Výsledky vyhledávání - "Jasdeep Nagra"

The Epstein-Barr Virus BamHI C Promoter Is Not Essential for B Cell Immortalization In Vitro , but It Greatly Enhances B Cell Growth Transformation

Autor: Rosemary J. Tierney, Jasdeep Nagra, Andrew I. Bell, Alan B. Rickinson, Martin Rowe

Publikováno v: Journal of Virology. 89:2483-2493

Epstein-Barr virus (EBV) infection of B cells leads to the sequential activation of two viral promoters, Wp and Cp, resulting in the expression of six EBV nuclear antigens (EBNAs) and the viral Bcl2 homologue BHRF1. The viral transactivator EBNA2 is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2081a7e48b7c66a33da216924091e872
https://doi.org/10.1128/jvi.03300-14

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Epstein-Barr Virus BamHI W Repeat Number Limits EBNA2/EBNA-LP Coexpression in Newly Infected B Cells and the Efficiency of B-Cell Transformation: a Rationale for the Multiple W Repeats in Wild-Type Virus Strains

Autor: Kuan-Yu Kao, Rosemary J. Tierney, Jasdeep Nagra, Alan B. Rickinson

Publikováno v: Journal of Virology. 85:12362-12375

The genome of Epstein-Barr virus (EBV), a gammaherpesvirus with potent B-cell growth-transforming ability, contains multiple copies of a 3-kb BamHI W repeat sequence; each repeat carries (i) a promoter (Wp) that initiates transformation by driving EB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe36769279e04e8233418d26f23f56d
https://doi.org/10.1128/jvi.06059-11

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Epstein-Barr Virus Exploits BSAP/Pax5 To Achieve the B-Cell Specificity of Its Growth-Transforming Program

Autor: Alan B. Rickinson, Wolfgang Hammerschmidt, Rosemary J. Tierney, Isabel A. Hutchings, Andrew I. Bell, Claire Shannon-Lowe, Markus Altmann, Jasdeep Nagra

Publikováno v: J. Virol. 81, 10092-10100 (2007)

Epstein-Barr virus (EBV) can infect various cell types but limits its classical growth-transforming function to B lymphocytes, the cells in which it persists in vivo. Transformation initiates with the activation of Wp, a promoter present as tandemly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c360a9300a277c7fc10b17f599845745
https://doi.org/10.1128/jvi.00358-07

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Methylation of Transcription Factor Binding Sites in the Epstein-Barr Virus Latent Cycle Promoter Wp Coincides with Promoter Down-Regulation during Virus-Induced B-Cell Transformation

Autor: Helen Kirby, Rosemary J. Tierney, Alan B. Rickinson, J. Desmond, Jasdeep Nagra, Andrew I. Bell

Publikováno v: Journal of Virology. 74:10468-10479

Two Epstein-Barr virus latent cycle promoters for nuclear antigen expression, Wp and Cp, are activated sequentially during virus-induced transformation of B cells to B lymphoblastoid cell lines (LCLs) in vitro. Previously published restriction enzyme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d70cb3e749f655f506e9e5ecbab1769d
https://doi.org/10.1128/jvi.74.22.10468-10479.2000

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The Epstein-Barr Virus Promoter Initiating B-Cell Transformation Is Activated by RFX Proteins and the B-Cell-Specific Activator Protein BSAP/Pax5

Autor: Alan B. Rickinson, Helen Kirby, Rosemary J. Tierney, Jasdeep Nagra, Andrew I. Bell

Epstein-Barr virus (EBV)-induced B-cell growth transformation, a central feature of the virus' strategy for colonizing the human B-cell system, requires full virus latent gene expression and is initiated by transcription from the viral promoter Wp. I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6b2aaab858515a1ce7ab780dae3e0f
https://europepmc.org/articles/PMC110920/

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