Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Jarkko, Rautio"'
Autor:
Jelena Matović, Juulia Järvinen, Iris K. Sokka, Surachet Imlimthan, Olli Aitio, Mirkka Sarparanta, Jarkko Rautio, Filip S. Ekholm
Publikováno v:
Molecules, Vol 29, Iss 17, p 4263 (2024)
Boron Neutron Capture Therapy (BNCT) is a cancer treatment which combines tumor-selective boron delivery agents with thermal neutrons in order to selectively eradicate cancer cells. In this work, we focus on the early-stage development of carbohydrat
Externí odkaz:
https://doaj.org/article/9c47b19bd5b341ce9b2e8aff4ce2ab60
Autor:
Tatsiana Auchynnikava, Antti Äärelä, Heidi Liljenbäck, Juulia Järvinen, Putri Andriana, Luciana Kovacs, Jarkko Rautio, Johan Rajander, Pasi Virta, Anne Roivainen, Xiang-Guo Li, Anu J. Airaksinen
Publikováno v:
ACS Omega, Vol 8, Iss 48, Pp 45326-45336 (2023)
Externí odkaz:
https://doaj.org/article/3e6295ea4662448287917705d70fe616
Autor:
Elide Zingale, Angela Bonaccorso, Agata Grazia D’Amico, Rosamaria Lombardo, Velia D’Agata, Jarkko Rautio, Rosario Pignatello
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 125 (2024)
Recent studies have demonstrated that Sirtuin-1 (SIRT-1)-activating molecules exert a protective role in degenerative ocular diseases. However, these molecules hardly reach the back of the eye due to poor solubility in aqueous environments and low bi
Externí odkaz:
https://doaj.org/article/5232bc329c8944c1a3e7d48119c9ac9c
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2663 (2023)
Interest in the design of boronated amino acids has emerged, partly due to the utilization of boronophenylalanine (BPA), one of the two agents employed in clinical Boron Neutron Capture Therapy (BNCT). The boronated amino acids synthesized thus far f
Externí odkaz:
https://doaj.org/article/5e6a06840de845c5a2862ed77bfa6946
Autor:
Rosamaria Lombardo, Marika Ruponen, Jarkko Rautio, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Laura Calosi, Daniele Bani, Riikka Lampinen, Katja M. Kanninen, Anne M. Koivisto, Elina Penttilä, Heikki Löppönen, Rosario Pignatello
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1554 (2023)
Clozapine (CZP) is the only effective drug in schizophrenia resistant to typical antipsychotics. However, existing dosage forms (oral or orodispersible tablets, suspensions or intramuscular injection) show challenging limitations. After oral administ
Externí odkaz:
https://doaj.org/article/a9af83064787401fb31dedc14b1bfd1e
Autor:
Tarapong Srisongkram, Katayun Bahrami, Juulia Järvinen, Juri Timonen, Jarkko Rautio, Natthida Weerapreeyakul
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8446 (2022)
Sesamol is a compound reported to have anti-melanogenesis and anti-melanoma actions. Sesamol, however, has low intracellular drug concentration and fast excretion, which can limit its benefits in the clinic. To overcome this drawback and increase int
Externí odkaz:
https://doaj.org/article/5d486ff149a142d0837509d7012738af
Autor:
Katayun Bahrami, Juulia Järvinen, Tuomo Laitinen, Mika Reinisalo, Paavo Honkakoski, Antti Poso, Kristiina M. Huttunen, Jarkko Rautio
Publikováno v:
Molecular Pharmaceutics. 20:206-218
L-type amino acid transporter 1 (LAT1) transfers essential amino acids across cell membranes. Owing to its predominant expression in the blood-brain barrier and tumor cells, LAT1 has been exploited for drug delivery and targeting to the central nervo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3bc3c3e2892be8ef3d43334e6ffd537
https://doi.org/10.1021/acs.molpharmaceut.2c00594
https://doi.org/10.1021/acs.molpharmaceut.2c00594
Publikováno v:
Journal of Functional Foods, Vol 31, Iss , Pp 237-247 (2017)
The bioactive compounds of Raphanus sativus var. caudatus Alef and their respective cytotoxicity were identified from (a) 2 crude water and dichloromethane extracts and (b) 5 serially partitioned extracts using dichloromethane. Then, using a bioassay
Externí odkaz:
https://doaj.org/article/51dce544708c451cbd4218a587e02f4a
Autor:
Jelena Matović, Katayun Bahrami, Philipp Stockmann, Iris K. Sokka, You Cheng Khng, Mirkka Sarparanta, Evamarie Hey-Hawkins, Jarkko Rautio, Filip S. Ekholm
Publikováno v:
Molecular Pharmaceutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c1e4a225677d7dd5243d38b06858293
https://doi.org/10.1021/acs.molpharmaceut.3c00119
https://doi.org/10.1021/acs.molpharmaceut.3c00119
Autor:
Jann N. Sakaria, Richard T. Wheelhouse, Alonzo H. Ross, Jarkko Rautio, Mikko Gynther, Roger M. Phillips, Ann C. Mladek, Yulian P. Ramirez
Supplementary Figure S5. DNA damage signaling activated by low concentrations of DP68. U251 and T98G cells were exposed to DP68 for 24 hrs and whole cell and nuclear extracts were processed for Western blotting. Representative blots from three indepe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0434cb986f1d6fcbe341f24a6769684
https://doi.org/10.1158/1535-7163.22502478.v1
https://doi.org/10.1158/1535-7163.22502478.v1
