Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Jaroslav, Chládek"'
Autor:
Renata Černá Pařízková, Jiřina Martínková, Eduard Havel, Petr Šafránek, Milan Kaška, David Astapenko, Jan Bezouška, Jaroslav Chládek, Vladimír Černý
Publikováno v:
Critical Care, Vol 25, Iss 1, Pp 1-9 (2021)
Abstract Background Meropenem dosing for septic critically patients is difficult due to pathophysiological changes associated with sepsis as well as supportive symptomatic therapies. A prospective single-center study assessed whether fluid retention
Externí odkaz:
https://doaj.org/article/a76aa8feec604a168cc8ab090189481a
Autor:
Hana Bavlovič Piskáčková, Hana Jansová, Jan Kubeš, Galina Karabanovich, Nela Váňová, Petra Kollárová-Brázdová, Iuliia Melnikova, Anna Jirkovská, Olga Lenčová-Popelová, Jaroslav Chládek, Jaroslav Roh, Tomáš Šimůnek, Martin Štěrba, Petra Štěrbová-Kovaříková
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The bisdioxopiperazine topoisomerase IIβ inhibitor ICRF-193 has been previously identified as a more potent analog of dexrazoxane (ICRF-187), a drug used in clinical practice against anthracycline cardiotoxicity. However, the poor aqueous s
Externí odkaz:
https://doaj.org/article/5b4e58f79de6467488f64f6509b130b3
Autor:
Eva Peterová, Jaroslav Chládek, Darina Kohoutová, Veronika Knoblochová, Paula Morávková, Jaroslava Vávrová, Martina Řezáčová, Jan Bureš
Publikováno v:
Acta Medica, Vol 61, Iss 1, Pp 8-16 (2018)
Analysis of Exhaled breath condensate (EBC) is a re-discovered approach to monitoring the course of the disease and reduce invasive methods of patient investigation. However, the major disadvantage and shortcoming of the EBC is lack of reliable and r
Externí odkaz:
https://doaj.org/article/9e6ac8af9f36478c8f6341ae906b55b0
Autor:
Martin Voborník, Marek Pojar, Jana Malakova, Šárka Studená, Věra Radochová, Mikita Karalko, Zdeněk Turek, Jaroslav Chládek, Jan Gofus, Jiří Manďák, Martin Děrgel
Publikováno v:
Surgical Infections. 22:283-291
Background: Single-lung ventilation facilitates surgical exposure during minimally invasive cardiac surgery. However, a deeper knowledge of antibiotic distribution within a collapsed lung is necessary for effective antibiotic prophylaxis of pneumonia
Autor:
Norbert Cibiček, Stanislav Mičuda, Jaroslav Chládek, Pavel Živný, Zdeněk Zadák, Eva Čermáková, Vladimír Palička
Publikováno v:
Acta Medica, Vol 49, Iss 4, Pp 227-231 (2006)
During shock, exposure of gut to ischemia determines patient’s survival. Ischemic preconditioning (ISP) elevates nitric oxide and blood perfusion, whereby it protects organs against subsequent severe ischemia/reperfusion. Using appropriate flow mar
Externí odkaz:
https://doaj.org/article/b6a1ec5d29864b05b0b96a9392dac474
In this paper we discuss the utilization of Variational Quantum Solver (VQE) and recently introduced Generalized Unitary Coupled Cluster (GUCC) formalism for the diagonalization of downfolded/effective Hamiltonians in active spaces. In addition to ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980aa06eaee8e16178188f001c2192a7
Autor:
Jolana Cermanova, Eva Doleželová, Alena Prasnicka, Drahomira Springer, Šárka Studená, Stanislav Micuda, Jaroslav Chládek
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 45(1)
Renal elimination of amikacin and other aminoglycosides is slowed down in sepsis-induced acute kidney injury increasing the risk of adverse effects. Since neutrophil gelatinase-associated lipocalin (NGAL) and aminoglycosides share the mechanisms for
Autor:
Martínková J, Stanislav Filip, Jaroslav Chládek, Ondřej Kubeček, Jana Malakova, Jiří Špaček, Milan Bláha, Miroslav Hodek
Publikováno v:
Cancer chemotherapy and pharmacology. 85(2)
The present study evaluates the safety and efficacy of double-plasma filtration (PF) to remove the exceeding pegylated liposomal doxorubicin (PLD) in circulation, thus reducing mucocutaneous toxicity. A total of 16 patients with platinum-resistant ov
Publikováno v:
Acta Medica, Vol 49, Iss 4, Pp 245-246 (2006)
Externí odkaz:
https://doaj.org/article/66e3deade9aa43c0bd5af5a220a0d031
Autor:
Pavel Tomsik, Milos Hroch, Stanislav Micuda, I Kloeting, Eva Dolezelova, Jolana Cermanova, Alena Prasnicka, Jaroslav Chládek, Lucie Rozkydalova
Publikováno v:
ResearcherID
Scopus-Elsevier
Europe PubMed Central
Scopus-Elsevier
Europe PubMed Central
The aim of the present study was to describe the currently poorly understood pharmacokinetics (PK) of boldine in control rats (LW, Lewis rats), and Mrp2 transporter-deficient rats (TR(-)). Animals from the LW and TR(-) groups underwent a bolus dose s