Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Jarosław, Dudka"'
Publikováno v:
Cells, Vol 13, Iss 13, p 1151 (2024)
Doxorubicin (DOX) is an anthracycline anticancer agent that is highly effective in the treatment of solid tumors. Given the multiplicity of mechanisms involved in doxorubicin-induced cardiotoxicity, it is difficult to identify a precise molecular tar
Externí odkaz:
https://doaj.org/article/db88a6fca4f545ec84742d10fd08deeb
Autor:
Iwona Piątkowska-Chmiel, Monika Gawrońska-Grzywacz, Łukasz Popiołek, Mariola Herbet, Jarosław Dudka
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Diabetes is a chronic disease leading to memory difficulties and deterioration of learning abilities. The previous studies showed that modulation of inflammatory pathways in the diabetic brain may reduce dysfunction or cell death in brain ar
Externí odkaz:
https://doaj.org/article/002108bc21b049d19f485f2872bd15d5
Autor:
Paulina Kozakiewicz, Ludmiła Grzybowska-Szatkowska, Marzanna Ciesielka, Paulina Całka, Jacek Osuchowski, Paweł Szmygin, Bożena Jarosz, Marta Ostrowska-Leśko, Jarosław Dudka, Angelika Tkaczyk-Wlizło, Brygida Ślaska
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1183 (2023)
Mitochondria are organelles necessary for oxidative phosphorylation. The interest in the role of mitochondria in the process of carcinogenesis results from the fact that a respiratory deficit is found in dividing cells, especially in cells with accel
Externí odkaz:
https://doaj.org/article/6841a5ba27524d31a3a91eefb1930da0
2,4-Dinitrophenol as an Uncoupler Augments the Anthracyclines Toxicity against Prostate Cancer Cells
Publikováno v:
Molecules, Vol 27, Iss 21, p 7227 (2022)
One of the strategies for the treatment of advanced cancer diseases is targeting the energy metabolism of the cancer cells. The compound 2,4-DNP (2,4-dinitrophenol) disrupts the cell energy metabolism through the ability to decouple oxidative phospho
Externí odkaz:
https://doaj.org/article/44042cfbc5a640b7b92e5df59b9aba7c
Autor:
Monika Gawrońska-Grzywacz, Iwona Piątkowska-Chmiel, Łukasz Popiołek, Mariola Herbet, Jarosław Dudka
Publikováno v:
Pharmaceuticals, Vol 15, Iss 11, p 1308 (2022)
One of the most important therapies of malignant neoplasms, which are the second cause of death worldwide, is focused on the inhibition of pathological angiogenesis within the tumor. Therefore, the searching for the efficacious and relatively inexpen
Externí odkaz:
https://doaj.org/article/b2d9421e688a48d2b1b65696846cbf9e
Autor:
Agnieszka Korga, Marta Ostrowska, Magdalena Iwan, Małgorzata Skierucha, Aleksandra Józefczyk, Piotr Pawłowski, Jarosław Dudka, Ryszard Maciejewski, Robert Sitarz
Publikováno v:
Food & Nutrition Research, Vol 63, Iss 0, Pp 1-8 (2019)
Background: Gastric cancer (GC) remains one of the leading causes of cancer-related death. Its aetiology is multifactorial, but the major risk factor is a high in salt diet. During gastric carcinogenesis, cadherin-1 (CDH1) down-expression and cycloox
Externí odkaz:
https://doaj.org/article/f0695127f5764c47a3078d5c0d518244
Autor:
Mariola Herbet, Iwona Piątkowska-Chmiel, Monika Motylska, Monika Gawrońska-Grzywacz, Barbara Nieradko-Iwanicka, Jarosław Dudka
Publikováno v:
Brain Sciences, Vol 12, Iss 4, p 498 (2022)
Exposure to chronic stress leads to disturbances in glucose metabolism in the brain, and changes in the functioning of neurons coexisting with the development of depression. The detailed molecular mechanism and cerebral gluconeogenesis during depress
Externí odkaz:
https://doaj.org/article/42c547ac3c6a4cbb9d58da026dc7f9a7
Autor:
Iwona Piątkowska-Chmiel, Mariola Herbet, Monika Gawrońska-Grzywacz, Kamil Pawłowski, Marta Ostrowska-Leśko, Jarosław Dudka
Publikováno v:
Psychopharmacology. 240:983-1000
Diabetes causes a variety of molecular changes in the brain, making it a real risk factor for the development of cognitive dysfunction. Complex pathogenesis and clinical heterogeneity of cognitive impairment makes the efficacy of current drugs limite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c389f480cef5e37a9df31ce94254ad6f
https://doi.org/10.1007/s00213-023-06341-7
https://doi.org/10.1007/s00213-023-06341-7
Autor:
Mariola Herbet, Aleksandra Szopa, Anna Serefko, Sylwia Wośko, Monika Gawrońska-Grzywacz, Magdalena Izdebska, Iwona Piątkowska-Chmiel, Paulina Betiuk, Ewa Poleszak, Jarosław Dudka
Publikováno v:
Saudi Pharmaceutical Journal, Vol 26, Iss 5, Pp 694-702 (2018)
The objective of our study was to investigate whether 8-cyclopentyl-1,3-dimethylxanthine (CPT), associated with the adenosine system, enhances the antidepressant efficacy of antidepressant. All experiments were carried out on Albino Swiss mice. Follo
Externí odkaz:
https://doaj.org/article/80ece618d5eb4e93bfec90bc2eee9be2
Autor:
Grzegorz Adamczuk, Ewelina Humeniuk, Kamila Adamczuk, Barbara Madej-Czerwonka, Jarosław Dudka
Publikováno v:
Annals of Agricultural and Environmental Medicine. 30:65-76
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f033500a69e0162dde0ca9b096aacfb6
https://doi.org/10.26444/aaem/155382
https://doi.org/10.26444/aaem/155382