7T MRI and molecular studies of Dotarem (gadoterate meglumine) retention in macrophages.

Autor: Ahmed Uosef, Arijita Subuddhi, Annie Lu, Henry V. Ubelaker, Christof Karmonik, Jarek Wosik, Rafik M. Ghobrial, Malgorzata Kloc

Publikováno v: Journal of Magnetic Resonance Open, Vol 12, Iss , Pp 100085- (2022)

Gadolinium-based MRI contrast agent Dotarem is commonly used in the clinic. Free Gd3+ is very toxic. Because the crystallographic radius of Gd3+ and Ca2+ is very similar, Gd3+ can compete with Ca2+ in the regulations of cellular functions. Gadolinium

Externí odkaz: https://doaj.org/article/132a4f1e0d9e46dfaadd38988576dc94

RhoA- and Actin-Dependent Functions of Macrophages from the Rodent Cardiac Transplantation Model Perspective -Timing Is the Essence

Autor: Malgorzata Kloc, Ahmed Uosef, Martha Villagran, Robert Zdanowski, Jacek Z. Kubiak, Jarek Wosik, Rafik M. Ghobrial

Publikováno v: Biology, Vol 10, Iss 2, p 70 (2021)

The small GTPase RhoA, and its down-stream effector ROCK kinase, and the interacting Rac1 and mTORC2 pathways, are the principal regulators of the actin cytoskeleton and actin-related functions in all eukaryotic cells, including the immune cells. As

Externí odkaz: https://doaj.org/article/9e4f66451af24b01b7bc1bb536bb08f2

Design maps for the hyperthermic treatment of tumors with superparamagnetic nanoparticles.

Autor: Antonio Cervadoro, Chiara Giverso, Rohit Pande, Subhasis Sarangi, Luigi Preziosi, Jarek Wosik, Audrius Brazdeikis, Paolo Decuzzi

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e57332 (2013)

A plethora of magnetic nanoparticles has been developed and investigated under different alternating magnetic fields (AMF) for the hyperthermic treatment of malignant tissues. Yet, clinical applications of magnetic hyperthermia are sporadic, mostly d

Externí odkaz: https://doaj.org/article/9b3ffd704cf64baa9d3b4402d4c89a10

Hybrid Quantum Systems for Higher Temperature Quantum Information Processing

Autor: John H. Miller, Martha Y. Suárez Villagrán, Johnathan O. Sanderson, Jarek Wosik

Publikováno v: IEEE Transactions on Applied Superconductivity. 33:1-4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df293fdb3f6a0df6ed8f02af432ef973
https://doi.org/10.1109/tasc.2023.3241131

Side effects of gadolinium MRI contrast agents

Autor: Malgorzata Kloc, Jacek Z. Kubiak, Rafik M. Ghobrial, Ahmed Uosef, Jarek Wosik, Martha Villagran

Publikováno v: Pediatria I Medycyna Rodzinna-Paediatrics and Family Medicine
Pediatria I Medycyna Rodzinna-Paediatrics and Family Medicine, 2020, 16 (1), pp.49-52. ⟨10.15557/PiMR.2020.0008⟩

International audience; Magnetic resonance imaging is widely used as a diagnostic tool in the clinic. Magnetic resonance imaging contrast agents such as gadolinium are very often used to improve the quality of images acquired by magnetic resonance im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da3cddf0ef6530f6f1b3a8f7d4807d2
https://doi.org/10.15557/pimr.2020.0008