Výsledky vyhledávání - "Jared R. Patch"

Expanding specificity of class I restricted CD8

Autor: Lasse E, Pedersen, Jared R, Patch, Mary, Kenney, Raisa A, Glabman, Morten, Nielsen, Gregers, Jungersen, Soren, Buus, William T, Golde

Publikováno v: Veterinary immunology and immunopathology. 181

The immune response to the highly acute foot-and-mouth disease virus (FMDV) is routinely reported as a measure of serum antibody. However, a critical effector function of immune responses combating viral infection of mammals is the cytotoxic T lympho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::216dbcc7a73cb55b91c523bf561577dc
https://pubmed.ncbi.nlm.nih.gov/27498407

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Identification of peptides from foot-and-mouth disease virus structural proteins bound by class I swine leukocyte antigen (SLA) alleles, SLA-1*0401 and SLA-2*0401

Autor: Søren Buus, Gregers Jungersen, Morten Nielsen, Lasse Eggers Pedersen, William T. Golde, Jared R. Patch, Mikkel Harndahl

Publikováno v: Animal Genetics. 44:251-258

Summary Characterization of the peptide-binding specificity of swine leukocyte antigen (SLA) class I and II molecules is critical to the understanding of adaptive immune responses of swine toward infectious pathogens. Here, we describe the complete b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6abc26ffe2ea1bebf2c4581452f57c
https://doi.org/10.1111/j.1365-2052.2012.02400.x

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A mature and fusogenic form of the Nipah virus fusion protein requires proteolytic processing by cathepsin L

Autor: Willie Warren Craft, Rebecca Ellis Dutch, Jared R. Patch, Cara T. Pager

Publikováno v: Virology

The Nipah virus fusion (F) protein is proteolytically processed to F1 + F2 subunits. We demonstrate here that cathepsin L is involved in this important maturation event. Cathepsin inhibitors ablated cleavage of Nipah F. Proteolytic processing of Nipa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae531c3090a27b322fb8ce65248d59cb
http://europepmc.org/articles/PMC7111743

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Receptor Binding, Fusion Inhibition, and Induction of Cross-Reactive Neutralizing Antibodies by a Soluble G Glycoprotein of Hendra Virus

Autor: Katharine N. Bossart, Gary Crameri, Lin-Fa Wang, Antony S. Dimitrov, Anil Choudhary, Jared R. Patch, Bryan T. Eaton, Yan-Ru Feng, Bruce A. Mungall, Christopher C. Broder

Publikováno v: Journal of Virology. 79:6690-6702

Hendra virus (HeV) and Nipah virus (NiV) are closely related emerging viruses comprising the Henipavirus genus of the Paramyxovirinae , which are distinguished by their ability to cause fatal disease in both animal and human hosts. These viruses infe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a6be51fa7088a16e8b61d1caf20f08
https://doi.org/10.1128/jvi.79.11.6690-6702.2005

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Infection with foot-and-mouth disease virus (FMDV) induces a natural killer (NK) cell response in cattle that is lacking following vaccination

Autor: Jared R. Patch, William T. Golde, Felix N. Toka, José Barrera, Christopher Schutta, Ryan Waters, Ganesh Kondabattula, Pervaiz Dar

Publikováno v: Comparative immunology, microbiology and infectious diseases. 37(4)

Natural killer (NK) cells play a role in innate antiviral immunity by directly lysing virus-infected cells and producing antiviral cytokines such as interferon gamma (IFN-γ). We developed a system for characterizing the bovine NK response to foot-an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e4dc00093206acccb349b371e71765
https://pubmed.ncbi.nlm.nih.gov/25150134

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Characterization of cytotoxic T lymphocyte function after foot-and-mouth disease virus infection and vaccination

Autor: Juan M. Pacheco, William T. Golde, Jared R. Patch, Mary Kenney, Marvin J. Grubman

Publikováno v: Viral immunology. 26(4)

The induction of neutralizing antibodies specific for foot-and-mouth disease virus (FMDV) has been the central goal of vaccination efforts against this economically important disease of cloven-hoofed animals. Although these efforts have yielded much

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58f86872e2b79eb2c30f359c0e22b72
https://pubmed.ncbi.nlm.nih.gov/23829779

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Induction of foot-and-mouth disease virus-specific cytotoxic T cell killing by vaccination

Autor: Søren Buus, Lasse Eggers Pedersen, Gregers Jungersen, Marvin J. Grubman, Mauro P. Moraes, Jared R. Patch, Morten Nielsen, William T. Golde, Felix N. Toka

Publikováno v: Clinical and vaccine immunology : CVI. 18(2)

Foot-and-mouth disease (FMD) continues to be a significant threat to the health and economic value of livestock species. This acute infection is caused by the highly contagious FMD virus (FMDV), which infects cloven-hoofed animals, including large an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7978c349347ddffd67668ca8e796effc
https://pubmed.ncbi.nlm.nih.gov/21177918

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Mutations in Classical Swine Fever Virus NS4B Affect Virulence in Swine▿

Autor: Ingigerdur Gudmundsdottir, William T. Golde, Vivian O'Donnell, Lauren G. Holinka, Guillermo R. Risatti, M.V. Prarat, Consuelo Carrillo, Douglas P. Gladue, I. Fernandez-Sainz, Jared R. Patch, Z. Lu, Manuel V. Borca, James Zhu

NS4B is one of the nonstructural proteins of classical swine fever virus (CSFV), the etiological agent of a severe, highly lethal disease of swine. Protein domain analysis of the predicted amino acid sequence of the NS4B protein of highly pathogenic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806f92dc3290ec77b8932eefd92074bb
https://europepmc.org/articles/PMC2812325/

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Residues in the Stalk Domain of the Hendra Virus G Glycoprotein Modulate Conformational Changes Associated with Receptor Binding▿

Autor: Katharine N. Bossart, Dimple Khetawat, Dimiter S. Dimitrov, Zhongyu Zhu, Andrew C. Hickey, Kimberly A. Bishop, Jared R. Patch, Lin-Fa Wang, Christopher C. Broder

Hendra virus (HeV) is a member of the broadly tropic and highly pathogenic paramyxovirus genus Henipavirus . HeV is enveloped and infects cells by using membrane-anchored attachment (G) and fusion (F) glycoproteins. G possesses an N-terminal cytoplas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84b161449d3befcf1772bb046982a0a
https://europepmc.org/articles/PMC2573269/

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