Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jaroslaw, Dastych"'
Autor:
Magdalena Boncler, Jacek Golanski, Magdalena Lukasiak, Malgorzata Redzynia, Jaroslaw Dastych, Cezary Watala
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0180022 (2017)
The toxicity of in vitro tested compounds is usually evaluated based on AC50 values calculated from dose-response curves. However, there is a large group of compounds for which a standard four-parametric sigmoid curve fitting may be inappropriate for
Externí odkaz:
https://doaj.org/article/b509b1af9fe74aee8a99973ba2a4d8cd
Autor:
Marta Borowiec, Michal Gorzkiewicz, Joanna Grzesik, Aurelia Walczak-Drzewiecka, Anna Salkowska, Ewelina Rodakowska, Kamil Steczkiewicz, Leszek Rychlewski, Jaroslaw Dastych, Krzysztof Ginalski
Publikováno v:
Toxins, Vol 8, Iss 11, p 321 (2016)
Exotoxin A (PE) from Pseudomonas aeruginosa is a bacterial ADP-ribosyltransferase, which can permanently inhibit translation in the attacked cells. Consequently, this toxin is frequently used in immunotoxins for targeted cancer therapies. In this stu
Externí odkaz:
https://doaj.org/article/be8495e1145040e08ea0bf1ad16657c1
Autor:
Ewelina, Rodakowska, Aurelia, Walczak-Drzewiecka, Marta, Borowiec, Michal, Gorzkiewicz, Joanna, Grzesik, Marcin, Ratajewski, Michal, Rozanski, Jaroslaw, Dastych, Krzysztof, Ginalski, Leszek, Rychlewski
Publikováno v:
Oncology Letters
Glypican-3 (GPC3) is a cell membrane glycoprotein that regulates cell growth and proliferation. Aberrant expression or distribution of GPC3 underlies developmental abnormalities and the development of solid tumours. The strongest evidence for the par