Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Jarmo Wahlfors"'
Publikováno v:
BioTechniques, Vol 40, Iss 5, Pp 573-576 (2006)
Externí odkaz:
https://doaj.org/article/d37a346410bf4a639a5fbb93bcc7f703
Publikováno v:
BioTechniques, Vol 24, Iss 4, Pp 614-618 (1998)
Green fluorescent protein (GFP) and herpes simplex virus type-1 thymidine kinase (TK) are commonly used markers in gene transfer studies. The latter gene has also proven to be an effective tool in cancer “suicide” gene therapy. To facilitate rapi
Externí odkaz:
https://doaj.org/article/444831ecc5a34f08b1826ee0612a4599
Publikováno v:
International Journal of Molecular Medicine. 32:410-422
Sindbis vectors have shown remarkable antitumor efficacy and tumor-targeting capacity in animal models and hold promise for cancer therapy. Different packaging systems are used to produce propagation-incompetent Sindbis vectors. However, the vectors
Autor:
Ulla Nuutinen, Riikka Pellinen, Jonna Eeva, Antti Ropponen, Mine Eray, Jarmo Wahlfors, Jukka Pelkonen
Publikováno v:
Scandinavian Journal of Immunology. 70:565-573
Follicular lymphoma (FL) cells are malignant counterparts of germinal centre (GC) B cells. Microenvironment of FL B cells has an important role in the progression of FL and might also have an impact on the treatment of FL. CD40 is an important mediat
Autor:
Ulla Nuutinen, Jukka Pelkonen, Jarmo Wahlfors, Jonna Eeva, Antti Ropponen, Sanna Suoranta, Riikka Pellinen, Mine Eray
Publikováno v:
Leukemia Research. 33:1714-1717
Glucocorticoids are commonly used in the treatment of lymphoid malignancies. In this study, we show that apoptosis induced by dexamethasone (Dex), a synthetic glucocorticoid, was dependent on mitochondria, since overexpression of Bcl-X L prevented De
Autor:
Ulla Nuutinen, Jonna Eeva, Mikko Mättö, Riikka Pellinen, Antti Ropponen, Mine Eray, Jukka Pelkonen, Jarmo Wahlfors
Publikováno v:
Scandinavian Journal of Immunology. 70:574-583
During the germinal centre reaction (GC), B cells with non-functional or self-reactive antigen receptors are negatively selected by apoptosis to generate B cell repertoire with appropriate antigen specificities. We studied the molecular mechanism of
Autor:
Ari Hinkkanen, Ann-Marie Määttä, Riikka Pellinen, Anna Ketola, Marko Björn, Kimmo Mäkinen, Petra T. Furu, Timo Liimatainen, Tanja Hakkarainen, Jarmo Wahlfors, Risto Pirinen, Felicitas Yongabi
Publikováno v:
Cancer Research. 68:8342-8350
Oncolytic viruses are a promising tool for treatment of cancer. We studied an oncolytic Semliki Forest virus (SFV) vector, VA7, carrying the enhanced green fluorescent protein gene (EGFP), as a novel virotherapy candidate against unresectable osteosa
Autor:
Antti A. Aarnisalo, Jussi Jero, Laura Pietola, Riikka Pellinen, Jarmo Wahlfors, Joonas Joensuu
Publikováno v:
Acta Oto-Laryngologica. 128:613-620
GFP transgene was expressed in the lining cells of the perilymphatic space. Lentivirus vectors are safe and cause only minimal inflammatory reaction. Transgene products can be delivered into the perilymph by utilizing lentivirus vectors.To analyze th
Autor:
Ari Hinkkanen, Jarmo Wahlfors, Outi Rautsi, Markus Vähä-Koskela, Juhana M. Hakumäki, Thomas Wirth, Tiina Wahlfors, Ann-Marie Määttä, Katja Häkkinen, Linda C. Jansson, Piia Valonen, Kimmo Mäkinen, Riikka Pellinen, Timo Liimatainen
Publikováno v:
International Journal of Cancer. 121:863-870
Semliki Forest virus (SFV) is one of the latest candidates for a virotherapeutic agent against cancer, and recent studies have demonstrated its efficacy in tumor models. In the present study, we examined the antitumor efficacy of an avirulent SFV str
Publikováno v:
International Journal of Cancer. 118:2907-2910
We have earlier demonstrated that inhibition of polyamine biosynthesis with difluoromethylornithine (DFMO) can be used to enhance the cytotoxicity of herpes simplex virus thymidine kinase/ganciclovir (HSV-TK/GCV) gene therapy in different tumor cell