Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Jarmila Králová"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Information about cholesterol subcellular localization and transport pathways inside cells is essential for understanding and treatment of cholesterol-related diseases. However, there is a lack of reliable tools to monitor it. This work foll
Externí odkaz:
https://doaj.org/article/54d5150dd28a49a6a10522d69998985a
Autor:
Jarmila Králová, Michal Jurášek, Lucie Mikšátková, Anna Marešová, Jan Fähnrich, Petra Cihlářová, Pavel Drašar, Petr Bartůněk, Vladimír Král
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Fluorescent sterol probes, comprising a fluorophore connected to a sterol backbone by means of a linker, are promising tools for enabling high-resolution imaging of intracellular cholesterol. In this study, we evaluated how the size of the l
Externí odkaz:
https://doaj.org/article/9f4dc5143084469ea4450e9de614eba2
Heterocyclic sterol probes for live monitoring of sterol trafficking and lysosomal storage disorders
Autor:
Jarmila Králová, Michal Jurášek, Lucie Krčová, Bohumil Dolenský, Ivan Novotný, Michal Dušek, Zdeňka Rottnerová, Michal Kahle, Pavel Drašar, Petr Bartůněk, Vladimír Král
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract The monitoring of intracellular cholesterol homeostasis and trafficking is of great importance because their imbalance leads to many pathologies. Reliable tools for cholesterol detection are in demand. This study presents the design and synt
Externí odkaz:
https://doaj.org/article/0647f34dfb5f4375bc68e664338d2298
Autor:
Zdeněk Kejík, Robert Kaplánek, Petr Dytrych, Michal Masařík, Kateřina Veselá, Nikita Abramenko, David Hoskovec, Martina Vašáková, Jarmila Králová, Pavel Martásek, Milan Jakubek
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1879 (2021)
Designing optimal (neo)adjuvant therapy is a crucial aspect of the treatment of non-small-cell lung carcinoma (NSCLC). Standard methods of chemotherapy, radiotherapy, and immunotherapy represent effective strategies for treatment. However, in some ca
Externí odkaz:
https://doaj.org/article/a9212fe2fd9443cd854b6088bd96b44c
Autor:
Michal Dvořák, Roman Kodet, Zdena Zemanová, Dana Průková, Vít Karafiát, Jarmila Králová, Vladimír Pečenka, Petr Pajer
Supplementary Table 1 from Identification of Potential Human Oncogenes by Mapping the Common Viral Integration Sites in Avian Nephroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a926daa4099ee05cc93b3e23a5ffc9
https://doi.org/10.1158/0008-5472.22365129.v1
https://doi.org/10.1158/0008-5472.22365129.v1
Autor:
Michal Dvořák, Roman Kodet, Zdena Zemanová, Dana Průková, Vít Karafiát, Jarmila Králová, Vladimír Pečenka, Petr Pajer
Gene deregulation is a frequent cause of malignant transformation. Alteration of the gene structure and/or expression leading to cellular transformation and tumor growth can be experimentally achieved by insertion of the retroviral genome into the ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fbc6d0fe6b589b7ce103609b07e4df
https://doi.org/10.1158/0008-5472.c.6494547
https://doi.org/10.1158/0008-5472.c.6494547
Autor:
Jan Fähnrich, Lucie Mikšátková, Michal Jurášek, Vladimír Král, Petra Cihlářová, Petr Bartůněk, Pavel Drašar, Jarmila Králová, Anna Marešová
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Fluorescent sterol probes, comprising a fluorophore connected to a sterol backbone by means of a linker, are promising tools for enabling high-resolution imaging of intracellular cholesterol. In this study, we evaluated how the size of the linker, si
Early-onset pulmonary and cutaneous vasculitis driven by constitutively active SRC-family kinase HCK
Autor:
Jan Lebl, Eva Fronkova, Petr Novák, Tomas Brdicka, Marcela Dvorakova, Min Ae Lee-Kirsch, Jarmila Králová, Milan Macek, Ludmila Hornofova, Anna Sediva, Vendula Martinu, Jana Kayserova, Miroslav Koblizek, Michael Svaton, Petr Sedlacek, Ashleigh R Poh, Olga Zimmermannova, Ales Janda, Jana Paderova, Matthias Ernst, Tomas Kalina, Zuzana Parackova, Tamara Svobodová, Adam Klocperk, Stepanka Pruhova, Ondrej Hrusak, Veronika Kanderova, Simon Borna, Petr Pohunek, Martina Fejtkova
Background Inborn errors of immunity are genetic disorders characterized by various degrees of immune dysregulation that can manifest as immune deficiency, autoimmunity, or autoinflammation. The routine use of next-generation sequencing in the clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661be0062cb1ee5200e3673fa2a750d8
Autor:
Tomas Brdicka, Orest V. Matveichuk, Majd B. Protty, Vladimir Korinek, Jana Pokorná, Ales Drobek, Veronika Kanderova, Nataliia Pavliuchenko, Simon Borna, Matej Fabisik, Daniela Glatzová, Michael G. Tomlinson, Katarzyna Kwiatkowska, Iva Splichalova, Pavla Angelisova, Julia Starkova, Jarmila Králová, Petr Stanek, Meritxell Alberich-Jorda, Tereza Skopcova
Publikováno v:
Journal of Cellular and Molecular Medicine
WW domain binding protein 1‐like (WBP1L), also known as outcome predictor of acute leukaemia 1 (OPAL1), is a transmembrane adaptor protein, expression of which correlates with ETV6‐RUNX1 (t(12;21)(p13;q22)) translocation and favourable prognosis
Publikováno v:
Životné prostredie, Vol 53, Iss 4, Pp 199-203 (2019)
Mlyňany Arboretum is 127 years old and it has the largest woody-plant collection in Middle-Europe, with almost 2,000 taxa. Therefore, it is not surprising that this arboretum became a most important research institute focussing on foreign dendroflor