Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jaroslaw Kanski"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 288:H371-H381
Proteomic techniques were used to identify cardiac proteins from whole heart homogenate and heart mitochondria of Fisher 344/Brown Norway F1 rats, which suffer protein nitration as a consequence of biological aging. Soluble proteins from young (5 mo
Publikováno v:
Brain Research. 988:173-179
Inhibiting aggregation and deposition of amyloid beta-peptide (Abeta) in brain is a therapeutic strategy for Alzheimer's disease (AD). A Congo-red-like molecule, X-34, is reported to bind to Abeta deposits. Oxidative stress associated with Abeta is h
Publikováno v:
Free Radical Biology and Medicine. 32:1205-1211
Alzheimer’s disease (AD) brain is characterized by excess deposition of the 42-amino acid amyloid β-peptide [Aβ(1–42)]. AD brain is under intense oxidative stress, and we have previously suggested that Aβ(1–42) was associated with this incre
Autor:
Janna M. Hackett, Jaroslaw Kanski, Mark S. Kindy, D. Allan Butterfield, Christopher M. Lauderback, Noboyo Maeda
Publikováno v:
Brain Research. 924:90-97
Several functional differences have been reported among the three human e2, e3, and e4 alleles of apolipoprotein E (apoE). One functional difference lies in the antioxidant potential of these alleles; e4 has the poorest potential. Interestingly, e4 a
Publikováno v:
Neurochemical Research. 26:23-29
The antioxidant properties of 5-aminosalicylic acid in vitro were evaluated in a synaptosomal membrane system prepared from gerbil cortical synaptosomes using EPR spin labeling and spectroscopic techniques. MAL-6 (2,2,6,6-tetramethyl-4-maleimidopiper
Publikováno v:
Analytical Letters. 32:1183-1192
Peroxynitrite-induced oxidative stress was investigated in red blood cells by luminol-dependent chemiluminescence. Red blood cells are susceptible to free radical damage due to the abundance of oxygen, presence of iron and other agents such as polyun
Autor:
Marina V. Aksenova, D. Allan Butterfield, Sridhar Varadarajan, Jaroslaw Kanski, Christopher M. Lauderback
Publikováno v:
ChemInform. 32
Oxidative stress induced by amyloid ‚-peptide (A‚) has been implicated in the neurodegeneration observed in Alzheimer's disease (AD) brain. However, the mechanism by which the predominant form of A‚ found in AD brains, A‚(1-42), causes oxidat
Autor:
Rukhsana Sultana, Giovanni Pennisi, Maria Sapienza, Rita Bella, E Guagliano, Giovanni Scapagnini, Jaroslaw Kanski, Anna Maria Giuffrida Stella, Vittorio Calabrese, Cesare Mancuso, D. A. Butterfield
Publikováno v:
Scopus-Elsevier
Antioxidants & redox signalling 8 (2006): 1975–1986.
info:cnr-pdr/source/autori:Calabrese V, Sultana R, Scapagnini G, Guagliano E, Sapienza M, Bella R, Kanski J, Pennisi G, Mancuso C, Stella AM, Butterfield DA./titolo:Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease./doi:/rivista:Antioxidants & redox signalling/anno:2006/pagina_da:1975/pagina_a:1986/intervallo_pagine:1975–1986/volume:8
Antioxidants & redox signalling 8 (2006): 1975–1986.
info:cnr-pdr/source/autori:Calabrese V, Sultana R, Scapagnini G, Guagliano E, Sapienza M, Bella R, Kanski J, Pennisi G, Mancuso C, Stella AM, Butterfield DA./titolo:Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease./doi:/rivista:Antioxidants & redox signalling/anno:2006/pagina_da:1975/pagina_a:1986/intervallo_pagine:1975–1986/volume:8
Alzheimer's disease (AD) is a neurodegenerative disorder with cognitive and memory decline, personality changes, and synapse loss. Increasing evidence indicates that factors such as oxidative and nitrosative stress, glutathione depletion, and impaire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31ea631d625276dae5670914ce61cbce
http://hdl.handle.net/11695/3117
http://hdl.handle.net/11695/3117
Publikováno v:
Experimental gerontology. 41(4)
We identified age-dependent post-translational modifications of skeletal muscle glycogen phosphorylase b (Ph-b), isolated from F1 hybrids of Fisher 344×Brown Norway rats. Ph-b isolated from 34 months old rats showed a statistically significant decre
Autor:
Jaroslaw, Kanski, Christian, Schöneich
Publikováno v:
Methods in enzymology. 396
Proteomic techniques for the identification of 3-nitrotyrosine-containing proteins in various biological systems are described with emphasis on the direct mass spectrometric detection and sequencing of 3-nitrotyrosine-containing peptides. Strengths a