Losartan to slow the progression of mild-to-moderate Alzheimer’s disease through angiotensin targeting: the RADAR RCT

Autor: Kehoe PG; Dementia Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK, Turner N; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK, Howden B; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK, Jarutyt L; ReMemBr Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK, Clegg SL; Dementia Research Centre (DRC), Institute of Neurology, University College London, London, UK, Malone IB; Dementia Research Centre (DRC), Institute of Neurology, University College London, London, UK, Barnes J; Dementia Research Centre (DRC), Institute of Neurology, University College London, London, UK, Nielsen C; Dementia Research Centre (DRC), Institute of Neurology, University College London, London, UK, Sudre CH; Dementia Research Centre (DRC), Institute of Neurology, University College London, London, UK; School of Biomedical Engineering and Imaging Sciences, King’s College London, London, UK, Wilson A; Clinical Research Imaging Centre, University of Bristol, Bristol, UK, Thai NJ; Clinical Research Imaging Centre, University of Bristol, Bristol, UK, Blair PS; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK, Coulthard EJ; ReMemBr Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK, Lane JA; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK, Passmore P; Institute of Clinical Sciences, Queen’s University Belfast, Royal Victoria Hospital, Belfast, UK, Taylor J; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK, Mutsaerts HJ; Academic Medical Centre, Amsterdam, the Netherlands; Ghent University Hospital, Ghent, Belgium, Thomas DL; Leonard Wolfson Experimental Neurology Centre, UCL Institute of Neurology, London, UK, Fox NC; Dementia Research Centre (DRC), Institute of Neurology, University College London, London, UK; Leonard Wolfson Experimental Neurology Centre, UCL Institute of Neurology, London, UK, Wilkinson I; Clinical Pharmacology Unit, School of Clinical Medicine, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK, Ben-Shlomo Y; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK

Publikováno v: 2021 Nov.