Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Jarrod B, French"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8834 (2023)
The suppressor of TCR signaling (Sts) proteins, Sts-1 and Sts-2, are a pair of closely related signaling molecules that belong to the histidine phosphatase (HP) family of enzymes by virtue of an evolutionarily conserved C-terminal phosphatase domain.
Externí odkaz:
https://doaj.org/article/04095c993d05415c816bf0ce0914dbf6
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Klebsiella pneumoniae is a bacterial pathogen that is increasingly responsible for hospital-acquired pneumonia and sepsis. Progressive development of antibiotic resistance has led to higher mortality rates and creates a need for novel treatments. Bec
Externí odkaz:
https://doaj.org/article/73e3f1870dc04bd28e6b2ed989503f45
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0248991 (2021)
Agmatine amidinohydrolase, or agmatinase, catalyzes the conversion of agmatine to putrescine and urea. This enzyme is found broadly across kingdoms of life and plays a critical role in polyamine biosynthesis and the regulation of agmatine concentrati
Externí odkaz:
https://doaj.org/article/d185e2f68ca3478e8deb9dc34c21ad3c
Publikováno v:
Cells, Vol 10, Iss 10, p 2603 (2021)
Nucleotides are essential to cell growth and survival, providing cells with building blocks for DNA and RNA, energy carriers, and cofactors. Mitochondria have a critical role in the production of intracellular ATP and participate in the generation of
Externí odkaz:
https://doaj.org/article/4a892da73f544fd7a79a5f8c605cd9e9
Autor:
Nick D Van Skike, Nana K Minkah, Chad H Hogan, Gary Wu, Peter T Benziger, Darby G Oldenburg, Mehmet Kara, Deborah M Kim-Holzapfel, Douglas W White, Scott A Tibbetts, Jarrod B French, Laurie T Krug
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007319 (2018)
[This corrects the article DOI: 10.1371/journal.ppat.1006843.].
Externí odkaz:
https://doaj.org/article/d55fa571fd46423cac168acc91f4ab9f
Autor:
Nick D Van Skike, Nana K Minkah, Chad H Hogan, Gary Wu, Peter T Benziger, Darby G Oldenburg, Mehmet Kara, Deborah M Kim-Holzapfel, Douglas W White, Scott A Tibbetts, Jarrod B French, Laurie T Krug
Publikováno v:
PLoS Pathogens, Vol 14, Iss 2, p e1006843 (2018)
Gammaherpesviruses encode proteins with homology to the cellular purine metabolic enzyme formyl-glycinamide-phosphoribosyl-amidotransferase (FGARAT), but the role of these viral FGARATs (vFGARATs) in the pathogenesis of a natural host has not been in
Externí odkaz:
https://doaj.org/article/b1341950bb304c61a8fd0dcb56a91ad8
Autor:
Deborah M. Kim-Holzapfel, Raja Dey, Brian C. Richardson, Danushka Arachchige, Kanamata Reddy, Humberto De Vitto, Janarjan Bhandari, Jarrod B. French
Publikováno v:
Journal of Biological Chemistry. 299:102949
Autor:
Jarrod B. French, Iva Chitrakar, Jinelle M. Wint, Stephen G. Walker, James N. Iuliano, Helena A. Woroniecka, Peter J. Tonge, Jinnette Tolentino Collado, Yong Le He
Publikováno v:
ACS Infectious Diseases. 6:2592-2603
The opportunistic human pathogen, A. baumannii, senses and responds to light using the blue light sensing A (BlsA) photoreceptor protein. BlsA is a blue-light-using flavin adenine dinucleotide (BLUF) protein that is known to regulate a wide variety o
Autor:
Ian P. Clark, Kevin H. Gardner, Helena A. Woroniecka, Igor V. Sazanovich, Andras Lukacs, Christopher R. Hall, Jinnette Tolentino Collado, James N. Iuliano, Carlos Simmerling, Katrin Adamczyk, Gregory M. Greetham, James M. Aramini, Agnieszka A. Gil, Jared E. Toettcher, Jarrod B. French, Pavithran T. Ravindran, Taraneh Daryaee, Seung Youn Shin, Stephen R. Meech, Uthama R. Edupuganti, Peter J. Tonge
Publikováno v:
ACS Chem Biol
Light-activated protein domains provide a convenient, modular, and genetically encodable sensor for optogenetics and optobiology. Although these domains have now been deployed in numerous systems, the precise mechanism of photoactivation and the acco
Publikováno v:
J Biol Chem
The suppressor of T-cell receptor (TCR) signaling (Sts) proteins Sts-1 and Sts-2 suppress receptor-mediated signaling pathways in various immune cells, including the TCR pathway in T cells and the Dectin-1 signaling pathway in phagocytes. As multidom