Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jared S Prisciak"'
Autor:
J. Wilson Quail, Cheryl Santos, Jeremy S. Lee, Jared S Prisciak, Jan Balzarini, Theresa M. Allen, Maniyan P Padmanilyam, Erik De Clercq, Heinz-Bernhard Kraatz, Elias K. Manavathu, Eliud O. Oloo, Gordon A. Zello, Jonathan R. Dimmock, James P. Stables, Arten Cherkasov
Publikováno v:
European Journal of Medicinal Chemistry. 37:813-824
A number of 1,3-arylidene-2-tetralones 1, 2 and 4 were synthesised and demonstrated cytotoxic activity towards murine P388 and L1210 cells as well as human Molt 4/C8 and CEM T-lymphocytes. In general, the related 1-arylidene-2-tetralones 3 possessed
Autor:
Jonathan R. Dimmock, Erik De Clercq, Travis P. Kowalchuk, Narasimhan L. Motaganahalli, Cheryl L. Santos, N. Murthi Kandepu, Renée Leclerc, Uma Pugazhenthi, Jan Balzarini, Theresa M. Allen, J. Wilson Quail, Adil J. Nazarali, Jared S. Prisciak
Publikováno v:
Journal of medicinal chemistry. 43(21)
Five series of novel compounds were synthesized in order to evaluate the theory of sequential cytotoxicity which seeks to exploit the view that various cancer cells are particularly susceptible to successive attacks by cytotoxic agents. The compounds