Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jarrod Dudakov"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/bc4220e5283f4bd288dc3172a7fccf86
Autor:
Emma Mitchell, Shifra L. Klein, Kimon V. Argyropoulos, Ali Sharma, Robin B. Chan, Judit Gal Toth, Luendreo Barboza, Charlotte Bavley, Analia Bortolozzi, Qiuying Chen, Bingfang Liu, Joanne Ingenito, Willie Mark, Jarrod Dudakov, Steven Gross, Gilbert Di Paolo, Francesc Artigas, Marcel van den Brink, Miklos Toth
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Physiological effects of psychological stress and infection in mothers can increase the incidence of anxiety and psychiatric diseases in offsprings and in subsequent generation. Here, Miklos Toth and colleagues show that intergenerational inheritance
Externí odkaz:
https://doaj.org/article/323582df5fd247aa8347bf7b3f2e2348
Autor:
Jennifer L. Uhrlaub, Mladen Jergović, Christine M. Bradshaw, Sandip Sonar, Christopher P. Coplen, Jarrod Dudakov, Kristy O. Murray, Marion C. Lanteri, Michael P. Busch, Marcel R. M. van den Brink, Janko Nikolich‐Žugich
Publikováno v:
Aging cell. 21(4)
Older humans and animals often exhibit reduced immune responses to infection and vaccination, and this often directly correlates to the numbers and frequency of naive T (Tn) cells. We found such a correlation between reduced numbers of blood CD8+ Tn
Autor:
Jennifer Tsai, Jarrod Dudakov, Enrico Velardi, Yusuke Shono, Odette Smith, Tobias Wertheimer, Robert Jenq, Alan Hanash, Marcel Van Den Brink
Publikováno v:
The Journal of Immunology. 194:140.5-140.5
Nuclear factor erythroid-derived 2-like 2 (Nrf2) is an ubiquitously expressed transcription factor, well-known as a master regulator of cellular redox pathway. A recent paper showed that Nrf2 can modulate Th1/Th2 axis in vitro. Here, we evaluated the
Autor:
Jarrod Dudakov, Tobias Wertheimer, Enrico Velardi, Christian Brede, Lauren Young, Michael Ginsberg, Daniel Nolan, Andreas Beilhack, Shahin Rafii, Jason Butler, Marcel Van Den Brink
Publikováno v:
The Journal of Immunology. 194:188.4-188.4
Although the thymus has a remarkable capacity for repair following damage, the mechanisms underlying this endogenous regeneration remain poorly understood. Here we reveal a critical role for endothelial cells (ECs) in aiding thymic recovery following
Autor:
Enrico Velardi, Jennifer Tsai, Lauren Young, Sophie Lieberman, Jyotsna Gupta, Jarrod Dudakov, Marcel Van Den Brink
Publikováno v:
The Journal of Immunology. 194:120.2-120.2
Sex steroid inhibition (SSI) is a well-described strategy to promote lymphopoiesis in the bone marrow and thymus of aged and immunodepleted mice. Although the precise mechanisms underlying this regenerative effect are unclear, there is increasing evi
Autor:
Jarrod Dudakov, Nury Yim, Denzel Cole, Anna Mertelsmann, Margaret O'Connor, Robert Jenq, Enrico Velardi, Lauren Young, Alan Hanash, Marcel van den Brink
Publikováno v:
The Journal of Immunology. 192:202.44-202.44
Innate lymphoid cells (ILC) are a newly described population of immune cells implicated in the maintenance and function of tissues as diverse as liver, gut, lung and lymph nodes. We have recently described a key role for ILC, and their production of
Autor:
Alan Hanash, Jarrod Dudakov, Guoqiang Hua, Chen Liu, Lynette Fouser, Richard Kolesnick, Bruce Blazar, Marcel van den Brink
Publikováno v:
The Journal of Immunology. 188:126.31-126.31
Intestinal graft vs. host disease (GVHD) is a major complication of allogeneic bone marrow transplantation (allo-BMT). Strategies to limit GVHD by selective promotion of epithelial regeneration in the absence of immunosuppression are largely unknown.
Autor:
Jarrod Dudakov, Alan Hanash, Robert Jenq, Lauren Young, Arnab Ghosh, Natalie Singer, Mallory West, Odette Smith, Amanda Holland, Jennifer Tsai, Richard Boyd, Marcel van den Brink
Publikováno v:
The Journal of Immunology. 188:44.6-44.6
Thymic regeneration is a crucial function that allows for renewal of immune competance after stress, infection or immunodepletion, however the mechanisms governing this rejuvenation remain poorly understood. Here we detail a framework of endogenous t