Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Jaroslav Janda"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
During an episode of acute kidney injury (AKI), a sudden and rapid decline in renal function is often accompanied by a persistent reduction in mitochondrial function, microvasculature dysfunction/rarefaction, and tubular epithelial injury/necrosis. A
Externí odkaz:
https://doaj.org/article/0eeb98bfa7d84d66bc9386894790b4bf
Autor:
Qing-Jun Luo, Manoj P Samanta, Fatih Köksal, Jaroslav Janda, David W Galbraith, Casey R Richardson, Fangqian Ou-Yang, Christopher D Rock
Publikováno v:
PLoS Genetics, Vol 5, Iss 4, p e1000457 (2009)
Antisense transcription is a pervasive phenomenon, but its source and functional significance is largely unknown. We took an expression-based approach to explore microRNA (miRNA)-related antisense transcription by computational analyses of published
Externí odkaz:
https://doaj.org/article/a394e19cfe7d41c2898066f1c889b15c
Publikováno v:
American Journal of Physiology-Renal Physiology. 324:F56-F63
AKI pathology involves a rapid decline in kidney function and occurs in 8–16% of hospitalized patients. There is currently no therapeutic for AKI. AKI results in mitochondria dysfunction, microvasculature injury, and loss of renal tubular function.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6efe5970cf88fe0a5dbe4686933bcf
https://doi.org/10.1152/ajprenal.00249.2022
https://doi.org/10.1152/ajprenal.00249.2022
Publikováno v:
Kidney International. 102:1073-1089
The β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aebc674541f4c828eb277ecd8e600da
https://doi.org/10.1016/j.kint.2022.05.032
https://doi.org/10.1016/j.kint.2022.05.032
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Cardiovascular Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e2d178d3ede4ee110902360232c649f
https://doi.org/10.1124/jpet.122.244110
https://doi.org/10.1124/jpet.122.244110
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Cardiovascular Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e118b4ec7806b2e77282e5f6a5141a9f
https://doi.org/10.1124/jpet.122.167030
https://doi.org/10.1124/jpet.122.167030
Autor:
G. Timothy Bowden, David S. Alberts, Zigang Dong, Ann M. Bode, Chengcheng Hu, Kathylynn Saboda, Clara Curiel-Lewandrowski, Steven P. Stratton, Jesse E. Dickinson, Janine Einspahr, Valerie S. Calvert, Emanuel F. Petricoin, Christy Barber, Zhonglin Liu, Erik R. Olson, Karen Blohm-Mangone, Jane Criswell, Jaroslav Janda, Sally E. Dickinson
The PI3Kinase/Akt/mTOR pathway has important roles in cancer development for multiple tumor types, including UV-induced nonmelanoma skin cancer. Immunosuppressed populations are at increased risk of aggressive cutaneous squamous cell carcinoma (SCC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6df9fccf19b0cff22118b6a5f393eba6
https://doi.org/10.1158/1940-6207.c.6547411.v1
https://doi.org/10.1158/1940-6207.c.6547411.v1
Autor:
Sally E. Dickinson, Georg T. Wondrak, David S. Alberts, Clara Curiel-Lewandrowski, Valerie S. Calvert, Emanuel F. Petricoin, Ann M. Bode, Zigang Dong, Denise J. Roe, Kathylynn Saboda, Michelle McComas, Jaroslav Janda, Brenda Ho, Alhassan Aodah, Paul B. Myrdal, Shekha Tahsin, Nichole B. Burkett, Karen Blohm-Mangone
An urgent need exists for the development of more efficacious molecular strategies targeting nonmelanoma skin cancer (NMSC), the most common malignancy worldwide. Inflammatory signaling downstream of Toll-like receptor 4 (TLR4) has been implicated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ab1df0b17342ac9790700dc4449eb00
https://doi.org/10.1158/1940-6207.c.6547552.v1
https://doi.org/10.1158/1940-6207.c.6547552.v1
Autor:
Sally E. Dickinson, Georg T. Wondrak, David S. Alberts, Clara Curiel-Lewandrowski, Valerie S. Calvert, Emanuel F. Petricoin, Ann M. Bode, Zigang Dong, Denise J. Roe, Kathylynn Saboda, Michelle McComas, Jaroslav Janda, Brenda Ho, Alhassan Aodah, Paul B. Myrdal, Shekha Tahsin, Nichole B. Burkett, Karen Blohm-Mangone
Staining for Ki67 in mouse tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbf35fdb17741bec306dc34cad000c2
https://doi.org/10.1158/1940-6207.22534564
https://doi.org/10.1158/1940-6207.22534564
Autor:
G. Timothy Bowden, David S. Alberts, Zigang Dong, Ann M. Bode, Chengcheng Hu, Kathylynn Saboda, Clara Curiel-Lewandrowski, Steven P. Stratton, Jesse E. Dickinson, Janine Einspahr, Valerie S. Calvert, Emanuel F. Petricoin, Christy Barber, Zhonglin Liu, Erik R. Olson, Karen Blohm-Mangone, Jane Criswell, Jaroslav Janda, Sally E. Dickinson
Schema representing UV-induced signaling, rapamycin and PHT-427-regulated pathways in keratinocytes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301db922cffaaf2f15b06bc176fc97a0
https://doi.org/10.1158/1940-6207.22534219.v1
https://doi.org/10.1158/1940-6207.22534219.v1