Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Jarkko Rautio"'
Autor:
Jelena Matović, Juulia Järvinen, Iris K. Sokka, Surachet Imlimthan, Olli Aitio, Mirkka Sarparanta, Jarkko Rautio, Filip S. Ekholm
Publikováno v:
Molecules, Vol 29, Iss 17, p 4263 (2024)
Boron Neutron Capture Therapy (BNCT) is a cancer treatment which combines tumor-selective boron delivery agents with thermal neutrons in order to selectively eradicate cancer cells. In this work, we focus on the early-stage development of carbohydrat
Externí odkaz:
https://doaj.org/article/9c47b19bd5b341ce9b2e8aff4ce2ab60
Autor:
Tatsiana Auchynnikava, Antti Äärelä, Heidi Liljenbäck, Juulia Järvinen, Putri Andriana, Luciana Kovacs, Jarkko Rautio, Johan Rajander, Pasi Virta, Anne Roivainen, Xiang-Guo Li, Anu J. Airaksinen
Publikováno v:
ACS Omega, Vol 8, Iss 48, Pp 45326-45336 (2023)
Externí odkaz:
https://doaj.org/article/3e6295ea4662448287917705d70fe616
Autor:
Elide Zingale, Angela Bonaccorso, Agata Grazia D’Amico, Rosamaria Lombardo, Velia D’Agata, Jarkko Rautio, Rosario Pignatello
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 125 (2024)
Recent studies have demonstrated that Sirtuin-1 (SIRT-1)-activating molecules exert a protective role in degenerative ocular diseases. However, these molecules hardly reach the back of the eye due to poor solubility in aqueous environments and low bi
Externí odkaz:
https://doaj.org/article/5232bc329c8944c1a3e7d48119c9ac9c
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2663 (2023)
Interest in the design of boronated amino acids has emerged, partly due to the utilization of boronophenylalanine (BPA), one of the two agents employed in clinical Boron Neutron Capture Therapy (BNCT). The boronated amino acids synthesized thus far f
Externí odkaz:
https://doaj.org/article/5e6a06840de845c5a2862ed77bfa6946
Autor:
Rosamaria Lombardo, Marika Ruponen, Jarkko Rautio, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Laura Calosi, Daniele Bani, Riikka Lampinen, Katja M. Kanninen, Anne M. Koivisto, Elina Penttilä, Heikki Löppönen, Rosario Pignatello
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1554 (2023)
Clozapine (CZP) is the only effective drug in schizophrenia resistant to typical antipsychotics. However, existing dosage forms (oral or orodispersible tablets, suspensions or intramuscular injection) show challenging limitations. After oral administ
Externí odkaz:
https://doaj.org/article/a9af83064787401fb31dedc14b1bfd1e
Publikováno v:
Journal of Functional Foods, Vol 31, Iss , Pp 237-247 (2017)
The bioactive compounds of Raphanus sativus var. caudatus Alef and their respective cytotoxicity were identified from (a) 2 crude water and dichloromethane extracts and (b) 5 serially partitioned extracts using dichloromethane. Then, using a bioassay
Externí odkaz:
https://doaj.org/article/51dce544708c451cbd4218a587e02f4a
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1230 (2020)
The treatment of various central nervous system (CNS) diseases has been challenging, despite the rapid development of several novel treatment approaches. The blood–brain barrier (BBB) is one of the major issues in the treatment of CNS diseases, hav
Externí odkaz:
https://doaj.org/article/4df689471cb740348f3f9c9b35e48b36
Autor:
Michael Gütschow, Jean Jacques Vanden Eynde, Josef Jampilek, CongBao Kang, Arduino A. Mangoni, Paola Fossa, Rafik Karaman, Andrea Trabocchi, Peter J. H. Scott, Jóhannes Reynisson, Simona Rapposelli, Stefania Galdiero, Jean-Yves Winum, Chiara Brullo, Katalin Prokai-Tatrai, Arun K. Sharma, Matthieu Schapira, Yasu-Taka Azuma, Laura Cerchia, Mariana Spetea, Giangiacomo Torri, Simona Collina, Athina Geronikaki, Alfonso T. García-Sosa, M. Helena Vasconcelos, Maria Emília Sousa, Ivan Kosalec, Tiziano Tuccinardi, Iola F. Duarte, Jorge A. R. Salvador, Massimo Bertinaria, Maurizio Pellecchia, Jussara Amato, Giulio Rastelli, Paula A. C. Gomes, Rita C. Guedes, Jean-Marc Sabatier, Ana Estévez-Braun, Bruno Pagano, Stefano Mangani, Rino Ragno, George Kokotos, Margherita Brindisi, Florenci V. González, Fernanda Borges, Mariarosaria Miloso, Jarkko Rautio, Diego Muñoz-Torrero
Publikováno v:
Molecules, Vol 25, Iss 13, p 2968 (2020)
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of editorials which is published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal Molecules [...]
Externí odkaz:
https://doaj.org/article/d1b45d5624194ce7bc35f0b2a26b0ee6
Autor:
Jean Jacques Vanden Eynde, Arduino A. Mangoni, Jarkko Rautio, Jérôme Leprince, Yasu-Taka Azuma, Alfonso T. García-Sosa, Christopher Hulme, Josef Jampilek, Rafik Karaman, Wei Li, Paula A. C. Gomes, Dimitra Hadjipavlou-Litina, Raffaele Capasso, Athina Geronikaki, Laura Cerchia, Jean-Marc Sabatier, Rino Ragno, Tiziano Tuccinardi, Andrea Trabocchi, Jean-Yves Winum, F. Javier Luque, Katalin Prokai-Tatrai, Mariana Spetea, Michael Gütschow, Ivan Kosalec, Catherine Guillou, M. Helena Vasconcelos, George Kokotos, Giulio Rastelli, Maria Emília de Sousa, Clementina Manera, Sandra Gemma, Stefano Mangani, Carlo Siciliano, Stefania Galdiero, Hong Liu, Peter J. H. Scott, Cristóbal de los Ríos, Luigi A. Agrofoglio, Simona Collina, Rita C. Guedes, Diego Muñoz-Torrero
Publikováno v:
Molecules, Vol 25, Iss 1, p 119 (2019)
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of Editorials that is published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal Molecules [...]
Externí odkaz:
https://doaj.org/article/3cd6ccb2d2144bde8974e0647ecc5397
Publikováno v:
Molecules, Vol 24, Iss 21, p 3869 (2019)
Sesamol is effective against melanoma cells with less damage to normal cells. The underlying selective cytotoxicity of sesamol in melanoma vs. non-cancerous cells is undefined. Melanoma cells differ from normal cells by over-expression of the L-type
Externí odkaz:
https://doaj.org/article/93fd7910a5504f8baedc913cdb3d84d0