Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jari P. Lappalainen"'
Autor:
Anna-Liisa Levonen, Seppo Ylä-Herttuala, Minna U. Kaikkonen, Hanna P. Lesch, Haritha Samaranayake, Jari P. Lappalainen, Jere T. Pikkarainen, Emilia Kansanen, Suvi M. Kuosmanen, Heidi M. Laitinen, Ann-Marie Määttä, Anna-Kaisa Ruotsalainen, Hanna M. Leinonen
Nuclear factor erythroid-2 related factor 2 (Nrf2) is a transcription factor that regulates protection against a wide variety of toxic insults to cells, including cytotoxic cancer chemotherapeutic drugs. Many lung cancer cells harbor a mutation in ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90bf3aae97f86781220c782bc7ad87cf
https://doi.org/10.1158/0008-5472.c.6503937.v1
https://doi.org/10.1158/0008-5472.c.6503937.v1
Autor:
Anna-Liisa Levonen, Seppo Ylä-Herttuala, Minna U. Kaikkonen, Hanna P. Lesch, Haritha Samaranayake, Jari P. Lappalainen, Jere T. Pikkarainen, Emilia Kansanen, Suvi M. Kuosmanen, Heidi M. Laitinen, Ann-Marie Määttä, Anna-Kaisa Ruotsalainen, Hanna M. Leinonen
PDF file - 57K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8be17f97492eeb4676915474595fc4
https://doi.org/10.1158/0008-5472.22394055.v1
https://doi.org/10.1158/0008-5472.22394055.v1
Autor:
Anna-Liisa Levonen, Seppo Ylä-Herttuala, Minna U. Kaikkonen, Hanna P. Lesch, Haritha Samaranayake, Jari P. Lappalainen, Jere T. Pikkarainen, Emilia Kansanen, Suvi M. Kuosmanen, Heidi M. Laitinen, Ann-Marie Määttä, Anna-Kaisa Ruotsalainen, Hanna M. Leinonen
PDF file - 324K, The effect of ganciclovir and doxorubicin on ARE activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551fa5c0ca79e2e61797c8aabe5105b3
https://doi.org/10.1158/0008-5472.22394058.v1
https://doi.org/10.1158/0008-5472.22394058.v1
Autor:
Johanna P. Laakkonen, Henri Niskanen, Lari Holappa, Jari P. Lappalainen, Seppo Ylä-Herttuala, H. H. Pulkkinen, Minna U. Kaikkonen, Mustafa Beter, M. Kiema, Annakaisa Tirronen, Anu Toropainen
Publikováno v:
Angiogenesis
The BMP/TGFβ-Smad, Notch and VEGF signaling guides formation of endothelial tip and stalk cells. However, the crosstalk of bone morphogenetic proteins (BMPs) and vascular endothelial growth factor receptor 2 (VEGFR2) signaling has remained largely u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977f91e013549ed6b56892cd19c3e8a5
http://europepmc.org/articles/PMC7921060
http://europepmc.org/articles/PMC7921060
Autor:
Line Lottonen-Raikaslehto, Mari Merentie, Emilia Kansanen, Kai Kaarniranta, Anna-Liisa Levonen, Emmi Heiskanen, Virve Sihvola, Matti Jauhiainen, Eija Pirinen, Juha Näpänkangas, Seppo Ylä-Herttuala, Anna-Kaisa Ruotsalainen, Jari P. Lappalainen, Simone Adinolfi
Aims Oxidative stress and inflammation play an important role in the progression of atherosclerosis. Transcription factor NF-E2-related factor 2 (Nrf2) has antioxidant and anti-inflammatory effects in the vessel wall, but paradoxically, global loss o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d540ded4e01c32fe7b4f860bb1da459c
http://hdl.handle.net/10138/311312
http://hdl.handle.net/10138/311312
Autor:
Jari P. Lappalainen, Erwin van Wijk, Ilse Roodink, Stef J.F. Letteboer, William P.J. Leenders, Seppo Ylä-Herttuala, Joost J.C. Verhoeff, Ronald Roepman, Kiek Verrijp, Petri I. Mäkinen, Jos M.H. Raats, Sanne A. M. van Lith
Publikováno v:
Oncotarget
Oncotarget, 7(44), 71594-71607. Impact Journals
Oncotarget, 7(44), 71594. Impact Journals
Oncotarget, 7(44), 71594-71607. Impact Journals
Oncotarget, 7(44), 71594. Impact Journals
// Sanne A.M. van Lith 1, * , Ilse Roodink 1, 5, * , Joost J.C. Verhoeff 2 , Petri I. Makinen 3 , Jari P. Lappalainen 3 , Seppo Yla-Herttuala 3, 4 , Jos Raats 5 , Erwin van Wijk 6 , Ronald Roepman 7 , Stef J. Letteboer 7 , Kiek Verrijp 1 , William P.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a14971197142f3c7407de9ecc0c6b98
https://doi.org/10.18632/oncotarget.12261
https://doi.org/10.18632/oncotarget.12261
Autor:
Thomas L. Theelen, Mat J.A.P. Daemen, Jari P. Lappalainen, Erik A.L. Biessen, Jack P.M. Cleutjens, Marion J.J. Gijbels, Judith C. Sluimer, Erika Gurzeler, Kari Alitalo, Seppo Ylä-Herttuala
Publikováno v:
Atherosclerosis
Atherosclerosis, 241(2), 297-304. Elsevier Ireland Ltd
Atherosclerosis, 241(2), 297-304. Elsevier Ireland Ltd
Objective Angiopoietin-2 (Ang-2) blocking agents are currently undergoing clinical trials for use in cancer treatment. Ang-2 has also been associated with rupture-prone atherosclerotic plaques in humans, suggesting a role for Ang-2 in plaque stabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44265dc3be51734e2ae52133e0ecec8f
https://doi.org/10.1016/j.atherosclerosis.2015.05.018
https://doi.org/10.1016/j.atherosclerosis.2015.05.018
Autor:
Anna-Kaisa Ruotsalainen, Heidi Laitinen, Masayuki Yamamoto, Tero Vatanen, Seppo Ylä-Herttuala, Petri I. Mäkinen, Sohvi Hörkkö, Matias Inkala, Matti Jauhiainen, Jari P. Lappalainen, Janne Heikkilä, Anna-Liisa Levonen, Mervi E. Partanen, Suvi E. Heinonen, Emilia Kansanen
Publikováno v:
Cardiovascular Research. 98:107-115
Aims The loss of nuclear factor E2-related factor 2 (Nrf2) has been shown to protect against atherogenesis in apoE-deficient mice. The mechanism by which Nrf2 deficiency affords atheroprotection in this model is currently unknown, but combined system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2519ffd4cc9b783348195accb171e30
https://doi.org/10.1093/cvr/cvt008
https://doi.org/10.1093/cvr/cvt008
Autor:
Thomas L. Theelen, Suvi Jauhiainen, Seppo Ylä-Herttuala, Pyry I. Toivanen, Johanna P. Laakkonen, Minna U. Kaikkonen, Judith C. Sluimer, Jari P. Lappalainen, Tiina Nieminen
Publikováno v:
Angiogenesis
Angiogenesis, 20(1), 109-124. Springer, Cham
Angiogenesis, 20(1), 109-124. Springer, Cham
Histamine and vascular endothelial growth factor A (VEGF) are central regulators in vascular pathologies. Their gene regulation leading to vascular remodeling has remained obscure. In this study, EC regulation mechanisms of histamine and VEGF were co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2330bad13a3345ca7fea858c0d1c0506
https://pubmed.ncbi.nlm.nih.gov/27873103
https://pubmed.ncbi.nlm.nih.gov/27873103
Autor:
Hanna P. Lesch, Emilia Kansanen, Ann-Marie Määttä, Anna-Liisa Levonen, Hanna Leinonen, Heidi Laitinen, Jari P. Lappalainen, Jere Pikkarainen, Seppo Ylä-Herttuala, Haritha Samaranayake, Anna-Kaisa Ruotsalainen, Minna U. Kaikkonen, Suvi M. Kuosmanen
Publikováno v:
Cancer Research. 72:6227-6235
Nuclear factor erythroid-2 related factor 2 (Nrf2) is a transcription factor that regulates protection against a wide variety of toxic insults to cells, including cytotoxic cancer chemotherapeutic drugs. Many lung cancer cells harbor a mutation in ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c66e19ef4854a7db865aa6c0fa652030
https://doi.org/10.1158/0008-5472.can-12-1166
https://doi.org/10.1158/0008-5472.can-12-1166