Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jaroslaw W. Żmijewski"'
Autor:
Eugene Becker, Maroof Husain, Nathaniel Bone, Samuel Smith, Peter Morris, Jaroslaw W. Zmijewski
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Bacterial pneumonia and related lung injury are among the most frequent causes of mortality in intensive care units, but also inflict serious and prolonged respiratory complications among survivors. Given that endoplasmic reticulu
Externí odkaz:
https://doaj.org/article/976cecc335274dfc80152cedac53ca22
Publikováno v:
Gene. 223:293-302
The class-IIS restriction endonuclease, R.MmeI, was isolated from Methylophilus methylotrophus. It was originally described as a monomeric enzyme, with the native Mr 105 000±7000, which did not cleave DNA efficiently [Boyd et al. (1986) Nucleic Acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3273a995b1f17ae649d756046c6ded43
https://doi.org/10.1016/s0378-1119(98)00450-8
https://doi.org/10.1016/s0378-1119(98)00450-8
Autor:
Tapasi Rana, Chunsun Jiang, Sami Banerjee, Nengjun Yi, Jaroslaw W. Zmijewski, Gang Liu, Rui-Ming Liu
Publikováno v:
Cells, Vol 12, Iss 15, p 2008 (2023)
Cellular senescence contributes importantly to aging and aging-related diseases, including idiopathic pulmonary fibrosis (IPF). Alveolar epithelial type II (ATII) cells are progenitors of alveolar epithelium, and ATII cell senescence is evident in IP
Externí odkaz:
https://doaj.org/article/6b040f7b3355402e8f456e3b845966cb
Autor:
Nathaniel B. Bone, Eugene J. Becker, Maroof Husain, Shaoning Jiang, Anna A. Zmijewska, Dae-Won Park, Balu Chacko, Victor Darley-Usmar, Murielle Grégoire, Jean-Marc Tadie, Victor J. Thannickal, Jaroslaw W. Zmijewski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Metabolic and bioenergetic plasticity of immune cells is essential for optimal responses to bacterial infections. AMPK and Parkin ubiquitin ligase are known to regulate mitochondrial quality control mitophagy that prevents unwanted inflammat
Externí odkaz:
https://doaj.org/article/721d2c15ada041d197bf848bf5d4bb98
Autor:
Ranu Surolia, Fu Jun Li, Zheng Wang, Mahendra Kashyap, Ritesh Kumar Srivastava, Amie M. Traylor, Pooja Singh, Kevin G. Dsouza, Harrison Kim, Jean-Francois Pittet, Jaroslaw W. Zmijewski, Anupam Agarwal, Mohammad Athar, Aftab Ahmad, Veena B. Antony
Publikováno v:
JCI Insight, Vol 6, Iss 10 (2021)
Despite the high morbidity and mortality among patients with extensive cutaneous burns in the intensive care unit due to the development of acute respiratory distress syndrome, effective therapeutics remain to be determined. This is primarily because
Externí odkaz:
https://doaj.org/article/11229075bb154bd8907ed402be32ccab
Autor:
Maroof Husain, Eugene J. Becker, Jr., Nathaniel B. Bone, Amy Schmitt, Jean-Francois Pittet, Jaroslaw W. Zmijewski
Publikováno v:
Redox Biology, Vol 36, Iss , Pp 101651- (2020)
Trauma and sepsis are frequent causes of immunosuppression and risk of secondary bacterial infections and mortality among critically ill patients. Reduced activity of neutrophil NADPH oxidase 2 (NOX2) and impaired bacterial killing are among the majo
Externí odkaz:
https://doaj.org/article/3fc45299a1494c6c8a454717fdf1b05a
Autor:
Dae Won Park, Shaoning Jiang, Jean-Marc Tadie, William S. Stigler, Yong Gao, Jessy Deshane, Edward Abraham, Jaroslaw W. Zmijewski
Publikováno v:
Molecular Medicine, Vol 19, Iss 1, Pp 387-398 (2013)
Abstract An inability of neutrophils to eliminate invading microorganisms is frequently associated with severe infection and may contribute to the high mortality rates associated with sepsis. In the present studies, we examined whether metformin and
Externí odkaz:
https://doaj.org/article/10357f9ee8764c019d1f5f4494f2f16e
Autor:
Jean-François Pittet, Hidefumi Koh, Xiaohui Fang, Karen Iles, Sarah Christiaans, Naseem Anjun, Brant M. Wagener, Dae Won Park, Jaroslaw W. Zmijewski, Michael A. Matthay, Jérémie Roux
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/cabda09a3884455fb8ad23c9dc08f114