Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Jari Metso"'
Autor:
Priyanka Negi, Taina Heikkilä, Karoliina Vuorenpää, Emilia Tuunainen, Wail Nammas, Teemu Maaniitty, Juhani Knuuti, Jari Metso, Janita Lövgren, Matti Jauhiainen, Urpo Lamminmäki, Kim Pettersson, Antti Saraste
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectiveHigh-density lipoprotein (HDL) is a heterogeneous group of subpopulations differing in protein/lipid composition and in their anti-atherogenic function. There is a lack of assays that can target the functionality of HDL particles related to
Externí odkaz:
https://doaj.org/article/d8f5248c1ad345a0a3d4f9e782875e22
Autor:
Shahan Syed, Eija Nissilä, Hanna Ruhanen, Satoshi Fudo, Meztlli O. Gaytán, Sanna P. Sihvo, Martina B. Lorey, Jari Metso, Katariina Öörni, Samantha J. King, Oommen P. Oommen, Matti Jauhiainen, Seppo Meri, Reijo Käkelä, Karita Haapasalo
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102535- (2021)
Summary: High-density lipoproteins (HDLs) are a group of different subpopulations of sialylated particles that have an essential role in the reverse cholesterol transport (RCT) pathway. Importantly, changes in the protein and lipid composition of HDL
Externí odkaz:
https://doaj.org/article/3e4c3e38f17f49da9c2a20ebcdc46cc0
Autor:
Maija Ruuth, Jarkko Soronen, Essi Kaiharju, Krista Merikanto, Julia Perttilä, Jari Metso, Miriam Lee-Rueckert, Marja-Riitta Taskinen, Petri T. Kovanen, Katariina Öörni, Vesa M. Olkkonen, Matti S. Jauhiainen, Pirkka-Pekka Laurila
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-11 (2018)
Abstract Background The focus of studies on high-density lipoproteins (HDL) has shifted from HDL-cholesterol (HDL-C) to HDL function. We recently demonstrated that low USF1 expression in mice and humans associates with high plasma HDL-C and low trigl
Externí odkaz:
https://doaj.org/article/2cd6a50d4fb14b3aa27cb47c48a2f327
Autor:
Jaakko Leskelä, Milla Pietiäinen, Anton Safer, Markku Lehto, Jari Metso, Ernst Malle, Florian Buggle, Heiko Becher, Jouko Sundvall, Armin J Grau, Pirkko J Pussinen, Frederick Palm
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228806 (2020)
INTRODUCTION:Periodontitis is associated with increased serum lipopolysaccharide (LPS) activity, which may be one mechanism linking periodontitis with the risk of cardiovascular diseases. As LPS-carrying proteins including lipoproteins modify LPS-act
Externí odkaz:
https://doaj.org/article/c3600a26f8124e4781f73a6d73152037
Autor:
Ilenia Minicocci, Anna Tikka, Eleonora Poggiogalle, Jari Metso, Anna Montali, Fabrizio Ceci, Giancarlo Labbadia, Mario Fontana, Alessia Di Costanzo, Marianna Maranghi, Aldo Rosano, Christian Ehnholm, Lorenzo Maria Donini, Matti Jauhiainen, Marcello Arca
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 6, Pp 1097-1107 (2016)
The consequences of angiopoietin-like protein 3 (ANGPTL3) deficiency on postprandial lipid and lipoprotein metabolism has not been investigated in humans. We studied 7 homozygous (undetectable circulating ANGPTL3 levels) and 31 heterozygous (50% of c
Externí odkaz:
https://doaj.org/article/e3b959eb3eb143e98fb585b680745bdf
Autor:
Lídia Cedó, Sara Fernández-Castillejo, Laura Rubió, Jari Metso, David Santos, Daniel Muñoz-Aguayo, Andrea Rivas-Urbina, Mireia Tondo, Karen Alejandra Méndez-Lara, Marta Farràs, Matti Jauhiainen, Maria-José Motilva, Montserrat Fitó, Francisco Blanco-Vaca, Rosa Solà, Joan Carles Escolà-Gil
Publikováno v:
Biomedicines, Vol 8, Iss 8, p 266 (2020)
The intake of olive oil (OO) enriched with phenolic compounds (PCs) promotes ex vivo HDL-mediated macrophage cholesterol efflux in humans. We aimed to determine the effects of PC-enriched virgin OO on reverse cholesterol transport (RevCT) from macrop
Externí odkaz:
https://doaj.org/article/0a2620456b364026b366ae821bc16dd6
Autor:
Eija Nissilä, Pipsa Hakala, Katarzyna Leskinen, Angela Roig, Shahan Syed, Kok P. M. Van Kessel, Jari Metso, Carla J. C. De Haas, Päivi Saavalainen, Seppo Meri, Angeliki Chroni, Jos A. G. Van Strijp, Katariina Öörni, Matti Jauhiainen, T. Sakari Jokiranta, Karita Haapasalo
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The alternative pathway (AP) of complement is constantly active in plasma and can easily be activated on self surfaces and trigger local inflammation. Host cells are protected from AP attack by Factor H (FH), the main AP regulator in plasma. Although
Externí odkaz:
https://doaj.org/article/50fa5f1b73774b2ebc5f09103838760f
Autor:
Timo Paavola, Sanna Kuusisto, Matti Jauhiainen, Sakari Kakko, Tiia Kangas-Kontio, Jari Metso, Pasi Soininen, Mika Ala-Korpela, Risto Bloigu, Minna L Hannuksela, Markku J Savolainen, Tuire Salonurmi
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171993 (2017)
OBJECTIVE:The potential of high-density lipoproteins (HDL) to facilitate cholesterol removal from arterial foam cells is a key function of HDL. We studied whether cholesterol efflux to serum and HDL subfractions is impaired in subjects with early cor
Externí odkaz:
https://doaj.org/article/711dbca8ab734a5daf70a89a2d7e56f4
Autor:
Su Duy Nguyen, Katariina Öörni, Miriam Lee-Rueckert, Tero Pihlajamaa, Jari Metso, Matti Jauhiainen, Petri T. Kovanen
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 10, Pp 2115-2125 (2012)
HDL particles may enter atherosclerotic lesions having an acidic intimal fluid. Therefore, we investigated whether acidic pH would affect their structural and functional properties. For this purpose, HDL2 and HDL3 subfractions were incubated for vari
Externí odkaz:
https://doaj.org/article/42dedde61301410cb3b83c1f050bba55
Autor:
Niko L. Setälä, Juha M. Holopainen, Jari Metso, Gebrenegus Yohannes, Jaakko Hiidenhovi, Leif C. Andersson, Ove Eriksson, Alexandra Robciuc, Matti Jauhiainen
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 11, Pp 3126-3134 (2010)
In addition to circulation, where it transfers phospholipids between lipoprotein particles, phospholipid transfer protein (PLTP) was also identified as a component of normal tear fluid. The purpose of this study was to clarify the secretion route of
Externí odkaz:
https://doaj.org/article/5f78059cd14443ad8c079fb2087d4d9f