Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jaren Arbanas"'
Autor:
Zheng Yang, James Loy, Brian Poirson, Yanshan Dai, Surendran Rajendran, Shihua Xu, Vanessa Spires, Murali Gururajan, Zheng Lin, Jaren Arbanas, Stephen Carl, Samantha Pace, Yun Wang, John Mehl, Krishna Vasudevan, Thomas Spires, Ruslan Novosiadly, Shodeinde Coker, Raymond Perez, Kelly Covello, Paul Morin, Robert Graziano, Miranda Broz, Lois Lehman-McKeeman
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Pharmacokinetic/pharmacodynamic (PK/PD) modeling was performed to quantitatively integrate preclinical pharmacology and toxicology data for determining the therapeutic index (TI) of an interleukin-10 (IL-10) fragment crystallizable (Fc) fusion protei
Externí odkaz:
https://doaj.org/article/ea7bedd2c46442b79708657bc96f6c3d
Autor:
Ahmed A. Samatar, Lata Jayaraman, Leigh Zawel, Stephen Fawell, Alan Cooper, Anthony Mannarino, Nathaniel L. Elsen, Stuart Black, Priya Dayananth, Clifford R. Restaino, Daniel McMasters, Jaren Arbanas, Gottfried K. Schroeder, My Sam Mansueto, Alan Hruza, Erick J. Morris, Sharda Jha
HTRF and Biacore binding data for active and inactive ERK1 in the presence of SCH772984
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a41d041f5824e4e438c00c030ecb53b
https://doi.org/10.1158/1535-7163.22509012.v1
https://doi.org/10.1158/1535-7163.22509012.v1
Autor:
Ahmed A. Samatar, Lata Jayaraman, Leigh Zawel, Stephen Fawell, Alan Cooper, Anthony Mannarino, Nathaniel L. Elsen, Stuart Black, Priya Dayananth, Clifford R. Restaino, Daniel McMasters, Jaren Arbanas, Gottfried K. Schroeder, My Sam Mansueto, Alan Hruza, Erick J. Morris, Sharda Jha
HTRF and Biacore binding data for active and inactive ERK1 in the presence of SCH772984
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3185945c7ae768bd2e93b8d986a09ade
https://doi.org/10.1158/1535-7163.22508997
https://doi.org/10.1158/1535-7163.22508997
Autor:
Ahmed A. Samatar, Lata Jayaraman, Leigh Zawel, Stephen Fawell, Alan Cooper, Anthony Mannarino, Nathaniel L. Elsen, Stuart Black, Priya Dayananth, Clifford R. Restaino, Daniel McMasters, Jaren Arbanas, Gottfried K. Schroeder, My Sam Mansueto, Alan Hruza, Erick J. Morris, Sharda Jha
Theoretical maximum binding capacity of immobilized ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae21590fd6fe473ad9f65db7f2896fb
https://doi.org/10.1158/1535-7163.22509000.v1
https://doi.org/10.1158/1535-7163.22509000.v1
Autor:
Zheng, Yang, Surendran, Rajendran, Vanessa, Spires, Brian, Poirson, Murali, Gururajan, Zheng, Lin, Jaren, Arbanas, Stanley, Krystek, James, Loy, Yuan, Cheng, Stephen, Carl, Samantha, Pace, Yun, Wang, John, Mehl, Shihua, Xu, Krishna, Vasudevan, Miranda, Broz, Lois, Lehman-McKeeman, Paul, Morin, Robert F, Graziano
Publikováno v:
Drug Metabolism and Disposition. 50:898-908
Fragment crystallizable (Fc) fusion is commonly used for extending the half-life of biotherapeutics such as cytokines. In this work, we studied the pharmacokinetics of Fc-fused interleukin-10 (IL-10) proteins that exhibited potent antitumor activity
Autor:
Sayumi Yamazoe, Srikanth Kotapati, Jason M. Hogan, Sean M. West, Xiaodi A. Deng, SJ Diong, Jaren Arbanas, Thien Anh Nguyen, Aarti Jashnani, Diksha Gupta, Arvind Rajpal, Gavin Dollinger, Pavel Strop
Publikováno v:
Bioconjugate Chemistry. 33:576-585