Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jascha Blobel"'
Publikováno v:
Journal of Cheminformatics, Vol 13, Iss 1, Pp 1-16 (2021)
Abstract In recent years, individual and collective human intelligence, defined as the knowledge, skills, reasoning and intuition of individuals and groups, have been used in combination with computer algorithms to solve complex scientific problems.
Externí odkaz:
https://doaj.org/article/b33ae148e7ea44569fb68af526547e80
Publikováno v:
Journal of Cheminformatics
Journal of Cheminformatics, Vol 13, Iss 1, Pp 1-16 (2021)
Journal of Cheminformatics, Vol 13, Iss 1, Pp 1-16 (2021)
In recent years, individual and collective human intelligence, defined as the knowledge, skills, reasoning and intuition of individuals and groups, have been used in combination with computer algorithms to solve complex scientific problems. Such appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d217a8fc64044e4cace537139f8521
http://europepmc.org/articles/PMC8507178
http://europepmc.org/articles/PMC8507178
In recent years, individual and collective human intelligence, defined as the knowledge, skills, reasoning and intuition of individuals and groups, have been used in combination with computer algorithms to solve complex scientific problems. Such appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c399991e3814d48d44de7eff9157334c
https://doi.org/10.26434/chemrxiv.13354328
https://doi.org/10.26434/chemrxiv.13354328
In recent years, individual and collective human intelligence, defined as the knowledge, skills, reasoning and intuition of individuals and groups, have been used in combination with computer algorithms to solve complex scientific problems. Such appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a781f7c54719afa4207458a987291b33
https://doi.org/10.26434/chemrxiv.13354328.v1
https://doi.org/10.26434/chemrxiv.13354328.v1
Autor:
Miquel Pons, Jascha Blobel, Mikael Akke, Carl Diehl, Alejandra Sornosa, Ulrika Brath, Lidia Ballester, Pau Bernadó
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Addition of a 50 mM mixture of L: -arginine and L: -glutamic acid (RE) is extensively used to improve protein solubility and stability, although the origin of the effect is not well understood. We present Small Angle X-ray Scattering (SAXS) and Nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cfc4dc5e060c7e01d5e63c1f973770
https://doi.org/10.1007/s00249-011-0686-3
https://doi.org/10.1007/s00249-011-0686-3
Publikováno v:
FEBS Journal. 276:4346-4357
The well-characterized self-association of a mammalian low-molecular-weight protein tyrosine phosphatase (lmwPTP) produces inactive oligomers that are in equilibrium with active monomers. A role of the inactive oligomers as supramolecular proenzymes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee77063d404a6340bf8ea934500da7f8
https://doi.org/10.1111/j.1742-4658.2009.07139.x
https://doi.org/10.1111/j.1742-4658.2009.07139.x
Publikováno v:
Comptes Rendus Chimie. 11:499-505
The interaction of low-molecular-weight ligands with proteins in the search for new selective drugs is driving great efforts in the pharmaceutical industry and academic research. The same principles can be applied to solve an equally challenging task
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d6c562c7223b292c135057c66d111d9
https://doi.org/10.1016/j.crci.2007.08.015
https://doi.org/10.1016/j.crci.2007.08.015
Autor:
Dmitri I. Svergun, Yolanda Pérez, Pau Bernadó, Miquel Pons, Jascha Blobel, Juan Fernández-Recio
Publikováno v:
Protein science : a publication of the Protein Society. 18(4)
Signal transducer and activator of transcription (STAT) proteins play a crucial role in the activation of gene transcription in response to extracellular stimuli. The regulation and activity of these proteins require a complex rearrangement of the do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11aefc962486ee8f67af5962146e5771
https://pubmed.ncbi.nlm.nih.gov/19309697
https://pubmed.ncbi.nlm.nih.gov/19309697
Publikováno v:
Journal of the American Chemical Society 131, 4378-4386 (2009). doi:10.1021/ja808490b
Journal of the American Chemical Society 131, 4378-4386 (2009). doi:10.1021/ja808490b
The determination of the three-dimensional structure of a weak protein-protein complex in solution using small-angle X-ray scattering requires the deconvolutio
The determination of the three-dimensional structure of a weak protein-protein complex in solution using small-angle X-ray scattering requires the deconvolutio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a207b6b5e4d9d47eb7b89d4cebabaf5c
https://bib-pubdb1.desy.de/record/93058
https://bib-pubdb1.desy.de/record/93058
Autor:
Eike Brunner, David Vidal, Jascha Blobel, Sabine Schmidl, Lydia Nisius, Miquel Pons, Oscar Millet, Pau Bernadó
Publikováno v:
Journal of the American Chemical Society. 129(18)
15N NMR relaxation and 129Xe NMR chemical shift measurements offer complementary information to study weak protein-protein interactions. They have been applied to study the oligomerization equilibrium of a low-molecular-weight protein tyrosine phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612834466adfbd00f2eec3e0c105561e
https://pubmed.ncbi.nlm.nih.gov/17439119
https://pubmed.ncbi.nlm.nih.gov/17439119