Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jari Jukkola"'
Autor:
Jari Jukkola, Mika Kaakinen, Abhishek Singh, Sadegh Moradi, Hany Ferdinando, Teemu Myllylä, Vesa Kiviniemi, Lauri Eklund
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-14 (2024)
Abstract Background Inside the incompressible cranium, the volume of cerebrospinal fluid is directly linked to blood volume: a change in either will induce a compensatory change in the other. Vasodilatory lowering of blood pressure has been shown to
Externí odkaz:
https://doaj.org/article/31041fce1f9a4364885b7a17f7bdff49
Autor:
Mahsima Khoshneviszadeh, Solveig Jandke, Lorena Morton, Rahul Kaushik, Philipp Arndt, Oula Norman, Jari Jukkola, Ildiko Rita Dunay, Constanze Seidenbecher, Anne Heikkinen, Stefanie Schreiber, Alexander Dityatev
Collagen XVIII (COL18A1) is an abundant heparan sulfate proteoglycan in vascular basement membranes. Here, we asked (i) if the loss of collagen XVIII would result in blood-brain barrier (BBB) breakdown, pathological alterations of small arteries and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be284a7998f890c4cabcb4ee197716ff
https://doi.org/10.21203/rs.3.rs-1980968/v2
https://doi.org/10.21203/rs.3.rs-1980968/v2
Autor:
Mahsima Khoshneviszadeh, Solveig Jandke, Rahul Kaushik, Philipp Ulbrich, Oula Norman, Jari Jukkola, Anne Heikkinen, Stefanie Schreiber, Alexander Dityatev
BackgroundThe pathological alterations of small arteries and capillaries defined as cerebral small vessel disease (CSVD) are characterized by age-dependent blood-brain barrier (BBB) breakdown and vessel wall remodeling manifesting in small vessel occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1c07049e3e4dc13ba615b6c59cbb533
https://doi.org/10.21203/rs.3.rs-1980968/v1
https://doi.org/10.21203/rs.3.rs-1980968/v1
Autor:
Hany Ferdinando, Lauri Eklund, Teemu Myllylä, Jari Jukkola, Vesa Korhonen, Erkki Vihriälä, Vesa Kiviniemi, Mika Kaakinen, Zuomin Zhao
Publikováno v:
Tissue Optics and Photonics.
Enhancing brain fluid movement across blood brain barrier (BBB) has been recognized as a potential treatment of neurodegenerative diseases. Moreover, BBB opening is of high interest also in brain drug delivery in the treatment of brain tumors/cancers
Autor:
Lauri Eklund, Vesa Korhonen, Aleksandra Zienkiewicz, Jari Jukkola, Erkki Vihriälä, Outi Kuittinen, Teemu Myllylä, Mika Kaakinen, Vesa Kiviniemi
Publikováno v:
Biophotonics: Photonic Solutions for Better Health Care VI.
Monitoring blood-brain barrier (BBB) opening is of great interest in terms of brain drug delivery in the treatment of brain lymphoma and maybe in the future in other diseases like dementia. A method involving BBB disruption (BBBD) by mannitol infusio