Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Jarosław Walczak"'
Autor:
Karol Nienałtowski, Rachel E. Rigby, Jarosław Walczak, Karolina E. Zakrzewska, Edyta Głów, Jan Rehwinkel, Michał Komorowski
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Our ability to interpret single-cell multivariate signaling responses is still limited. Here the authors introduce fractional response analysis (FRA), involving fractional cell counting, capable of deconvoluting heterogeneous multivariate responses o
Externí odkaz:
https://doaj.org/article/51ea79c064944bc5ae1205ebb408cb88
Autor:
Jarosław Walczak, Dominika Malińska, Karolina Drabik, Bernadeta Michalska, Monika Prill, Stephanie Johne, Karsta Luettich, Jędrzej Szymański, Manuel C. Peitsch, Julia Hoeng, Jerzy Duszyński, Mariusz R. Więckowski, Marco van der Toorn, Joanna Szczepanowska
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 2, Pp 230-251 (2020)
Externí odkaz:
https://doaj.org/article/c60297642acf4fa0ba2006330c5a9ace
Autor:
Jarosław Walczak, Dariusz Ampuła
Publikováno v:
PROBLEMY TECHNIKI UZBROJENIA. 160:7-42
The article is dedicated to one of the most complex activities of the Republic of Poland in the field of security – state’s defence preparations. They are presented as all material, financial and organizational projects carried out by the public
Autor:
Piotr Topolewski, Karolina E. Zakrzewska, Jarosław Walczak, Karol Nienałtowski, Gerhard Müller-Newen, Abhyudai Singh, Michał Komorowski
Publikováno v:
Science signaling. 15(721)
Cellular signaling responses show substantial cell-to-cell heterogeneity, which is often ascribed to the inherent randomness of biochemical reactions, termed molecular noise, wherein high noise implies low signaling fidelity. Alternatively, heterogen
Autor:
Mariusz R. Wieckowski, Carole Mathis, Monika Prill, Jarosław Walczak, Karsta Luettich, Joanna Szczepanowska, Marco van der Toorn, Karolina Drabik, Jędrzej Szymański, Dominika Malinska, Paulina Patalas-Krawczyk, Manuel C. Peitsch, Jerzy Duszyński, Julia Hoeng, Bernadeta Michalska
Publikováno v:
Journal of Bioenergetics and Biomembranes
Mitochondria are multifunctional and dynamic organelles deeply integrated into cellular physiology and metabolism. Disturbances in mitochondrial function are involved in several disorders such as neurodegeneration, cardiovascular diseases, metabolic
Autor:
Stefanie Schreiber, Jarosław Walczak, Irina Miller, Werner Zuschratter, Joanna Szczepanowska, Wolfram S. Kunz, Susanne Petri, Grazyna Debska-Vielhaber, Viktoriya Peeva, Frank N. Gellerich, Judith Machts, Andreas Hermann, Stefan Vielhaber, Susanne Vogt
Publikováno v:
Experimental neurology 339, 113620-(2021). doi:10.1016/j.expneurol.2021.113620
Amyotrophic lateral sclerosis (ALS) is a devastating, rapidly progressive, neurodegenerative disorder affecting upper and lower motor neurons. Approximately 10% of patients suffer from familial ALS (FALS) with mutations in different ubiquitously expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ce0239394b8543c6e3988a83fae206
Autor:
Jarosław Walczak, Michał Komorowski, Rachel E. Rigby, Karol Nienałtowski, Jan Rehwinkel, Karolina Zakrzewska
Although we can now measure single-cell signaling responses with multivariate, high-throughput techniques our ability to interpret such measurements is still limited. Even interpretation of dose-response based on single-cell data is not straightforwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::619b79a7975624edfe228b29a0100686
https://doi.org/10.1101/2020.12.08.413468
https://doi.org/10.1101/2020.12.08.413468
Autor:
Rachel E. Rigby, Karol Nienałtowski, Edyta Głow, Jan Rehwinkel, Jarosław Walczak, Michał Komorowski, Karolina Zakrzewska
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Although we can now measure single-cell signaling responses with multivariate, high-throughput techniques our ability to interpret such measurements is still limited. Even interpretation of dose–response based on single-cell data is not straightfor
Autor:
Kamil Brygoła, Konstancja Kopyra, Urszula Karczmarczyk, Tomasz Ciach, Jolanta Duszak, Michał Szkop, Magdalena Janczewska, Anna Świątkowska, Michał Żuk, Grzegorz Pikus, Jarosław Walczak
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 167
Background Currently, radiotherapy is one of the most popular choices in clinical practice for the treatment of cancers. While it offers a fantastic means to selectively kill cancer cells, it can come with a host of side effects. To minimize such sid
Autor:
Małgorzata Partyka, Mariusz R. Wieckowski, Monika Prill, Alain Sewer, Karolina Drabik, Julia Hoeng, Bernadeta Michalska, Jędrzej Szymański, Paulina Patalas-Krawczyk, Marco van der Toorn, Stephanie Johne, Jarosław Walczak, Jerzy Duszyński, Joanna Szczepanowska, Aleksandra Wojtala, Dominika Malinska, Manuel C. Peitsch, Karsta Luettich
Publikováno v:
Food and Chemical Toxicology. 115:1-12
Mitochondrial dysfunction caused by cigarette smoke is involved in the oxidative stress-induced pathology of airway diseases. Reducing the levels of harmful and potentially harmful constituents by heating rather than combusting tobacco may reduce mit