Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Jasbir Seehra"'
Autor:
Blake Moses, Ashlyn Wheeler, Mike Dills, Samuel Cadena, Lorena Lerner, Jasbir Seehra, Jenn Lachey
Publikováno v:
HemaSphere, Vol 7, p e10730ab (2023)
Externí odkaz:
https://doaj.org/article/54978d612bff43cb8b0bd3e7e0832357
Autor:
Chia-Yu Wang, Emiliano Melgar-Bermudez, Diana Welch, Claire Tseng, Ffolliott Fisher, Samuel Cadena, Lorena Lerner, Jasbir Seehra, Jenn Lachey
Publikováno v:
HemaSphere, Vol 7, p e253136f (2023)
Externí odkaz:
https://doaj.org/article/ec8eba71ac5e4e17b24156f1bdd1291c
Publikováno v:
Fair Disclosure Wire (Quarterly Earnings Reports). 09/04/2024.
Autor:
Ravindra Kumar, Jasbir Seehra, Kathryn W. Underwood, R. Scott Pearsall, Jeffrey A. Ucran, Nicolas Solban, Travis E. Monnell, Roselyne Castonguay, Asya V. Grinberg, Aaron W. Mulivor, Eileen G. Pobre, Dianne Mitchell
Activin receptor–like kinase-1 (ALK1) is a type I, endothelial cell–specific member of the transforming growth factor-β superfamily of receptors known to play an essential role in modulating angiogenesis and vessel maintenance. In the present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d62b66268345b52b0f0b8aa7db8311c
https://doi.org/10.1158/1535-7163.c.6532256
https://doi.org/10.1158/1535-7163.c.6532256
Autor:
Ravindra Kumar, Jasbir Seehra, Kathryn W. Underwood, R. Scott Pearsall, Jeffrey A. Ucran, Nicolas Solban, Travis E. Monnell, Roselyne Castonguay, Asya V. Grinberg, Aaron W. Mulivor, Eileen G. Pobre, Dianne Mitchell
Supplementary Table 1 from ALK1-Fc Inhibits Multiple Mediators of Angiogenesis and Suppresses Tumor Growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5eebbcf9ce0bdb38c2a3af3223ee68
https://doi.org/10.1158/1535-7163.22486142
https://doi.org/10.1158/1535-7163.22486142
Autor:
Blake S Moses, Chris Materna, Remya Nathan, Tandicka Nurse, Keith Babbs, Claire Tseng, Ffolliott Fisher, Jasbir Seehra, Jenn Lachey
Publikováno v:
Blood. 140:9763-9764
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdb1d94f26d90f4e983e3cb13b7c1619
https://doi.org/10.1182/blood-2022-169360
https://doi.org/10.1182/blood-2022-169360
Autor:
Chia-Yu Wang, Emiliano Melgar-Bermudez, Diana Welch, Claire C Tseng, Ffolliott Fisher, Samuel M Cadena, Lorena Lerner, Jasbir Seehra, Jenn Lachey
Publikováno v:
Blood. 140:5337-5338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d83da3c584be625b963c7fbf7239a6ad
https://doi.org/10.1182/blood-2022-166838
https://doi.org/10.1182/blood-2022-166838
Publikováno v:
Circulation. 144
Pulmonary arterial hypertension (PAH) is a debilitating disorder, characterized by right ventricle (RV) pressure overload, cardiac hypertrophy, and progressive RV dysfunction. PAH is associated with unbalanced TGFß signaling, favoring signaling of S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7139b92311f7aa47c6a927a267e46ee2
https://doi.org/10.1161/circ.144.suppl_1.11209
https://doi.org/10.1161/circ.144.suppl_1.11209
Autor:
Jasbir Seehra, Jenn Lachey, Marina Feigenson, Joshua Lamora, Ffolliott Fisher, Claire C Tseng, Remya Nathan
Publikováno v:
Blood. 138:2068-2068
KER-050 is a modified ActRIIA ligand trap that is designed to inhibit the activity of the TGF-β ligands, including activin A, activin B, GDF8 and GDF11, that act through the SMAD2/3 signaling cascade. Notably, in a Phase 1 clinical study we observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ad49a1a651f25bb8ca197545ba45a52
https://doi.org/10.1182/blood-2021-152814
https://doi.org/10.1182/blood-2021-152814
Autor:
Ffolliott Fisher, Remya Nathan, Claire C Tseng, Joshua Lamora, Jasbir Seehra, Marina Feigenson, Jenn Lachey
Publikováno v:
Blood. 138:934-934
Myelofibrosis (MF) is characterized by the dysfunctional Janus kinase/signal transducers and activators of transcription signaling (JAK/STAT) pathways leading to progressive proliferation of granulocytic and megakaryocytic cells in the bone marrow at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4256a4c0f43692f2617d3219b1fbb05a
https://doi.org/10.1182/blood-2021-152729
https://doi.org/10.1182/blood-2021-152729