Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Jaroslaw Slawek"'
Autor:
Patrycja Maszka, Magdalena Kwasniak-Butowska, Dominik Cysewski, Jaroslaw Slawek, Ryszard T. Smolenski, Marta Tomczyk
Publikováno v:
Metabolites, Vol 13, Iss 3, p 369 (2023)
The prevalence of neurodegenerative diseases (NDs) is increasing due to the aging population and improved longevity. They are characterized by a range of pathological hallmarks, including protein aggregation, mitochondrial dysfunction, and oxidative
Externí odkaz:
https://doaj.org/article/4db22ab966c246cabf0f46981740fede
Autor:
Wolfgang H. Jost, Tobias Bäumer, Rainer Laskawi, Jaroslaw Slawek, Björn Spittau, Armin Steffen, Martin Winterholler, Ganesh Bavikatte
Publikováno v:
Neurology and Therapy, Vol 8, Iss 2, Pp 273-288 (2019)
Abstract Botulinum neurotoxin (BoNT) is considered the treatment of choice for various symptoms and diseases such as focal dystonia and focal spasticity. The effects of BoNT on the salivary glands have also been known for years, but their use was lim
Externí odkaz:
https://doaj.org/article/3da5fdc73a944477bc43f53688a92ded
Autor:
Lukasz M. Milanowski, Xu Hou, Jenny M. Bredenberg, Fabienne C. Fiesel, Liam T. Cocker, Alexandra I. Soto-Beasley, Ronald L. Walton, Audrey J. Strongosky, Ayman H. Faroqi, Maria Barcikowska, Magdalena Boczarska-Jedynak, Jaroslaw Dulski, Lyuda Fedoryshyn, Piotr Janik, Anna Potulska-Chromik, Katherine Karpinsky, Anna Krygowska-Wajs, Tim Lynch, Diana A. Olszewska, Grzegorz Opala, Aleksander Pulyk, Irena Rektorova, Yanosh Sanotsky, Joanna Siuda, Mariusz Widlak, Jaroslaw Slawek, Monika Rudzinska-Bar, Ryan Uitti, Monika Figura, Stanislaw Szlufik, Sylwia Rzonca-Niewczas, Elzbieta Podgorska, Pamela J. McLean, Dariusz Koziorowski, Owen A. Ross, Dorota Hoffman-Zacharska, Wolfdieter Springer, Zbigniew K. Wszolek
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7086 (2022)
Parkinson’s disease (PD) is generally considered a sporadic disorder, but a strong genetic background is often found. The aim of this study was to identify the underlying genetic cause of PD in two affected siblings and to subsequently assess the r
Externí odkaz:
https://doaj.org/article/ea0f2ba3ea554500ae31bda32d14847a
Autor:
Paulina Bastian, Jaroslaw Dulski, Anna Roszmann, Dagmara Jacewicz, Alicja Kuban-Jankowska, Jaroslaw Slawek, Michal Wozniak, Magdalena Gorska-Ponikowska
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 248 (2021)
Mitochondria, as “power house of the cell”, are crucial players in cell pathophysiology. Beyond adenosine triphosphate (ATP) production, they take part in a generation of reactive oxygen species (ROS), regulation of cell signaling and cell death.
Externí odkaz:
https://doaj.org/article/7758c4ddc86a4292903c75390bf1a258
Autor:
Selina Wray, Matthew Self, NINDS Parkinson's Disease iPSC Consortium, NINDS Huntington's Disease iPSC Consortium, NINDS ALS iPSC Consortium, Patrick A Lewis, Jan-Willem Taanman, Natalie S Ryan, Colin J Mahoney, Yuying Liang, Michael J Devine, Una-Marie Sheerin, Henry Houlden, Huw R Morris, Daniel Healy, Jose-Felix Marti-Masso, Elisavet Preza, Suzanne Barker, Margaret Sutherland, Roderick A Corriveau, Michael D'Andrea, Anthony H V Schapira, Ryan J Uitti, Mark Guttman, Grzegorz Opala, Barbara Jasinska-Myga, Andreas Puschmann, Christer Nilsson, Alberto J Espay, Jaroslaw Slawek, Ludwig Gutmann, Bradley F Boeve, Kevin Boylan, A Jon Stoessl, Owen A Ross, Nicholas J Maragakis, Jay Van Gerpen, Melissa Gerstenhaber, Katrina Gwinn, Ted M Dawson, Ole Isacson, Karen S Marder, Lorraine N Clark, Serge E Przedborski, Steven Finkbeiner, Jeffrey D Rothstein, Zbigniew K Wszolek, Martin N Rossor, John Hardy
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43099 (2012)
Our understanding of the molecular mechanisms of many neurological disorders has been greatly enhanced by the discovery of mutations in genes linked to familial forms of these diseases. These have facilitated the generation of cell and animal models
Externí odkaz:
https://doaj.org/article/9a35e1d7ec9b460c9b9c8d8637a681ec
Autor:
Anna Stanisławska-Sachadyn, Michał Krzemiński, Daniel Zielonka, Magdalena Krygier, Ewa Ziętkiewicz, Jarosław Sławek, Janusz Limon, REGISTRY investigators of the European Huntington’s Disease Network (EHDN)
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Huntington’s disease (HD) is a hereditary neurodegenerative disorder caused by the extension of the CAG repeats in exon 1 of the HTT gene and is transmitted in a dominant manner. The present study aimed to assess whether patients’ sex, i
Externí odkaz:
https://doaj.org/article/db3578da0e7b45379158dc3931e941c0
Autor:
Jaroslaw Slawek
Publikováno v:
European journal of pain (London, England)REFERENCES. 26(6)
Autor:
Jaroslaw Slawek, Peter McAllister, Sebastian Paus, Daniel Truong, Todd M. Gross, Roman G. Rubio, Pat Kesslak, Domenico Vitarella
Publikováno v:
Toxicon. 214:S50-S51
Autor:
Michal Nowicki, Monika Komar, Mariusz Kusztal, Tomasz Liberek, Katarzyna Mizia-Stec, Jolanta Malyszko, Katarzyna Muras-Szwedziak, Krzysztof Pawlaczyk, Piotr Podolec, Jaroslaw Slawek
Survey to Fabry Research Letter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b7480315b7df8879058eff1599f0c8
Autor:
Michał Nowicki, Stanisława Bazan-Socha, Beata Błażejewska-Hyżorek, Mariusz M. Kłopotowski, Monika Komar, Mariusz A. Kusztal, Tomasz Liberek, Jolanta Małyszko, Katarzyna Mizia-Stec, Zofia Oko-Sarnowska, Krzysztof Pawlaczyk, Piotr Podolec, Jarosław Sławek, on behalf of the Polish Fabry Disease Collaborative Group
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Fabry disease (FD) is a rare, X-linked lysosomal storage disorder affecting both males and females caused by genetic abnormalities in the gene encoding the enzyme α-galactosidase A. FD-affected patients represent a highly variable clinical
Externí odkaz:
https://doaj.org/article/6eb1ebc51ef24c4782f51c05363cee95