Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Jaromir Myslivecek"'
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S739- (2023)
Externí odkaz:
https://doaj.org/article/64adbdb507f74d23b85cede100a1ae30
Autor:
Jaromir Myslivecek, Chi-Wen Lung, Tania Martins-Marques, Samuel T. Orange, Mikio Hiura, Yonghe Ding
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/e495f7dbab0c4c4ca3afb3f23c57f551
Autor:
Jaromir Myslivecek
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Muscarinic receptors (mAChRs) are typical members of the G protein-coupled receptor (GPCR) family and exist in five subtypes from M1 to M5. Muscarinic receptor subtypes do not sufficiently differ in affinity to orthosteric antagonists or agonists; th
Externí odkaz:
https://doaj.org/article/379ef35b45fa4cb6b1ee7ca14c238883
Autor:
Jaromir Myslivecek
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Social species form organizations that support individuals because the consequent social behaviors help these organisms survive. The isolation of these individuals may be a stressor. We reviewed the potential mechanisms of the effects of social isola
Externí odkaz:
https://doaj.org/article/57e3cde087914f93ad036e324672d0f2
Autor:
Jaromir Myslivecek
Publikováno v:
Life, Vol 12, Iss 5, p 606 (2022)
The dopaminergic system is one of the most important neurotransmitter systems in the central nervous system (CNS). It acts mainly by activation of the D1-like receptor family at the target cell. Additionally, fine-tuning of the signal is achieved via
Externí odkaz:
https://doaj.org/article/d649495b347b40f3b85d135ffc2476e6
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Mice are nocturnal animals. Surprisingly, the majority of physiological/pharmacological studies are performed in the morning, i.e., in the non-active phase of their diurnal cycle. We have shown recently that female (not male) mice lacking the M4 musc
Externí odkaz:
https://doaj.org/article/c14be0b6d896421c97864d1fc954c36e
Autor:
Jaromir Myslivecek
Publikováno v:
Biomedicines, Vol 9, Iss 1, p 25 (2021)
Tight interactions exist between dopamine and acetylcholine signaling in the striatum. Dopaminergic neurons express muscarinic and nicotinic receptors, and cholinergic interneurons express dopamine receptors. All neurons in the striatum are pacemaker
Externí odkaz:
https://doaj.org/article/6aac4284e658468ea8834b8a28cfefae
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Autoradiography helps to determine the distribution and density of muscarinic receptor (MR) binding sites in the brain. However, it relies on the selectivity of radioligands toward their target. 3H-Pirenzepine is commonly believed to label predominan
Externí odkaz:
https://doaj.org/article/c47f81706b7e4fcc9a4a445041bca2c1
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68265 (2013)
Acetylcholinesterase (AChE) is a key enzyme in termination of fast cholinergic transmission. In brain, acetylcholine (ACh) is produced by cholinergic neurons and released in extracellular space where it is cleaved by AChE anchored by protein PRiMA. R
Externí odkaz:
https://doaj.org/article/12516a657e744683b0867fdeaeca8bd6
Publikováno v:
Physiol Res
The study examined the morphological and long-term behavioral impacts of neonatal hypoxic-ischemic brain injury in a mouse model. We investigated the modification of different behavioral domains, such as spontaneous climbing, which represents fine mo