells with antimicrobial, proinflammatory, and prothrombotic properties. Increased plasma levels of S100A8/A9 in thrombo-inflammatory
Autor:
Jasmeet S. Reyat, Winnie Chua, Victor R. Cardoso, Anika Witten, Peter M. Kastner, S. Nashitha Kabir, Moritz F. Sinner, Robin Wesselink, Andrew P. Holmes, Davor Pavlovic, Monika Stoll, Stefan Kääb, Georgios V. Gkoutos, Joris R. de Groot, Paulus Kirchhof, Larissa Fabritz
Publikováno v:
JCI Insight, Vol 5, Iss 16 (2020)
BACKGROUND Genomic and experimental studies suggest a role for PITX2 in atrial fibrillation (AF). To assess if this association is relevant for recurrent AF in patients, we tested whether left atrial PITX2 affects recurrent AF after AF ablation.METHO
Externí odkaz:
https://doaj.org/article/f0ceb91cf1c64eb28dce8b403521e23a
Autor:
Bethan Psaila, Kellie R. Machlus, Julie Rayes, Sarah Gooding, Anindita Roy, Gowsihan Poologasundarampillai, David Bassett, Adam P. Croft, Adele K. Fielding, Emily A. Cutler, Samuel Kemble, Andrew P. Stone, Christina Simoglou Karali, Natalina E. Elliott, Rebecca E. Ling, Christopher B. Mahony, Gina Perrella, Beata Grygielska, Lauren C. Murphy, Nikolaos Sousos, Wei Xiong Wen, Guanlin Wang, Michela Colombo, Aude-Anais Olijnik, Jasmeet S. Reyat, Antonio Rodriguez-Romera, Abdullah O. Khan
Supplementary Materials and Methods, Supplementary Figures S1-S12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a573fe1453225026bed96d9d784dfaf8
https://doi.org/10.1158/2159-8290.22541647.v1
https://doi.org/10.1158/2159-8290.22541647.v1
Autor:
Bethan Psaila, Kellie R. Machlus, Julie Rayes, Sarah Gooding, Anindita Roy, Gowsihan Poologasundarampillai, David Bassett, Adam P. Croft, Adele K. Fielding, Emily A. Cutler, Samuel Kemble, Andrew P. Stone, Christina Simoglou Karali, Natalina E. Elliott, Rebecca E. Ling, Christopher B. Mahony, Gina Perrella, Beata Grygielska, Lauren C. Murphy, Nikolaos Sousos, Wei Xiong Wen, Guanlin Wang, Michela Colombo, Aude-Anais Olijnik, Jasmeet S. Reyat, Antonio Rodriguez-Romera, Abdullah O. Khan
Supplementary Table 3 HD and MPN samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456e3dfa7f46e74c72aebbc2fce7d73a
https://doi.org/10.1158/2159-8290.22541662.v1
https://doi.org/10.1158/2159-8290.22541662.v1
Autor:
Bethan Psaila, Kellie R. Machlus, Julie Rayes, Sarah Gooding, Anindita Roy, Gowsihan Poologasundarampillai, David Bassett, Adam P. Croft, Adele K. Fielding, Emily A. Cutler, Samuel Kemble, Andrew P. Stone, Christina Simoglou Karali, Natalina E. Elliott, Rebecca E. Ling, Christopher B. Mahony, Gina Perrella, Beata Grygielska, Lauren C. Murphy, Nikolaos Sousos, Wei Xiong Wen, Guanlin Wang, Michela Colombo, Aude-Anais Olijnik, Jasmeet S. Reyat, Antonio Rodriguez-Romera, Abdullah O. Khan
Supplementary Table 1 VEGFAC Top Differentially Expressed Genes by Cluster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c040ad7afc2e3aecac97e99688b811
https://doi.org/10.1158/2159-8290.22541668
https://doi.org/10.1158/2159-8290.22541668