Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jascha B Pohl"'
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75549 (2013)
Drug tolerance and withdrawal are insidious responses to drugs of abuse; the first increases drug consumption while the second punishes abstention. Drosophila generate functional tolerance to benzyl alcohol sedation by increasing neural expression of
Externí odkaz:
https://doaj.org/article/393ab1ee3d8d455d999e86953a5283e9
Autor:
Brooks G Robinson, Sukant Khurana, Jascha B Pohl, Wen-ke Li, Alfredo Ghezzi, Amanda M Cady, Kristina Najjar, Michael M Hatch, Ruchita R Shah, Amar Bhat, Omar Hariri, Kareem B Haroun, Melvin C Young, Kathryn Fife, Jeff Hooten, Tuan Tran, Daniel Goan, Foram Desai, Farhan Husain, Ryan M Godinez, Jeffrey C Sun, Jonathan Corpuz, Jacxelyn Moran, Allen C Zhong, William Y Chen, Nigel S Atkinson
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37394 (2012)
Drosophila melanogaster has proven to be a useful model system for the genetic analysis of ethanol-associated behaviors. However, past studies have focused on the response of the adult fly to large, and often sedating, doses of ethanol. The pharmacol
Externí odkaz:
https://doaj.org/article/f53db8d35c1548d4878dd247cceb889a
Autor:
Arun Y. Bohm, Harish R. Krishnan, Nigel S. Atkinson, Xiaolei Li, Jascha B. Pohl, Alfredo Ghezzi
Publikováno v:
Journal of Neurogenetics. 29:124-134
The slo gene encodes the BK-type Ca(2+)-activated K(+) channels. In Drosophila, expression of slo is induced by organic solvent sedation (benzyl alcohol and ethanol), and this increase in neural slo expression contributes to the production of functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e434cb43ba91fa96b339dbcbe4ff7197
https://doi.org/10.3109/01677063.2015.1050097
https://doi.org/10.3109/01677063.2015.1050097
Autor:
Lawrence K. Cormack, Nigel S. Atkinson, Roseanna B. Robles, Alfredo Ghezzi, Jascha B. Pohl, Linda K. Lew
Publikováno v:
Alcoholism: Clinical and Experimental Research. 37:1862-1871
There is a strong relationship between circadian rhythms and ethanol (EtOH) responses. EtOH consumption has been shown to disrupt physiological and behavioral circadian rhythms in mammals (Alcohol Clin Exp Res 2005b, 29, 1550). The Drosophila central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5a68d729712089b77f6e4d4d5ccb40
https://doi.org/10.1111/acer.12173
https://doi.org/10.1111/acer.12173
Autor:
Nigel S. Atkinson, Boingoc L. Dinh, Brett A. Baldwin, Jascha B. Pohl, Nyssa Sherazee, Francisco J. Prado, Dustin Smerek, Pinkey Rahman
Publikováno v:
Alcoholism: Clinical and Experimental Research. 36:1903-1912
Background Perhaps the most difficult thing to ascertain concerning the behavior of another animal is its motivation. The motivation underlying the preference of Drosophila melanogaster for ethanol (EtOH)-rich food has long been ascribed to its value
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce29eef47404dc0ed57461ffac91f081
https://doi.org/10.1111/j.1530-0277.2012.01817.x
https://doi.org/10.1111/j.1530-0277.2012.01817.x
Publikováno v:
Alcoholism: Clinical and Experimental Research. 36:24-34
Background: A prevailing hypothesis is that the set of genes that underlie the endophenotypes of alcoholism overlap with those responsible for the addicted state. Functional ethanol tolerance, an endophenotype of alcoholism, is defined as a reduced r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3cb0845530b2a70e1d478845e59c0f0
https://doi.org/10.1111/j.1530-0277.2011.01587.x
https://doi.org/10.1111/j.1530-0277.2011.01587.x
Publikováno v:
Proceedings of the National Academy of Sciences. 107:16360-16365
Disturbance of neural activity by sedative drugs has been proposed to trigger a homeostatic response that resists unfavorable changes in net cellular excitability, leading to tolerance and dependence. The Drosophila slo gene encodes a BK-type Ca 2+ -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981538d89867ccb564233e0580cd2e4c
https://doi.org/10.1073/pnas.1005439107
https://doi.org/10.1073/pnas.1005439107
Autor:
Andrew P. Vreede, Nathan C. Peabody, Benjamin H. White, Jascha B. Pohl, Fengqiu Diao, Paul K. Zelensky, David J. Sandstrom, Howard Wang
Publikováno v:
The Journal of Neuroscience. 29:3343-3353
After emergence, adult flies and other insects select a suitable perch and expand their wings. Wing expansion is governed by the hormone bursicon and can be delayed under adverse environmental conditions. How environmental factors delay bursicon rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6610faf8a3d7bb624008d78c4c52e00
https://doi.org/10.1523/jneurosci.4241-08.2009
https://doi.org/10.1523/jneurosci.4241-08.2009
Publikováno v:
Alcoholism, clinical and experimental research. 36(1)
A prevailing hypothesis is that the set of genes that underlie the endophenotypes of alcoholism overlap with those responsible for the addicted state. Functional ethanol tolerance, an endophenotype of alcoholism, is defined as a reduced response to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f17ba7d633c45d95a9bda6ff8ad561d
https://pubmed.ncbi.nlm.nih.gov/21797886
https://pubmed.ncbi.nlm.nih.gov/21797886
Autor:
William C. Lemon, Benjamin H. White, Haojiang Luan, Jascha B. Pohl, Nathan C. Peabody, Ding Wang, Todd C. Holmes, Paul K. Zelensky, Michael N. Nitabach
A subset ofDrosophilaneurons that expresses crustacean cardioactive peptide (CCAP) has been shown previously to make the hormone bursicon, which is required for cuticle tanning and wing expansion after eclosion. Here we present evidence that CCAP-exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e192c7a4dae171dd56f3d49805a2037
https://europepmc.org/articles/PMC1857274/
https://europepmc.org/articles/PMC1857274/
