Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jaroslav, Bačovský"'
Publikováno v:
Interní medicína pro praxi. 20:44-48
Monoklonalni gamapatie (MG) jsou vysoce heterogenni skupinou zhoubných, větsinou ale nezhoubných stavů, jejichž spolecným jmenovatelem je přitomnost monoklonalniho imunoglobulinu (MIg, „paraproteinu“) nebo jeho strukturalnich komponent v s
Publikováno v:
Interní medicína pro praxi. 19:274-278
Monoklonalni gamapatie (MG) jsou vysoce heterogenni skupinou zhoubných i nezhoubných stavů, jejichž spolecným jmenovatelem je přitomnost monoklonalniho imunoglobulinu (MIg, „paraproteinu”) nebo jeho strukturalnich komponent v seru a/nebo v
Autor:
Jaroslav Bačovský, Vlastimil Scudla, Rudolf Metelka, Jiří Minařík, Jiří Vymětal, Tomas Pika, Pavel Lochman, Pavla Latalova, Jana Zapletalová
Publikováno v:
Klinicka onkologie. 26:343-347
BACKGROUND Symptomatic cardiac involvement is the most important prognostic factor in AL amyloidosis patients. Longterm survival is limited not only by cardiac involvement condition, but also by limited choice of treatment with unsatisfactory results
Autor:
Vlastimil, Ščudla, Pavel, Lochman, Tomáš, Pika, Jana, Zapletalová, Jiří, Minařík, Jaroslav, Bačovský
Publikováno v:
Casopis lekaru ceskych. 154(6)
The diagnostics and treatment of multiple myeloma (MM) requires precise analysis of serum immunoglobulins, which might be limited by the sensitivity of standard examination methods. Hevylite method enables quantitative analysis of heavy/light chain p
Autor:
Vlastimil Scudla, Jana Balcarkova, Marie Jarošová, Jaroslav Bačovský, Milena Holzerova, Karel Indrak, Helena Urbankova
Publikováno v:
Cancer Genetics and Cytogenetics. 192:68-72
Abnormalities of chromosome 1 are among the most frequent chromosomal aberrations in patients with multiple myeloma (MM) and are considered a poor-risk genetic feature. To define the frequency and minimal region of 1q gain, we performed immunophenoty
Autor:
Vlastimil, Ščudla, Pavla, Petrová, Tomáš, Pika, Pavel, Lochman, Jiří, Minařík, Jaroslav, Bačovský, Karel, Srovnalík
Publikováno v:
Casopis lekaru ceskych. 154(4)
Several recent studies aim at the detection of biological parameters that enable more precise diagnostics and stratification of monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM). The objective of our study was to ass
Autor:
Karel Indrak, Tomas Buchler, Zdeněk Adam, Adam Svobodník, Marta Krejčí, Vlastimil Scudla, Roman Hájek, Jaroslav Bačovský, Jiří Mayer, Andrea Křivanová, Jiří Vorlíček
Publikováno v:
Oncology Research and Treatment. 27:275-279
High-dose chemotherapy followed by autologous stem cell transplantation (AT) is accepted as first-line therapy for patients with multiple myeloma (MM), with very good tolerance and low mortality (2-3%).We tested repeated transplantation with differen
Autor:
Jiří, Minařík, Tomáš, Tichý, Tomáš, Pika, Jaroslav, Bačovský, Dagmar, Adamová, Karel, Srovnalík, Karel, Krejčí, Josef, Zadražil, Vlastimil, Sčudla
Publikováno v:
Vnitrni lekarstvi. 60(10)
Light chain deposition disease (LCDD) is a rare systemic condition caused by monoclonal proliferation of terminally differentiated B-lymphocytes with production of free light chains and their deposition in kidneys or other organs. The aim of our stud
Publikováno v:
Biomedical Papers. 146:59-61
The article deals with the clinical value of monitoring of serum markers of osteoresorption (ICTP) and bone formation (PICP) in multiple myeloma. In a group of patients treated by conventional chemotherapy and group of patients treated by high dose c
Publikováno v:
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia. 149(2)
In a group of 117 patients with multiple myeloma (MM) examined at the time of diagnosis, i.e. excluding previous chemotherapy, we analysed the levels of propidium-iodide (proliferative) - PC-PI/CD(138) and annexin-V (apoptotic) - PC-AI/CD(138) indice