Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jari Pajander"'
Publikováno v:
Computer Aided Chemical Engineering ISBN: 9780323851596
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43e59e404e2ef61c725046e3c7b41f6f
https://doi.org/10.1016/b978-0-323-85159-6.50357-2
https://doi.org/10.1016/b978-0-323-85159-6.50357-2
Autor:
Lene Jorgensen, Jonatan Riis Christensen, Holger Grohganz, Helena Meng-Lund, Jari Pajander, Ossi Korhonen, Tuomo Laitinen, Antti Poso
Publikováno v:
European Journal of Pharmaceutical Sciences. 102:188-195
In recent years, the demand and interest for functionalized polymers have increased for drug delivery purposes. Because of the increased interest, methods that can be used to predict physical and chemical properties of polymers prior to synthesis wou
Publikováno v:
Journal of Drug Delivery Science and Technology. 34:1-9
In the present study, the stabilizing effect of excipients present in recombinant Human Serum Albumin (rHSA) solutions are studied using rheological analysis. The study was conducted using Design of Experiment (DoE) principles and multivariate analys
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 80:116-125
Despite the increased request for robust quality systems, the end product may contain unidentified defects or discoloured regions. The foreign matter has to be monitored, identified and its source defined in order to prevent further contamination. Ho
Publikováno v:
Journal of Pharmaceutical Sciences. 102:1385-1403
The manufacturing of tablets involves many unit operations that possess multivariate and complex characteristics. The interactions between the material characteristics and process related variation are presently not comprehensively analyzed due to un
Autor:
Stefania Baldursdottir, P. Barbre Pedersen, Jari Pajander, Louise von Gersdorff Jørgensen, Anette Müllertz, Peter Vilmann
Publikováno v:
Scopus-Elsevier
University of Copenhagen
University of Copenhagen
Macromolecular substances are included in most pharmaceutical dosage forms. Their physicochemical properties are important for the performance of the end product, and thus rheological behavior becomes a critical quality attribute. Rheology is a well-
Publikováno v:
International journal of pharmaceutics. 518(1-2)
The effect of product design parameters on the formation and properties of an injection molded solid dosage form consisting of poly(ethylene oxide)s (PEO) and two different active pharmaceutical ingredients (APIs) was studied. The product design para
Autor:
Jari Pajander, Risto A. Hakala, Jukka Seppälä, Pekka Savolainen, Juha Mönkäre, Maija Järveläinen, Harri Korhonen, Kristiina Järvinen
Publikováno v:
European Journal of Pharmaceutical Sciences. 47:170-178
Surface-eroding biodegradable polymers can provide many advantages in drug delivery, such as controllable and zero-order drug release. Photocrosslinkable poly(ester anhydride)s are a recently developed family of surface-eroding polymers with readily
Publikováno v:
International Journal of Pharmaceutics. 427:345-353
The aim of the study was to visualize the behaviour of the hydroxypropyl methylcellulose (HPMC) in a buffer solution using UV imaging. The obtained results were related to rheological measurements in order to gain insight into critical polymer proper
Influence of solvent evaporation rate and formulation factors on solid dispersion physical stability
Publikováno v:
European Journal of Pharmaceutical Sciences. 44:610-620
New chemical entities (NCEs) often show poor water solubility necessitating solid dispersion formulation. The aim of the current study is to employ design of experiments in investigating the influence of one critical process factor (solvent evaporati