Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Jaroslaw W, Zmijewski"'
Autor:
Eugene Becker, Maroof Husain, Nathaniel Bone, Samuel Smith, Peter Morris, Jaroslaw W. Zmijewski
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Bacterial pneumonia and related lung injury are among the most frequent causes of mortality in intensive care units, but also inflict serious and prolonged respiratory complications among survivors. Given that endoplasmic reticulu
Externí odkaz:
https://doaj.org/article/976cecc335274dfc80152cedac53ca22
Autor:
Tapasi Rana, Chunsun Jiang, Sami Banerjee, Nengjun Yi, Jaroslaw W. Zmijewski, Gang Liu, Rui-Ming Liu
Publikováno v:
Cells, Vol 12, Iss 15, p 2008 (2023)
Cellular senescence contributes importantly to aging and aging-related diseases, including idiopathic pulmonary fibrosis (IPF). Alveolar epithelial type II (ATII) cells are progenitors of alveolar epithelium, and ATII cell senescence is evident in IP
Externí odkaz:
https://doaj.org/article/6b040f7b3355402e8f456e3b845966cb
Autor:
Nathaniel B. Bone, Eugene J. Becker, Maroof Husain, Shaoning Jiang, Anna A. Zmijewska, Dae-Won Park, Balu Chacko, Victor Darley-Usmar, Murielle Grégoire, Jean-Marc Tadie, Victor J. Thannickal, Jaroslaw W. Zmijewski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Metabolic and bioenergetic plasticity of immune cells is essential for optimal responses to bacterial infections. AMPK and Parkin ubiquitin ligase are known to regulate mitochondrial quality control mitophagy that prevents unwanted inflammat
Externí odkaz:
https://doaj.org/article/721d2c15ada041d197bf848bf5d4bb98
Autor:
Diptiman Chanda, Mohammad Rehan, Samuel R Smith, Kevin G Dsouza, Yong Wang, Karen Bernard, Deepali Kurundkar, Vinayak Memula, Kyoko Kojima, James A Mobley, Gloria A Benavides, Victor Darley-Usmar, Young-iL Kim, Jaroslaw W Zmijewski, Jessy S Deshane, Stijn De Langhe, Victor J Thannickal
Publikováno v:
eLife, Vol 10 (2021)
Multicellular organisms maintain structure and function of tissues/organs through emergent, self-organizing behavior. In this report, we demonstrate a critical role for lung mesenchymal stromal cell (L-MSC) aging in determining the capacity to form t
Externí odkaz:
https://doaj.org/article/ef49c5e79b324a57988570b54d4ab9ff
Autor:
Ranu Surolia, Fu Jun Li, Zheng Wang, Mahendra Kashyap, Ritesh Kumar Srivastava, Amie M. Traylor, Pooja Singh, Kevin G. Dsouza, Harrison Kim, Jean-Francois Pittet, Jaroslaw W. Zmijewski, Anupam Agarwal, Mohammad Athar, Aftab Ahmad, Veena B. Antony
Publikováno v:
JCI Insight, Vol 6, Iss 10 (2021)
Despite the high morbidity and mortality among patients with extensive cutaneous burns in the intensive care unit due to the development of acute respiratory distress syndrome, effective therapeutics remain to be determined. This is primarily because
Externí odkaz:
https://doaj.org/article/11229075bb154bd8907ed402be32ccab
Autor:
Maroof Husain, Eugene J. Becker, Jr., Nathaniel B. Bone, Amy Schmitt, Jean-Francois Pittet, Jaroslaw W. Zmijewski
Publikováno v:
Redox Biology, Vol 36, Iss , Pp 101651- (2020)
Trauma and sepsis are frequent causes of immunosuppression and risk of secondary bacterial infections and mortality among critically ill patients. Reduced activity of neutrophil NADPH oxidase 2 (NOX2) and impaired bacterial killing are among the majo
Externí odkaz:
https://doaj.org/article/3fc45299a1494c6c8a454717fdf1b05a
Autor:
Wei-Xing Zong, Victor M. Darley-Usmar, Eugene J. Becker, Jason Craver, Xiaosen Ouyang, Jianhua Zhang, Jaroslaw W. Zmijewski, Nathaniel B. Bone, Michelle S. Johnson
Publikováno v:
Laboratory Investigation. 101:1467-1474
The mortality rates among patients who initially survive sepsis are, in part, associated with a high risk of secondary lung infections and respiratory failure. Given that phagolysosomes are important for intracellular killing of pathogenic microbes,
Background Bacterial pneumonia and related lung injury are among the most frequent causes of mortality in intensive care units, but also inflict serious and prolonged respiratory complications among survivors. Given that endoplasmic reticulum (ER) st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a3de71b4fcb72ba6c5a3c0ddf37ec15
https://doi.org/10.21203/rs.3.rs-2338974/v1
https://doi.org/10.21203/rs.3.rs-2338974/v1
Publikováno v:
American journal of respiratory cell and molecular biology. 68(1)
Publikováno v:
American journal of respiratory cell and molecular biology.