Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jarrell T Nelson"'
Autor:
Jennifer D Deem, Chelsea L Faber, Christian Pedersen, Bao Anh Phan, Sarah A Larsen, Kayoko Ogimoto, Jarrell T Nelson, Vincent Damian, Megan A Tran, Richard D Palmiter, Karl J Kaiyala, Jarrad M Scarlett, Michael R Bruchas, Michael W Schwartz, Gregory J Morton
Publikováno v:
eLife, Vol 9 (2020)
To maintain energy homeostasis during cold exposure, the increased energy demands of thermogenesis must be counterbalanced by increased energy intake. To investigate the neurobiological mechanisms underlying this cold-induced hyperphagia, we asked wh
Externí odkaz:
https://doaj.org/article/3bf1e03edc9c473196f7e1c90cbf2a36
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119391 (2015)
Survival of free-living animals depends on the ability to maintain core body temperature in the face of rapid and dramatic changes in their thermal environment. If food intake is not adjusted to meet the changing energy demands associated with change
Externí odkaz:
https://doaj.org/article/69968a4b36d74999925016589ae6bbee
Autor:
Karl J. Kaiyala, Jennifer D. Deem, Jarrell T. Nelson, Kevin R. Velasco, Kayoko Ogimoto, Kenjiro Muta, Gregory J. Morton
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 315:E552-E564
The ability to maintain core temperature within a narrow range despite rapid and dramatic changes in environmental temperature is essential for the survival of free-living mammals, and growing evidence implicates an important role for the hormone lep
Autor:
Karl J. Kaiyala, Jarrad M. Scarlett, Michael W. Schwartz, Chelsea L. Faber, Vincent Damian, Gregory J. Morton, Sarah A Larsen, Megan A. Tran, Christian E. Pedersen, Bao Anh Phan, Richard D. Palmiter, Kayoko Ogimoto, Jennifer D. Deem, Jarrell T. Nelson, Michael R. Bruchas
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
To maintain energy homeostasis during cold exposure, the increased energy demands of thermogenesis must be counterbalanced by increased energy intake. To investigate the neurobiological mechanisms underlying this cold-induced hyperphagia, we asked wh
Autor:
Richard N. Bergman, Karl J. Kaiyala, Steven E. Kahn, Darko Stefanovski, Miles E. Matsen, Francesca Piccinini, Gregory J. Morton, Jarrad M. Scarlett, Gerald J. Taborsky, Michael W. Schwartz, Nikhil K. Acharya, Jarrell T. Nelson, Kenjiro Muta, Jennifer M. Rojas
Publikováno v:
Diabetes
Dynamic adjustment of insulin secretion to compensate for changes of insulin sensitivity that result from alteration of nutritional or metabolic status is a fundamental aspect of glucose homeostasis. To investigate the role of the brain in this coupl
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 5, Iss 10, Pp 892-902 (2016)
Molecular Metabolism, Vol 5, Iss 10, Pp 892-902 (2016)
Objective To investigate the role played by leptin in thermoregulation, we studied the effects of physiological leptin replacement in leptin-deficient ob/ob mice on determinants of energy balance, thermogenesis and heat retention under 3 different am
Autor:
Jarrell T. Nelson, Gregory J. Morton, Bao Anh N. Phan, Jennifer D. Deem, Vincent Damian, Michael W. Schwartz, Kevin R. Velasco, Kayoko Ogimoto
Publikováno v:
Diabetes. 68
The adaptive response to cold exposure includes matched increases of both energy expenditure (to support thermogenesis) and energy intake, enabling core temperature to be maintained with no change of body fat stores. To investigate whether activation
Autor:
Jarrell T. Nelson, Kayoko Ogimoto, Kevin R. Velasco, Jennifer D. Deem, Zachary A. Knight, Michael W. Schwartz, Gregory J. Morton, Bao Anh N. Phan, Vincent Damian
Publikováno v:
Diabetes. 67
Inhibition of warm sensitive neurons (WSN) in the hypothalamic preoptic area (POA) has been suggested to play a key role in the thermogenic response to cold exposure. As this response is enabled by a marked increase of insulin sensitivity in thermoge
Autor:
Stephan J. Guyenet, Mauricio D. Dorfman, Jarrell T. Nelson, Miles E. Matsen, Jarrad M. Scarlett, Joshua P. Thaler, Hong T. Nguyen, Thomas H. Meek, Michael W. Schwartz, David P. Olson, Margaret B. Allison, Gregory J. Morton, Vincent Damian, Martin G. Myers
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(14)
Previous studies implicate the hypothalamic ventromedial nucleus (VMN) in glycemic control. Here, we report that selective inhibition of the subset of VMN neurons that express the transcription factor steroidogenic-factor 1 (VMN(SF1) neurons) blocks
Autor:
Kayoko Ogimoto, Tami Wolden-Hanson, Jarrell T. Nelson, James E. Blevins, James L. Graham, Bang H. Hwang, Benjamin W. Thompson, Karl J. Kaiyala, Peter J. Havel, Zachary S. Roberts, Michael W. Schwartz, Gregory J. Morton, Jacqueline M. Ho, Denis G. Baskin, Vishwanath T. Anekonda, Karen L. Bales
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 310(7)
Based largely on a number of short-term administration studies, growing evidence suggests that central oxytocin is important in the regulation of energy balance. The goal of the current work is to determine whether long-term third ventricular (3V) in