Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jarkko, Valjakka"'
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26899- (2024)
Unnatural amino acids (UAAs) offer significant promise in a wide range of applications, including drug discovery, the custom design of peptides and proteins, and their utility and use as markers for monitoring molecular interactions in biological res
Externí odkaz:
https://doaj.org/article/0fbe17f5e92d431faea622abac15ab1d
Autor:
Jaakko Piesanen, Jarkko Valjakka, Sanna Niemelä, Marjut Borgenström, Seppo Nikkari, Vesa Hytönen, Juha Määttä, Tarja Kunnas
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0267343 (2022)
An association between genetic variants in the genes HFE, HJV, BMP4 and arterial hypertension has been shown earlier. Proteins encoded by these genes participate in the signalling routes leading eventually to the production of the peptide hormone hep
Externí odkaz:
https://doaj.org/article/a7c643d28ad148ddb2899867e6c29fde
Autor:
Huri Bulut, Jarkko Valjakka, Ossi Turunen, Berin Yilmazer, Ğarip Demir, Janne Jänis, Barış Binay
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
The Protein Journal. 39:519-530
NAD-dependent formate dehydrogenase (FDH) enzymes are frequently used in industrial and scientific applications. FDH is a reversible enzyme that reduces the NAD molecule to NADH and produces CO2 by oxidation of the formate ion, whereas it causes CO2
Autor:
Jouni Ruupunen, Mehmet Mervan Çakar, Barış Binay, Nicholas J. Turner, Jarkko Valjakka, Juan Mangas-Sanchez, Deniz Yildirim, William R. Birmingham, Ossi Turunen
Publikováno v:
Biotechnology Letters. 42:2251-2262
Formate dehydrogenases (FDHs) are NAD(P)H-dependent enzymes that catalyse the reversible oxidation of formate to CO2. The main goal was to use directed evolution to obtain variants of the FDH from Chaetomium thermophilum (CtFDH) with enhanced reducti
Autor:
Jaakko Piesanen, Jarkko Valjakka, Sanna Niemelä, Marjut Borgenström, Seppo Nikkari, Vesa Hytönen, Juha Määttä, Tarja Kunnas
Publikováno v:
PloS one. 17(4)
An association between genetic variants in the genes HFE, HJV, BMP4 and arterial hypertension has been shown earlier. Proteins encoded by these genes participate in the signalling routes leading eventually to the production of the peptide hormone hep
Publikováno v:
Critical reviews in biotechnology. 42(6)
In recent years, CO
In recent years, CO2 reduction and utilization have been proposed as an innovative solution for global warming and the ever-growing energy and raw material demands. In contrast to various classical methods, including chemical, electrochemical, and ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b732e377655dde0cea47c7402746d5
https://avesis.yyu.edu.tr/publication/details/bc3e1e2a-5a42-4103-86fb-43cba07ea7df/oai
https://avesis.yyu.edu.tr/publication/details/bc3e1e2a-5a42-4103-86fb-43cba07ea7df/oai
Autor:
Heini Kallio, Martti Tolvanen, Janne Jänis, Pei-wen Pan, Eeva Laurila, Anne Kallioniemi, Sami Kilpinen, Vilppu J Tuominen, Jorma Isola, Jarkko Valjakka, Silvia Pastorekova, Jaromir Pastorek, Seppo Parkkila
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27152 (2011)
Our previous microarray study showed that the non-specific cytotoxic cell receptor protein 1 (Nccrp1) transcript is significantly upregulated in the gastric mucosa of carbonic anhydrase IX (CA IX)-deficient (Car9(-/-)) mice. In this paper, we aimed t
Externí odkaz:
https://doaj.org/article/bae20915bfed4d848993aed335d49468
Autor:
Mehmet M, Çakar, Jouni, Ruupunen, Juan, Mangas-Sanchez, William R, Birmingham, Deniz, Yildirim, Ossi, Turunen, Nicholas J, Turner, Jarkko, Valjakka, Barış, Binay
Publikováno v:
Biotechnology letters. 42(11)
Formate dehydrogenases (FDHs) are NAD(P)H-dependent enzymes that catalyse the reversible oxidation of formate to COFour libraries were constructed targeting five residues in the active site. We identified two variants (G93H/I94Y and R259C) with enhan