Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jarkko Toivonen"'
Autor:
Liang-Dar Hwang, Gabriel Cuellar-Partida, Loic Yengo, Jian Zeng, Jarkko Toivonen, Mikko Arvas, Robin N. Beaumont, Rachel M. Freathy, Gunn-Helen Moen, Nicole M. Warrington, David M. Evans
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Perinatal traits are influenced by fetal and maternal genomes. We investigate the performance of three strategies to detect loci in maternal and fetal genome-wide association studies (GWASs) of the same quantitative trait: (i) the traditiona
Externí odkaz:
https://doaj.org/article/6ec90594fb2a4675b78cffa420c5cf30
Autor:
Marieke Vinkenoog, Jarkko Toivonen, Tinus Brits, Dorien de Clippel, Veerle Compernolle, Surendra Karki, Marijke Welvaert, Amber Meulenbeld, Katja van den Hurk, Joost van Rosmalen, Emmanuel Lesaffre, Mikko Arvas, Mart Janssen
Publikováno v:
Vox Sanguinis. Wiley-Blackwell Publishing Ltd
VOX SANGUINIS
VOX SANGUINIS
Background and Objectives: Blood banks use a haemoglobin (Hb) threshold before blood donation to minimize donors' risk of anaemia. Hb prediction models may guide decisions on which donors to invite, and should ideally also be generally applicable, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f986a8eac77712f01b47ad9ef2a29a
https://doi.org/10.1111/vox.13426
https://doi.org/10.1111/vox.13426
Autor:
Femmeke J. Prinsze, Jarkko Toivonen, Markus Heinonen, Esa Turkulainen, Pietro Della Briotta Parolo, Yrjö Koski, Mikko Arvas
Publikováno v:
Vox Sanguinis. 117:504-512
Publisher Copyright: © 2021 The Authors. Vox Sanguinis published by John Wiley & Sons Ltd on behalf of International Society of Blood Transfusion. Background and Objectives: Deferral of blood donors due to low haemoglobin (Hb) is demotivating to don
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ae5e99345fbdf208926cadabdf522ea
https://doi.org/10.1111/vox.13223
https://doi.org/10.1111/vox.13223
Autor:
Kazuhiro R Nitta, Arttu Jolma, Yimeng Yin, Ekaterina Morgunova, Teemu Kivioja, Junaid Akhtar, Korneel Hens, Jarkko Toivonen, Bart Deplancke, Eileen E M Furlong, Jussi Taipale
Publikováno v:
eLife, Vol 4 (2015)
Divergent morphology of species has largely been ascribed to genetic differences in the tissue-specific expression of proteins, which could be achieved by divergence in cis-regulatory elements or by altering the binding specificity of transcription f
Externí odkaz:
https://doaj.org/article/11fa20f60f5d445aa2130f64f79fb476
Publikováno v:
Bioinformatics
Motivation Position-specific probability matrices (PPMs, also called position-specific weight matrices) have been the dominating model for transcription factor (TF)-binding motifs in DNA. There is, however, increasing recent evidence of better perfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa5c60b115791df20ecab64d67f3986
https://pubmed.ncbi.nlm.nih.gov/31999322
https://pubmed.ncbi.nlm.nih.gov/31999322
Autor:
Travis Gagie, Sophie Sverdlov, Dominik Kempa, Esko Ukkonen, Jarkko Toivonen, Leena Salmela, Alexandre P. Francisco
Publikováno v:
bioRxiv
Position weight matrices (PWMs) are the standard way to model binding site affinities in bioinformatics. However, they assume that symbol occurrences are position independent and, hence, they do not take into account symbols co-occurrence at differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f707fa1f9e60f40c52109b81b1e4a629
https://doi.org/10.1101/143024
https://doi.org/10.1101/143024
Autor:
Jarkko Toivonen, Jussi Taipale, Arttu Jolma, Jian Yan, Nicholas M. Luscombe, Mikko Taipale, Ekaterina Morgunova, Kimmo Palin, Kazuhiro R. Nitta, Tom Whitington, Patrick Lemaire, Martin Enge, Timothy P. Hughes, Esko Ukkonen, Teemu Kivioja, Gong-Hong Wei, Pasi Rastas, Renaud Vincentelli, Juan M. Vaquerizas
Publikováno v:
Cell. 152(1-2):327-339
SummaryAlthough the proteins that read the gene regulatory code, transcription factors (TFs), have been largely identified, it is not well known which sequences TFs can recognize. We have analyzed the sequence-specific binding of human TFs using high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9820ef8889f379d9f623e43f3f37fcd6
Autor:
Jussi Taipale, Arttu Jolma, Lu Cheng, Jian Yan, Esko Ukkonen, Mikko Taipale, Shaheynoor Talukder, Juan M. Vaquerizas, Gong-Hong Wei, Kimmo Palin, Martin Bonke, Martin Enge, Nicholas M. Luscombe, Jarkko Toivonen, Teemu Kivioja, Timothy P. Hughes, Mikko J. Sillanpää
Publikováno v:
Genome Research
The genetic code—the binding specificity of all transfer-RNAs—defines how protein primary structure is determined by DNA sequence. DNA also dictates when and where proteins are expressed, and this information is encoded in a pattern of specific s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3e1ddb0fa052bab5503b4483832ac5
https://doi.org/10.1101/gr.100552.109
https://doi.org/10.1101/gr.100552.109
Publikováno v:
Nucleic Acids Research
In some dimeric cases of transcription factor (TF) binding, the specificity of dimeric motifs has been observed to differ notably from what would be expected were the two factors to bind to DNA independently of each other. Current motif discovery met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9737d0d00f0d2f4641835ad841eb625a
https://doi.org/10.1093/nar/gky027
https://doi.org/10.1093/nar/gky027
Autor:
Jarkko Toivonen, Jussi Taipale, Teemu Kivioja, Arttu Jolma, Junaid Akhtar, Kazuhiro R. Nitta, Eileen E. M. Furlong, Ekaterina Morgunova, Korneel Hens, Yimeng Yin, Bart Deplancke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc94e7fe276d8dd0585475da2eb75d46
https://doi.org/10.7554/elife.04837.037
https://doi.org/10.7554/elife.04837.037