Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jared R. Helm"'
Autor:
Lauren Foltz, Ting Wang, Marvin Bentley, Kevin Thorsen, Jared R. Helm, Viola Oorschot, Jesse C. Hay, Judith Klumperman
Publikováno v:
Journal of Biological Chemistry. 289:23609-23628
Luminal calcium released from secretory organelles has been suggested to play a regulatory role in vesicle transport at several steps in the secretory pathway; however, its functional roles and effector pathways have not been elucidated. Here we demo
Autor:
Kevin Thorsen, Jinzhong Zhang, Susan Ferro-Novick, Kevin D. Corbett, Jared R. Helm, Deepali Bhandari, Christopher L. Lord, Shekar Menon, Shuliang Chen, Jesse C. Hay
Publikováno v:
Molecular Biology of the Cell
Previous studies show that the COPII coat is phosphorylated. The phosphorylated coat, however, cannot rebind to the ER to initiate a new round of vesicle budding. The present study shows that Sit4p/PP6, a Ser/Thr phosphatase, dephosphorylates the COP
Autor:
Marvin Bentley, Deborah C. Nycz, Nandhakumar Thayanidhi, Jesse C. Hay, Jared R. Helm, Yingjian Liang
Publikováno v:
Molecular Biology of the Cell
This work demonstrates that α-synuclein inhibits the biosynthetic secretory pathway of mammalian cells potently and directly under nontoxic conditions and in the absence of insoluble α-synuclein aggregates. A potential mechanism involving α-synucl
Publikováno v:
Molecular and Biochemical Parasitology. 159:134-137
Most trypanosomatid genes are transcribed into polycistronic precursor RNAs that are processed into monocistronic mRNAs possessing a 39-nucleotide spliced leader (SL) at their 5'-ends and polyadenylation at their 3'-ends. We show here that precursor
Autor:
Jared R, Helm, Marvin, Bentley, Kevin D, Thorsen, Ting, Wang, Lauren, Foltz, Viola, Oorschot, Judith, Klumperman, Jesse C, Hay
Publikováno v:
The Journal of biological chemistry. 289(34)
Luminal calcium released from secretory organelles has been suggested to play a regulatory role in vesicle transport at several steps in the secretory pathway; however, its functional roles and effector pathways have not been elucidated. Here we demo
Autor:
Maria de Fatima Bonaldo, Mandy Sanders, Marcelo B. Soares, Tatsuya Sakurai, Christiane Hertz-Fowler, John E. Donelson, Michael A. Quail, Matthew Berriman, Jared R. Helm, Noboru Inoue, Martin Aslett
Publikováno v:
Molecular and biochemical parasitology. 168(1)
Trypanosoma congolense is one of the most economically important pathogens of livestock in Africa. Culture-derived parasites of each of the three main insect stages of the T. congolense life cycle, i.e., the procyclic, epimastigote and metacyclic sta
Publikováno v:
Molecular and biochemical parasitology. 163(1)
During their life cycle African trypanosomes must quickly adapt to the different environments of the tsetse fly midgut and the mammalian bloodstream by modulating expression of many of their genes. One group of these differentially expressed genes en