Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Jaroslav, Zajicek"'
Autor:
Shaun W. Lee, Teresa Brito-Robionson, Cunjia Qiu, Zhong Liang, Victoria A. Ploplis, Rashna D. Balsara, Jaroslav Zajicek, Yue Yuan, Francis J. Castellino
Publikováno v:
Journal of Structural Biology. 204:151-164
Group A Streptococcus pyogenes (GAS) is a causative agent of pharyngeal and dermal infections in humans. A major virulence determinant of GAS is its dimeric signature fibrillar M-protein (M-Prt), which is evolutionarily designed in modules, ranging f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f7b77d85b76090e898a563ade17735
https://doi.org/10.1016/j.jsb.2018.07.017
https://doi.org/10.1016/j.jsb.2018.07.017
Autor:
Victoria A. Ploplis, Yue Yuan, Cunjia Qiu, Francis J. Castellino, Shaun W. Lee, Vishwanatha Chandrahas, Jaroslav Zajicek
Publikováno v:
Journal of Biological Chemistry. 292:15016-15027
The binding of human plasminogen (hPg) to the surface of the human pathogen group A Streptococcus pyogenes (GAS) and subsequent hPg activation to the protease plasmin generate a proteolytic surface that GAS employs to circumvent host innate immunity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4250671c21e6d20e226ffb65347f03f5
https://doi.org/10.1074/jbc.m117.794198
https://doi.org/10.1074/jbc.m117.794198
Publikováno v:
Chemical Communications. 53:12774-12777
The repeating isoprene unit is a fundamental biosynthetic motif. The repetitive structure presents challenges both for synthesis and for structural characterization. In this synthesis of the (Z8,E2,ω)-undecaprenol of prokaryotic glycobiology, we exe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b7335907085e34741510f56b48358eb
https://doi.org/10.1039/c7cc06781j
https://doi.org/10.1039/c7cc06781j
Publikováno v:
Organic letters. 20(7)
A [1]rotaxane with two threaded α-cyclodextrin (α-CD) wheels was synthesized in 92% yield using a one-pot process at room temperature that employed spontaneous α-CD threading onto a twelve-carbon alkyl chain in water, followed by an oxime condensa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b04bb82b06978a662eb2d64232fdc1d
https://pubmed.ncbi.nlm.nih.gov/29542930
https://pubmed.ncbi.nlm.nih.gov/29542930
Autor:
Patrice Courvalin, Thierry Lambert, Jennifer Fishovitz, Marc Galimand, Jaroslav Zajicek, Shahriar Mobashery, Valérie Barbe
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:5647-5653
Corynebacterium striatum BM4687 was resistant to gentamicin and tobramycin but susceptible to kanamycin A and amikacin, a phenotype distinct among Gram-positive bacteria. Analysis of the entire genome of this strain did not detect any genes for known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2d8886fd6c140195452dd476e2f986
https://doi.org/10.1128/aac.01203-15
https://doi.org/10.1128/aac.01203-15
Publikováno v:
Journal of Biological Chemistry. 290:18156-18172
Conantokins are ~20-amino acid peptides present in predatory marine snail venoms that function as allosteric antagonists of ion channels of the N-methyl-d-aspartate receptor (NMDAR). These peptides possess a high percentage of post-/co-translationall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482437aceccd43eef47fd12dcd020168
https://doi.org/10.1074/jbc.m115.650341
https://doi.org/10.1074/jbc.m115.650341
Publikováno v:
The Journal of Organic Chemistry. 80:1795-1801
We report an efficient synthesis of 4H-benzo[b][1,4]thiazine 1,1-dioxides via unprecedented ring contraction of 2,5-dihydrobenzo[f][1,2,5]thiadiazepine 1,1-dioxides under mild conditions involving carbon-sulfur bond formation. 2,5-Dihydrobenzo[f][1,2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1deaffb16b8491915971d1ef31ee66
https://doi.org/10.1021/jo502713k
https://doi.org/10.1021/jo502713k
Autor:
Yue, Yuan, Jaroslav, Zajicek, Cunjia, Qiu, Vishwanatha, Chandrahas, Shaun W, Lee, Victoria A, Ploplis, Francis J, Castellino
Publikováno v:
The Journal of biological chemistry. 292(36)
The binding of human plasminogen (hPg) to the surface of the human pathogen group A Streptococcus pyogenes (GAS) and subsequent hPg activation to the protease plasmin generate a proteolytic surface that GAS employs to circumvent host innate immunity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b5ee43dea810c9f764f02e817ae0a46
https://pubmed.ncbi.nlm.nih.gov/28724633
https://pubmed.ncbi.nlm.nih.gov/28724633
Autor:
Mark A. Suckow, Ute Möllmann, Manuka Ghosh, William D. Claypool, Li Shuang, Weiqiang Huang, Valerie A. Schroeder, Jaroslav Zajicek, William R. Wolter, Honglin Yu, Marvin J. Miller, Patricia A. Miller
Publikováno v:
Journal of medicinal chemistry. 60(11)
In order to address the dire need for new antibiotics to treat specific strains of drug resistant Gram-negative bacterial infections, a mixed ligand analog of the natural Acinetobacter baumannii selective siderophore, fimsbactin, was coupled to dapto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e0180e8ac56f0a45037edd2b9f8a4c
https://pubmed.ncbi.nlm.nih.gov/28287735
https://pubmed.ncbi.nlm.nih.gov/28287735
Autor:
Jaroslav Zajicek, Michael L. Kostochka, Joseph A. Fuselier, Marcus A. Etienne, David H. Coy, Lichun Sun
Publikováno v:
Journal of Heterocyclic Chemistry. 52:1723-1730
Magnetic Resonance Research Center, Department of Chemistry and Biochemistry, University of Notre Dame,Notre Dame 46556, Indiana, USA*E-mail: mkostochka@yahoo.comAdditional Supporting Information may be found in the online version of this article.Rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51ebd9526795f7f5e69580832a9957da
https://doi.org/10.1002/jhet.2263
https://doi.org/10.1002/jhet.2263