Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jared R Auclair"'
Autor:
Md Amin Hossain, Richa Sarin, Daniel P Donnelly, Brandon C Miller, Alexandra Weiss, Luke McAlary, Svetlana V Antonyuk, Joseph P Salisbury, Jakal Amin, Jeremy B Conway, Samantha S Watson, Jenifer N Winters, Yu Xu, Novera Alam, Rutali R Brahme, Haneyeh Shahbazian, Durgalakshmi Sivasankar, Swathi Padmakumar, Aziza Sattarova, Aparna C Ponmudiyan, Tanvi Gawde, David E Verrill, Wensheng Yang, Sunanda Kannapadi, Leigh D Plant, Jared R Auclair, Lee Makowski, Gregory A Petsko, Dagmar Ringe, Nathalie Y R Agar, David J Greenblatt, Mary Jo Ondrechen, Yunqiu Chen, Justin J Yerbury, Roman Manetsch, S Samar Hasnain, Robert H Brown, Jeffrey N Agar
Publikováno v:
PLoS Biology, Vol 22, Iss 1, p e3002462 (2024)
Mutations in the gene encoding Cu-Zn superoxide dismutase 1 (SOD1) cause a subset of familial amyotrophic lateral sclerosis (fALS) cases. A shared effect of these mutations is that SOD1, which is normally a stable dimer, dissociates into toxic monome
Externí odkaz:
https://doaj.org/article/ae0b075acaa84b09a950667731983ac1
Autor:
Rajesh Kumari, Ji Won Lim, Matthew Ryan Sullivan, Rachel Malampy, Connor Baush, Irina Smolina, Howard Robin, Vadim V. Demidov, Giovanni Stefano Ugolini, Jared R. Auclair, Tania Konry
Publikováno v:
Diagnostics, Vol 12, Iss 9, p 2252 (2022)
SARS-CoV-2 has remained a global health burden, primarily due to the continuous evolution of different mutant strains. These mutations present challenges to the detection of the virus, as the target genes of qPCR, the standard diagnostic method, may
Externí odkaz:
https://doaj.org/article/54e8372ae5da4abc91ca8cb6eb5f2f82
Autor:
Rachael B. Chanin, Kourtney P. Nickerson, Alejandro Llanos-Chea, Jeticia R. Sistrunk, David A. Rasko, Deepak Kumar Vijaya Kumar, John de la Parra, Jared R. Auclair, Jessica Ding, Kelvin Li, Snaha Krishna Dogiparthi, Benjamin J. D. Kusber, Christina S. Faherty
Publikováno v:
mSphere, Vol 4, Iss 6 (2019)
ABSTRACT The Shigella species are Gram-negative, facultative intracellular pathogens that invade the colonic epithelium and cause significant diarrheal disease. Despite extensive research on the pathogen, a comprehensive understanding of how Shigella
Externí odkaz:
https://doaj.org/article/631bf65db92544d0adb3a2bfb6ddb9ea
Autor:
Brittany A Petros, Jacquelyn Turcinovic, Nicole L Welch, Laura F White, Eric D Kolaczyk, Matthew R Bauer, Michael Cleary, Sabrina T Dobbins, Lynn Doucette-Stamm, Mitch Gore, Parvathy Nair, Tien G Nguyen, Scott Rose, Bradford P Taylor, Daniel Tsang, Erik Wendlandt, Michele Hope, Judy T Platt, Karen R Jacobson, Tara Bouton, Seyho Yune, Jared R Auclair, Lena Landaverde, Catherine M Klapperich, Davidson H Hamer, William P Hanage, Bronwyn L MacInnis, Pardis C Sabeti, John H Connor, Michael Springer
Publikováno v:
Clinical Infectious Diseases. 76:e400-e408
Background The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly transmissible in vaccinated and unvaccinated populations. The dynamics that govern its establishment and propensity toward fixation (reaching 100
Autor:
Deirdre L. Slate, Markus Leslloyd Waithe-Alleyne, Kevin Hines, Jared R. Auclair, Rachel Donner, Gyorgy Abel, Troy J. Ganz
Publikováno v:
The Journal of Molecular Diagnostics. 23:1691-1698
Population testing for severe acute respiratory syndrome coronavirus 2 is necessary because of the potential for viral transmission from asymptomatic cases, yet the scarcity of reagents and equipment has increased the cost-prohibitive implementation
Publikováno v:
Naval Research Logistics (NRL). 69:461-483
While biomanufacturing plays a significant role in supporting the economy and ensuring public health, it faces critical challenges, including complexity, high variability, lengthy lead time, and very limited process data, especially for personalized
Autor:
Nicholas P. Pinkhover, Eduardo Sanchez, Kerriann M. Pontbriand, Kenneth Okello, Liam M. Garvey, Kelli P. Fletcher, Alex Pum, Kurvin Li, Gabriel DeOliveira, Teddie Proctor, Jelena D. M. Feenstra, Océane Sorel, Manoj Gandhi, Jared R. Auclair
Genomic surveillance is critical for tracking SARS-CoV-2 Variants of Concern (VOC) and for rapid detection of emerging variants. Whole genome sequencing (WGS) is the predominant method for genomic surveillance; but it is a laborious process for large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aed5d129a2046230b8902203e794b4f6
https://doi.org/10.1101/2022.01.31.22270226
https://doi.org/10.1101/2022.01.31.22270226
Autor:
Brittany A. Petros, Jacquelyn Turcinovic, Nicole L. Welch, Laura F. White, Eric D. Kolaczyk, Matthew R. Bauer, Michael Cleary, Sabrina T. Dobbins, Lynn Doucette-Stamm, Mitch Gore, Parvathy Nair, Tien G. Nguyen, Scott Rose, Bradford P. Taylor, Daniel Tsang, Erik Wendlandt, Michele Hope, Judy T. Platt, Karen R. Jacobson, Tara Bouton, Seyho Yune, Jared R. Auclair, Lena Landaverde, Catherine M. Klapperich, Davidson H. Hamer, William P. Hanage, Bronwyn L. MacInnis, Pardis C. Sabeti, John H. Connor, Michael Springer
The Omicron variant of SARS-CoV-2 is highly transmissible in vaccinated and unvaccinated populations. The dynamics governing its establishment and propensity towards fixation (reaching 100% frequency in the SARS-CoV-2 population) in communities remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c84b881822c67cb791a11737bc456e6
https://doi.org/10.1101/2022.01.27.22269787
https://doi.org/10.1101/2022.01.27.22269787
Autor:
Troy J, Ganz, Rachel, Donner, Kevin M, Hines, Markus L, Waithe-Alleyne, Deirdre L, Slate, Gyorgy, Abel, Jared R, Auclair
Publikováno v:
The Journal of Molecular Diagnostics : JMD
Population testing for severe acute respiratory syndrome coronavirus 2 is necessary because of the potential for viral transmission from asymptomatic cases, yet the scarcity of reagents and equipment has increased the cost-prohibitive implementation
Autor:
Md Amin Hossain, Richa Sarin, Daniel P. Donnelly, Brandon C. Miller, Joseph P. Salisbury, Jeremy B. Conway, Samantha Watson, Jenifer N. Winters, Novera Alam, Durgalakshmi Sivasankar, Aparna C. Ponmudiyan, Tanvi Gawde, Sunanda Kannapadi, Jared R. Auclair, Lee Makowski, Gregory A. Petsko, Dagmar Ringe, David J. Greenblatt, Mary Jo Ondrechen, Yunqiu Chen, Roman Manetsch, Jeffrey N. Agar
Mutations in the gene encoding Cu-Zn superoxide dismutase 1 (SOD1) cause a subset of familial amyotrophic lateral sclerosis (fALS). One effect of these mutations is that SOD1, which is normally a stable dimer, dissociates into toxic monomers. Conside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45dd41470ae6efad78c89e30060826fe
https://doi.org/10.1101/2021.06.23.449516
https://doi.org/10.1101/2021.06.23.449516