Zobrazeno 1 - 10
of 390
pro vyhledávání: '"Jaroslav A, Hubacek"'
Publikováno v:
International Journal of Infectious Diseases, Vol 148, Iss , Pp 107232- (2024)
Objectives: COVID-19 caused a global pandemic with millions of deaths. Fat mass and obesity-associated gene (FTO) (alias m6A RNA demethylase) and its functional rs17817449 polymorphism are candidates to influence COVID-19-associated mortality since m
Externí odkaz:
https://doaj.org/article/327bbbca361f43e6bc6e32adb7b899a6
Autor:
Jaroslav A. Hubacek, Vera Adamkova, Vera Lanska, Vladimir Stanek, Jolana Mrazkova, Marie Gebauerova, Jiri Kettner, Josef Kautzner, Jan Pitha
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 12, Iss 8, Pp n/a-n/a (2024)
Abstract Background The highest mortality and morbidity worldwide is associated with atherosclerotic cardiovascular disease (ASCVD), which has in background both environmental and genetic risk factors. Apolipoprotein L1 (APOL1) variability influences
Externí odkaz:
https://doaj.org/article/c86151691d714cd7a63d5159a8791975
Autor:
Petr Kacer, Vera Adamkova, Jaroslav Alois Hubacek, Tereza Cervinkova, Vaclav Adamek, Ivana Kralova Lesna, Vera Lanska, Jan Pirk
Publikováno v:
Biomedical Papers, Vol 165, Iss 4, Pp 408-415 (2021)
Background. Post-infarction left ventricular free wall rupture (LVFWR) is a feared and catastrophic complication of myocardial infarction that carries a high surgical and hospital mortality. Due to the rarity of this complication, little information
Externí odkaz:
https://doaj.org/article/029727c02a2d466b812a3ea6167180be
Autor:
Jan Papez, Jiri Starha, Katerina Slaba, Jaroslav A Hubacek, Jakub Pecl, Stefania Aulicka, Milan Urik, Serdar Ceylaner, Petra Vesela, Ondrej Slaby, Petr Jabandziev
Publikováno v:
Biomedical Papers, Vol 165, Iss 4, Pp 454-457 (2021)
Background. Primary hypomagnesemia with secondary hypocalcemia (HSH) is a rare genetic disorder. Dysfunctional transient receptor potential melastatin 6 causes impaired intestinal absorption of magnesium, leading to low serum levels accompanied by hy
Externí odkaz:
https://doaj.org/article/41128d7da2d14bd8b8c01741231cabd0
Autor:
Jaroslav A. Hubacek, Ivana Kurcova, Vera Maresova, Alexandra Pankova, Lenka Stepankova, Kamila Zvolska, Vera Lanska, Eva Kralikova
Publikováno v:
Biomedical Papers, Vol 165, Iss 1, Pp 84-89 (2021)
Aim. Plasma values of nicotine and its metabolites are highly variable, and this variability has a strong genetic influence. In our study, we analysed the impact of common polymorphisms associated with smoking on the plasma values of nicotine, nicoti
Externí odkaz:
https://doaj.org/article/fb3ae92cae5749f4a284de47ce651529
Autor:
Libor Vitek, Jaroslav A. Hubacek, Andrzej Pajak, Agnieszka Doryńska, Magdalena Kozela, Lenka Eremiasova, Vilem Danzig, Denes Stefler, Martin Bobak
Publikováno v:
Annals of Hepatology, Vol 18, Iss 2, Pp 379-385 (2019)
Introduction and aim: It has been proposed that plasma concentration of bilirubin, an endogenous antioxidant, is protective against diseases mediated by increased oxidative stress, including cardiovascular diseases (CVD) and cancer. To examine this h
Externí odkaz:
https://doaj.org/article/6dfe490598f84e5cb218cf1fc9c84933
Autor:
Jaroslav A Hubacek, Yuri Nikitin, Yulia Ragino, Ekaterina Stakhneva, Hynek Pikhart, Anne Peasey, Michael V Holmes, Denes Stefler, Andrey Ryabikov, Eugeny Verevkin, Martin Bobak, Sofia Malyutina
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0260229 (2021)
This study investigated 12-year blood lipid trajectories and whether these trajectories are modified by smoking and lipid lowering treatment in older Russians. To do so, we analysed data on 9,218 Russian West-Siberian Caucasians aged 45-69 years at b
Externí odkaz:
https://doaj.org/article/f6be67ee0ace4a999ff61dc98c229f73
Autor:
Michal Vrablik, Lukas Tichý, Tomas Freiberger, Vladimir Blaha, Martin Satny, Jaroslav A. Hubacek
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Familial hypercholesterolemia (FH) is one of the most common monogenic diseases, leading to an increased risk of premature atherosclerosis and its cardiovascular complications due to its effect on plasma cholesterol levels. Variants of three genes (L
Externí odkaz:
https://doaj.org/article/c2464265792c48d195c020c78ae912e7
Autor:
Martin Jouza, Tomas Jimramovsky, Eva Sloukova, Jakub Pecl, Anna Seehofnerova, Marta Jezova, Milan Urik, Lumir Kunovsky, Katerina Slaba, Petr Stourac, Martina Klincova, Jaroslav A. Hubacek, Petr Jabandziev
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Respiratory distress syndrome caused by a secondary surfactant deficiency is one of the most common diagnoses requiring admission to the Neonatal Intensive Care Unit. We illustrate the case of a term female newborn without prenatal and peripartal ris
Externí odkaz:
https://doaj.org/article/6c925dd03e2b42f4bec7b9205492f1e2
Autor:
Adil Supiyev, Talgat Nurgozhin, Zhaxybay Zhumadilov, Anne Peasey, Jaroslav A. Hubacek, Martin Bobak
Publikováno v:
BMC Public Health, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background Despite high cardiovascular mortality in Central Asian republics of the former Soviet Union, there is limited information about major risk factors, including blood lipids. We investigated the prevalence of impaired concentrations
Externí odkaz:
https://doaj.org/article/7a5cd09d170349c68a7e3f890cdd4f95