Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jas Seehra"'
Autor:
Carolyn H. Condon, Matthew L. Sherman, Ravi Kumar, Dawn Wilson, Jas Seehra, Debbie A. Willins, Yijun Yang, Niels Borgstein, Amelia E. Pearsall, Kenneth M. Attie
Publikováno v:
Muscle & Nerve. 47:416-423
Introduction ACE-031 is a soluble form of activin receptor type IIB (ActRIIB). ACE-031 promotes muscle growth by binding to myostatin and other negative regulators of muscle mass. Methods This double-blind, placebo-controlled study evaluated the safe
Autor:
Gilda Tachedjian, Martha de los Santos, Jas Seehra, Stephen P. Goff, Hans-Erik G. Aronson, John M. Mccoy
Publikováno v:
Journal of Molecular Biology. 326:381-396
The tryptophan repeat motif of the human immunodeficiency virus type-1 (HIV-1) reverse transcriptase (RT) is comprised of a cluster of six tryptophan residues at codons 398, 401, 402, 406, 410 and 414 that are highly conserved amongst primate lentivi
Autor:
Jas Seehra, Les Coulton, Karin Vanderkerken, Deborah J. Heath, Holly Evans, Nicole Abdul, Peter I. Croucher, Andrew D Chantry
Publikováno v:
Cancer Treatment Reviews. 34:13-14
Autor:
Kathryn W. Underwood, Aaron W. Mulivor, Samuel M. Cadena, Ravindra Kumar, Jas Seehra, R. Scott Pearsall, Rajasekhar N.V.S. Suragani
Publikováno v:
Blood. 116:978-978
Abstract 978 Myelodysplastic syndrome (MDS) is a premalignant disease characterized by ineffective hematopoiesis. MDS patients can live for extended periods of time but can develop severe anemia or may progress to acute leukemia. Current therapies re
Autor:
Ravi Kumar, Matthew L. Sherman, Denise Barbosa, Aaron W. Mulivor, R. Scott Pearsall, Jas Seehra
Publikováno v:
Blood. 114:161-161
Abstract 161 Anemia is a common and often severe side-effect of chemotherapy treatment that can alter treatment regimens and can frequently require patients to receive blood transfusions. The majority of therapies approved for anemia target the eryth
Autor:
Jesse Schoonmaker, Eyal C. Attar, David T. Scadden, Jas Seehra, Alexander R. Guimaraes, Samantha Pozzi, Kenneth C. Anderson, Loredana Santo, Teru Hideshima, Chirayu G. Patel, Noopur Raje, Sonia Vallet, Diana Cirstea, Aliyah Rahemtullah, Nileshwari Vaghela, Nikhil C. Munshi, Wanling Xie, Mariateresa Fulciniti, Edie Weller, Siddhartha Mukherjee
Publikováno v:
ResearcherID
A distinct feature of multiple myeloma (MM) is the tight interaction between malignant plasma cells and their bone microenvironment, creating a niche suitable for MM growth. In particular, MM cells inhibit osteoblast (OB) differentiation and stimulat