Zobrazeno 1 - 10
of 1 174
pro vyhledávání: '"Jaroslaw P, Maciejewski"'
Autor:
Naomi Kawashima, Yasuo Kubota, Carlos Bravo-Perez, Luca Guarnera, Nakisha D. Williams, Arda Durmaz, Michaela Witt, Arooj Ahmed, Carmelo Gurnari, Jaroslaw P. Maciejewski, Valeria Visconte
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-6 (2024)
Abstract DNA methyltransferase 3 A mutations (DNMT3A MT) are frequent in myeloid neoplasia (MN) and mostly heterozygous. However, cases with multiple DNMT3A MT can be also encountered but their clinical and genetic landscape remains unexplored. We re
Externí odkaz:
https://doaj.org/article/eb8828e15ae0440189a9cfafde31b70a
Autor:
Jaymeson Gordon, Carlos Bravo-Perez, Luca Guarnera, Serhan Unlu, Naomi Kawashima, Arooj Ahmed, Christopher Haddad, Yasuo Kubota, Ishani Nautiyal, Fauzia Ullah, Danai Dima, Nakisha D. Williams, Tariq Kewan, Waled Bahaj, Hetty E. Carraway, Chao-Yie Yang, Carmelo Gurnari, Valeria Visconte, Jaroslaw P. Maciejewski
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/5ac3055fb4da4ce3afb8ec78e891a1df
Autor:
Yasuo Kubota, Xiaorong Gu, Laila Terkawi, Juraj Bodo, Bartlomiej P. Przychodzen, Hussein Awada, Nakisha Williams, Carmelo Gurnari, Naomi Kawashima, Mai Aly, Arda Durmaz, Minako Mori, Ben Ponvilawan, Tariq Kewan, Waled Bahaj, Manja Meggendorfer, Babal K. Jha, Valeria Visconte, Heesun J. Rogers, Torsten Haferlach, Jaroslaw P. Maciejewski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract PHF6 mutations (PHF6 MT) are identified in various myeloid neoplasms (MN). However, little is known about the precise function and consequences of PHF6 in MN. Here we show three main findings in our comprehensive genomic and proteomic study.
Externí odkaz:
https://doaj.org/article/a86ae8fe55bc46c2af1a9650289584f9
Autor:
Waled Bahaj, Tariq Kewan, Carmelo Gurnari, Arda Durmaz, Ben Ponvilawan, Ishani Pandit, Yasuo Kubota, Olisaemeka D. Ogbue, Misam Zawit, Yazan Madanat, Taha Bat, Suresh K. Balasubramanian, Hussein Awada, Ramsha Ahmed, Minako Mori, Manja Meggendorfer, Torsten Haferlach, Valeria Visconte, Jaroslaw P. Maciejewski
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Background TP53 mutations (TP53 MT ) occur in diverse genomic configurations. Particularly, biallelic inactivation is associated with poor overall survival in cancer. Lesions affecting only one allele might not be directly leukemogenic, ques
Externí odkaz:
https://doaj.org/article/be24204f0e834aaeb1aa9535926fa7e7
Autor:
Tariq Kewan, Arda Durmaz, Waled Bahaj, Carmelo Gurnari, Laila Terkawi, Hussein Awada, Olisaemeka D. Ogbue, Ramsha Ahmed, Simona Pagliuca, Hassan Awada, Yasuo Kubota, Minako Mori, Ben Ponvilawan, Bayan Al-Share, Bhumika J. Patel, Hetty E. Carraway, Jacob Scott, Suresh K. Balasubramanian, Taha Bat, Yazan Madanat, Mikkael A. Sekeres, Torsten Haferlach, Valeria Visconte, Jaroslaw P. Maciejewski
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Genomic mutations drive the pathogenesis of myelodysplastic syndromes and acute myeloid leukemia. While morphological and clinical features have dominated the classical criteria for diagnosis and classification, incorporation of molecular da
Externí odkaz:
https://doaj.org/article/6c02bbbd75f840c28ae20ecd4c63c506
Autor:
Simona Pagliuca, Carmelo Gurnari, Colin Hercus, Sébastien Hergalant, Sanghee Hong, Adele Dhuyser, Maud D’Aveni, Alice Aarnink, Marie Thérèse Rubio, Pierre Feugier, Francesca Ferraro, Hetty E. Carraway, Ronald Sobecks, Betty K. Hamilton, Navneet S. Majhail, Valeria Visconte, Jaroslaw P. Maciejewski
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Graft-versus-leukemia (GvL) reactions are responsible for the effectiveness of allogeneic hematopoietic cell transplantation as a treatment modality for myeloid neoplasia, whereby donor T- effector cells recognize leukemia neoantigens. Howev
Externí odkaz:
https://doaj.org/article/8c1bcd077dcf4d8795e32c0ba12bd5cc
Autor:
Olisaemeka D. Ogbue, Tariq Kewan, Waled S. Bahaj, Carmelo Gurnari, Valeria Visconte, Jaroslaw P. Maciejewski
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-5 (2023)
Abstract Isolated chronic idiopathic neutropenia (CIN) is a rare disease with multiple contributing etiologies that must be ruled out before establishing a diagnosis. We studied clinical and molecular data of 238 consecutive adult patients with CIN.
Externí odkaz:
https://doaj.org/article/612e6e01243c461b87c97402452f11dd
Autor:
Carmelo Gurnari, Alfonso Piciocchi, Stefano Soddu, Fabrizio Bonanni, Emilia Scalzulli, Pasquale Niscola, Ambra Di Veroli, Anna Lina Piccioni, Monica Piedimonte, Gianluca Maiorana, Prassede Salutari, Laura Cicconi, Michelina Santopietro, Svitlana Gumenyuk, Chiara Sarlo, Susanna Fenu, Agostino Tafuri, Roberto Latagliata, Luana Fianchi, Marianna Criscuolo, Jaroslaw P. Maciejewski, Luca Maurillo, Francesco Buccisano, Massimo Breccia, Maria Teresa Voso
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 9, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/759915887e3a46a78ef746c6aec9862d
Autor:
Jani Huuhtanen, Sofie Lundgren, Mikko Keränen, Xingim Feng, Alina Dulau-Florea, Bhavisha Patel, Yoshitaka Zaimoku, Cassandra Kerr, Emmi Jokinen, Markus Heinonen, Hanna Rajala, Sanna Siitonen, Freja Ebeling, Georgina Ryland, Lucy Fox, Piers Blombery, Eva Hellström-Lindberg, Jaroslaw P. Maciejewski, Neal S. Young, Harri Lähdesmäki, Satu Mustjoki
Publikováno v:
HemaSphere, Vol 7, p e2285644 (2023)
Externí odkaz:
https://doaj.org/article/e86b35d4b8084784b622157a832f1600
Autor:
Antonio Maria Risitano, Alexander Röth, Austin Kulasekararaj, Phillip Scheinberg, Yasutaka Ueda, Carlos de Castro, Eros DI Bona, Morag Griffin, Saskia Langemeijer, Hubert Schrezenmeier, Wilma Barcellini, Vitor Aq Mauad, Jens Panse, Philippe Schafhausen, Suzanne Tavitian, Eloise Beggiato, Anna Gaya, Wei-Han Huang, Toshio Kitawaki, Abdullah Kutlar, Jaroslaw P Maciejewski, Rosario Notaro, Vinod Pullarkat, Jörg Schubert, Louis Terriou, Michihiro Uchiyama, Flore Sicre de Fontbrune, Luana Marano, Ferras Alashkar, Shreyans Gandhi, Cécile Kerloëguen, Rakesh Kumar, Christine Thorburn, Samopriyo Maitra, Marion Dahlke, Régis Peffault de Latour
Publikováno v:
HemaSphere, Vol 7, p e29006c9 (2023)
Externí odkaz:
https://doaj.org/article/efa1233f722549f49a84c98218df9720