Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Jaroslav ŠPonar"'
Publikováno v:
Journal of Molecular Structure. :585-589
A leucine zipper (bZIP) binding peptide BP1 was constructed based on the DNA binding sequence of the GCN4 protein, slightly modified to make it more similar to the sequence of other bZIP proteins (Jun) with related DNA binding specificity. Selfcomple
Publikováno v:
ResearcherID
A leucine zipper (bZip) binding peptide BP1 was constructed based on the DNA binding sequence of the GCN4 protein, slightly modified to make it more similar to the sequence of other bZip proteins (Jun) with related DNA binding specificity. Self-compl
Publikováno v:
Gene. 156:277-281
The 5′-end of the duck βA-globin promoter contains a protein binding site BS-3/Spl, the A + T-rich part of which could be involved in DNA bending. Plasmids were constructed using the pBend2 plasmid containing BS-3/Spl. Circular permutation analysi
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 11:869-880
The empirical potential including the intra- and intermolecular energy terms was used to study the interaction of L-Lysine-L-Alanine-L-Alanine Tripeptide with four models of B-DNA with different compositions. On the basis of a detailed search of the
Autor:
Jaroslav Šponar, Hana Votavová
Publikováno v:
International Journal of Biological Macromolecules. 15:139-144
The effect of basic oligopeptides (Lys-Ala-Ala)n and (Lys-Leu-Ala)n (n = 1-4) on the B-Z transition of poly(dG-m5dC).poly(dG-m5dC) in aqueous solution and in methanol-water mixtures was investigated by c.d. spectroscopy. In aqueous solution dimers an
Publikováno v:
Biopolymers. 31:275-283
The effect of basic oligopeptides (Lys-Ala-Ala)n (n = 1-5, 10) and (Lys-Leu-Ala)n (n = 1-4) on the B-Z transition of poly(dG-dC).poly(dG-dC) in water-methanol solutions was investigated using CD and uv spectroscopy. In the absence of peptides, the co
Publikováno v:
Journal of Computational Chemistry. 12:9-16
Interaction of a rigid fragment of B-DNA (polyanionic as well as screened by Na+ cations) with the flexible tripeptide Lys-Ala-Ala (in both L and D configurations) were investigated with the aid of an empirical potential. The potential consists of in
Autor:
Jaroslav Šponar, Jaromir Vlach
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 7:1083-1093
We have analysed by various approaches the structure of cloned synthetic sequences in supercoiled plasmids. Individual inserts were formed by d(C-G)n blocks interrupted by the presence of A.T pairs positioned either in phase or out of phase of pur-py
Autor:
Hana Votavová, Jaroslav Šponar
Publikováno v:
Journal of biomolecular structuredynamics. 13(6)
Repetitive basic polypeptides containing lysine or arginine as every third amino acid were shown to cause DNA condensation at physiological salt concentration connected with selective DNA binding with respect to DNA composition and sequence. This sel
Publikováno v:
Journal of biomolecular structuredynamics. 12(1)
Ten oligonucleotides of the length 8-12 base pairs have been synthesized, which contain, in addition to the obligatory sequences CG/CG, sequences not favorable for the transition to the Z conformation (A.T pairs, GG/CC or AA/TT sequences). Conformati