Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jarrod P. Skinner"'
Autor:
Seungyoul Oh, Xin Liu, Sara Tomei, Mengxiao Luo, Jarrod P. Skinner, Stuart P. Berzins, Shalin H. Naik, Daniel H. D. Gray, Mark M. W. Chong
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The αβ and γδ T cell lineages both differentiate in the thymus from common uncommitted progenitors. The earliest stage of T cell development is known as CD4-CD8- double negative 1 (DN1), which has previously been shown to be a heterogenous mixtur
Externí odkaz:
https://doaj.org/article/9b72aa6e5c374c97a013a70b3a3adc47
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0270820 (2022)
Class II myosin complexes are responsible for muscle contraction as well as other non-sarcomeric contractile functions in cells. Myosin heavy chain molecules form the core of these structures, while light chain molecules regulate their stability and
Externí odkaz:
https://doaj.org/article/00b5b03d163e4335aa03d6287b0cdf6e
Publikováno v:
Immunology & Cell Biology. 100:101-111
Regulatory T cells (Tregs) are a specialized immune cell type that play important roles in regulating immune responses. However, those found in adipose tissue, particularly visceral adipose tissue (VAT), have also been shown to exert metabolic regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f475e424cf9a756036d9f2ab7f32054
https://doi.org/10.1111/imcb.12513
https://doi.org/10.1111/imcb.12513
Autor:
Jarrod P Skinner, Maria Ws Chiu, Barbara C Fam, Nicole K. L. Lee, Kesha Rana, Patricia K Russell, Jeffrey D Zajac, Helen E. MacLean
Publikováno v:
Journal of Molecular Endocrinology. 57:125-138
The aim of this study was to investigate the direct muscle cell-mediated actions of androgens by comparing two different mouse lines. The cre-loxP system was used to delete the DNA-binding activity of the androgen receptor (AR) in mature myofibers (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2c171cd5c24b3d6362dda2739e8dff
https://doi.org/10.1530/jme-15-0320
https://doi.org/10.1530/jme-15-0320
Autor:
David M. Findlay, Jeffrey D Zajac, Gerald J. Atkins, Stephen A. Sastra, Paul H. Anderson, Patricia K Russell, Jarrod P Skinner, Rachel A Davey, Michele V Clarke
Publikováno v:
Endocrinology. 156:3203-3214
During lactation, the large transfer of calcium from the mother to the milkis primarily sourced from the maternal skeleton. To determine whether the calcitonin receptor (CTR) plays a physiological role to protect the skeleton from excessive resorptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb255f9b177b0eb524beb7e6ff8d5db
https://doi.org/10.1210/en.2015-1345
https://doi.org/10.1210/en.2015-1345
Autor:
Patricia K Russell, Tammy P S Pang, Rachel A Davey, Michele V Clarke, Jarrod P Skinner, Jeffrey D Zajac
Publikováno v:
Journal of Molecular Endocrinology. 49:1-10
Androgens play a key role in skeletal growth and maintenance in males and can mediate their actions, at least in part, via the androgen receptor (AR) in osteoblasts. To investigate the mechanisms by which androgens exert their effects via the AR in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a479f69495f565a09697182fa2d5a76
https://doi.org/10.1530/jme-12-0014
https://doi.org/10.1530/jme-12-0014
Autor:
Paul H. Anderson, Jeffrey D Zajac, Rachel A Davey, Michele V Clarke, Jarrod P Skinner, Stephen A. Sastra, Cherie Ying Chiang
Conditional gene inactivation using the Cre/loxP system has lead to significant advances in our understanding of the function of genes in a wide range of disciplines. It is becoming increasingly apparent in the literature, that Cre transgenic mice ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11efc17a31b148a6c0d50c1d57ec45dc
https://hdl.handle.net/1959.8/125484
https://hdl.handle.net/1959.8/125484
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 301(1)
The aim of this study is to determine if the Odc1 gene, which encodes ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis, is directly regulated by the androgen receptor (AR) in skeletal muscle myoblasts and if Odc1 regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39ad294404ba805775130ade0e91f5a
https://pubmed.ncbi.nlm.nih.gov/21505150
https://pubmed.ncbi.nlm.nih.gov/21505150
Autor:
Jarrod P Skinner, Rebecca Sawyer, A.J. Moore, Howard A. Morris, Francisca Tjahyono, Jeffrey D Zajac, David M. Findlay, Andrew G. Turner, Rachel A Davey, W.S. Maria Chiu
Despite the therapeutic value of calcitonin in treating bone disease, a biological role of endogenous calcitonin is controversial. Having previously demonstrated that the CTR has a biological role in protecting against calcium stress using a global C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e51d765c70767f834caf729cbfe8f62
https://hdl.handle.net/1959.8/154517
https://hdl.handle.net/1959.8/154517