Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jasleen K. Grewal"'
Autor:
Jake Lever, Martin R. Jones, Arpad M. Danos, Kilannin Krysiak, Melika Bonakdar, Jasleen K. Grewal, Luka Culibrk, Obi L. Griffith, Malachi Griffith, Steven J. M. Jones
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-16 (2019)
Abstract Background Precision oncology involves analysis of individual cancer samples to understand the genes and pathways involved in the development and progression of a cancer. To improve patient care, knowledge of diagnostic, prognostic, predispo
Externí odkaz:
https://doaj.org/article/6895b455f4b64a50aa070e6e9642ac60
Autor:
Basile Tessier‐Cloutier, Jasleen K Grewal, Martin R Jones, Erin Pleasance, Yaoqing Shen, Ellen Cai, Chris Dunham, Lynn Hoang, Basil Horst, David G Huntsman, Diana Ionescu, Anthony N Karnezis, Anna F Lee, Cheng Han Lee, Tae Hoon Lee, David DW Twa, Andrew J Mungall, Karen Mungall, Julia R Naso, Tony Ng, David F Schaeffer, Brandon S Sheffield, Brian Skinnider, Tyler Smith, Laura Williamson, Ellia Zhong, Dean A Regier, Janessa Laskin, Marco A Marra, C Blake Gilks, Steven JM Jones, Stephen Yip
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 4, Pp 395-407 (2022)
Abstract In this study, we evaluate the impact of whole genome and transcriptome analysis (WGTA) on predictive molecular profiling and histologic diagnosis in a cohort of advanced malignancies. WGTA was used to generate reports including molecular al
Externí odkaz:
https://doaj.org/article/a901dba17e554a43930f20607375541d
Autor:
Cameron J. Grisdale, Scott D. Brown, Kevin Y. Fan, Wei Zhang, Caralyn Reisle, Zoltan Bozoky, Robert A. Holt, Tariq Vira, Richard Corbett, Melika Bonakdar, My Linh Thibodeau, Kathleen Wee, Dean Cheng, Luka Culibrk, Marcus Carreira, David F. Schaeffer, Deirdre Weymann, Anna V. Tinker, Eric Y. Zhao, Michael K.C. Lee, Karen A. Gelmon, Karen Mungall, Richard A. Moore, Dean A. Regier, Daniel J. Renouf, Zusheng Zong, Reva Shenwai, Stephen Chia, Jahanshah Ashkani, Ana Fisic, Stephen Yip, Darryl D’Souza, Yussanne Ma, Daniel MacMillan, Erin Pleasance, Steve Bilobram, Alexandra Fok, Amir Muhammadzadeh, Jean-Michel Lavoie, Martin R. Jones, Hillary Pearson, Simon K. Chan, Balvir Deol, Steven J.M. Jones, Andrew J. Mungall, Mya Warren, Gregory A. Taylor, Elisa Majounie, Harwood H. Kwan, Eric Chuah, Howard John Lim, Sara Sadeghi, Dustin Bleile, Emma Titmuss, Reanne Bowlby, Anna Davies, Laura Williamson, Jessica Nelson, Caleb Choo, Jasleen K. Grewal, Katherine Dixon, Yongjun Zhao, Shehara Mendis, Yaoqing Shen, Janessa Laskin, Joanna M. Karasinska, Veronika Csizmok, Tina Wong, Sophie Sun, Kasmintan A. Schrader, Marco A. Marra
Publikováno v:
Nature Cancer. 1:452-468
Advanced and metastatic tumors with complex treatment histories drive cancer mortality. Here we describe the POG570 cohort, a comprehensive whole-genome, transcriptome and clinical dataset, amenable for exploration of the impacts of therapies on geno
Autor:
Janessa Laskin, Emma Titmuss, Krista Noonan, Melika Bonakdar, Christine Simmons, Howard John Lim, Eric Y. Zhao, Karen A. Gelmon, Kong Khoo, Martin L. Jones, M. Knowling, Tony Ng, Yaoqing Shen, Greg Taylor, Jennifer Rauw, Eric Chuah, Jasleen K. Grewal, Jason Hart, R. Petter Tonseth, Stephen Yip, Amirrtha Srikanthan, Simon K. Chan, Karen Mungall, S. Rod Rassekh, Sara Kristina Taylor, Yongjun Zhao, Nissreen Mohammad, Xiaolan Feng, Rebecca J. Deyell, Daniel J. Renouf, Andrew J. Mungall, Ursula Lee, Marco A. Marra, Richard D. Moore, Caralyn Reisle, Erin Pleasance, Steven J.M. Jones
Publikováno v:
JCO Precision Oncology. :1-25
PURPOSE This study investigated therapeutic potential of integrated genome and transcriptome profiling of metastatic sarcoma, a rare but extremely heterogeneous group of aggressive mesenchymal malignancies with few systemic therapeutic options. METHO
Autor:
Arpad Danos, Obi L. Griffith, Jake Lever, Jasleen K. Grewal, Martin R. Jones, Luka Culibrk, Steven J.M. Jones, Melika Bonakdar, Malachi Griffith, Kilannin Krysiak
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-16 (2019)
Genome Medicine
Genome Medicine
Background Precision oncology involves analysis of individual cancer samples to understand the genes and pathways involved in the development and progression of a cancer. To improve patient care, knowledge of diagnostic, prognostic, predisposing, and
Autor:
Marco A. Marra, Janessa Laskin, Steven J.M. Jones, Karen Mungall, Laura Williamson, Jasleen K. Grewal, Luka Culibrk, Erin Pleasance
Cancers routinely exhibit chromosomal instability, resulting in the accumulation of changes in the abundance of genomic material, known as copy number variants (CNVs). Unfortunately, the detection of these variants in cancer genomes is difficult. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ef7993ee63ede918f2a76b839a258c7
https://doi.org/10.1101/2021.08.06.455329
https://doi.org/10.1101/2021.08.06.455329
Autor:
Arvind Singh Mer, Spencer Krieger, Nazeefa Fatima, Jasleen K. Grewal, Farzana Rahman, Wim L. Cuypers, Bart Cuypers, Chase Donnelly, Handan Melike Dönertaş
Publikováno v:
F1000Research
In this meeting overview, we summarise the scientific program and organisation of the 16th International Society for Computational Biology Student Council Symposium in 2020 (ISCB SCS2020). This symposium was the first virtual edition in an uninterrup
Autor:
Jasleen K. Grewal, Colin Schlosser, Adrian B. Levine, Robin Coope, Stephen Yip, Steve J.M. Jones
Publikováno v:
Trends in Cancer. 5:157-169
Deep learning refers to a set of computer models that have recently been used to make unprecedented progress in the way computers extract information from images. These algorithms have been applied to tasks in numerous medical specialties, most exten
Publikováno v:
Nature Methods. 16:505-507
Tumors from individuals with cancer are frequently genetically profiled for information about the driving forces behind the disease. We present the CancerMine resource, a text-mined and routinely updated database of drivers, oncogenes and tumor suppr
Publikováno v:
Nature Methods. 17:121-122
“With one eye you are looking at the outside world, while with the other you are looking within yourself.” —Amedeo Modigliani