Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Jared Q, Gerlach"'
Publikováno v:
Pathogens, Vol 11, Iss 4, p 426 (2022)
Parasitic helminths resort to various mechanisms to evade and modulate their host’s immune response, several of which have been described for Schistosoma mansoni. We recently reported the presence of sialic acid residues on the surface of adult S.
Externí odkaz:
https://doaj.org/article/a0b9312f5b6140fd85401a47f0bda12d
Autor:
Maude Dagenais, Jared Q. Gerlach, George R. Wendt, James J. Collins, Louise E. Atkinson, Angela Mousley, Timothy G. Geary, Thavy Long
Publikováno v:
Pathogens, Vol 10, Iss 11, p 1401 (2021)
Parasitic helminths are master manipulators of host immunity. Their strategy is complex and involves the release of excreted/secreted products, including extracellular vesicles (EVs). The protein and miRNA contents of EVs have been characterised for
Externí odkaz:
https://doaj.org/article/ffca2684a29b4a0a971ca9dc59d227db
Autor:
Marta Utratna, Heidi Annuk, Jared Q. Gerlach, Yuan C. Lee, Marian Kane, Michelle Kilcoyne, Lokesh Joshi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract There is an urgent need for discovery of novel antimicrobials and carbohydrate-based anti-adhesive strategies are desirable as they may not promote resistance. Discovery of novel anti-adhesive molecules from natural product libraries will re
Externí odkaz:
https://doaj.org/article/6508bce32d4b4e14b2c19125fdd3ff0a
Autor:
Eduardo de la Torre-Escudero, Jared Q Gerlach, Adam P S Bennett, Krystyna Cwiklinski, Heather L Jewhurst, Kathryn M Huson, Lokesh Joshi, Michelle Kilcoyne, Sandra O'Neill, John P Dalton, Mark W Robinson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 1, p e0007087 (2019)
Helminth parasites secrete extracellular vesicles (EVs) that can be internalised by host immune cells resulting in modulation of host immunity. While the molecular cargo of EVs have been characterised in many parasites, little is known about the surf
Externí odkaz:
https://doaj.org/article/9bdc6ecfce04429f878cefd3239720d4
Autor:
Kevin Lynch, Oliver Treacy, Jared Q. Gerlach, Heidi Annuk, Paul Lohan, Joana Cabral, Lokesh Joshi, Aideen E. Ryan, Thomas Ritter
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Dendritic cellular therapies and dendritic cell vaccines show promise for the treatment of autoimmune diseases, the prolongation of graft survival in transplantation, and in educating the immune system to fight cancers. Cell surface glycosylation pla
Externí odkaz:
https://doaj.org/article/c051dc13a8074112acb9a9d2ad2a5a0d
Autor:
Joana Cabral, Shirley A. Hanley, Jared Q. Gerlach, Neil O’Leary, Stephen Cunningham, Thomas Ritter, Rhodri Ceredig, Lokesh Joshi, Matthew D. Griffin
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Regulatory T-cells (Treg) are essential for maintaining immune homeostasis and tolerance. Surface glycosylation is ubiquitous on mammalian cells and regulates diverse biological processes. While it is currently well accepted that surface glycan expre
Externí odkaz:
https://doaj.org/article/af50a38afd7a440a8040dbc7099b4c0b
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2460
Half maximal inhibitory concentration (IC
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2460
Mammalian cell surface lectins mediate many important biological interactions which regulate physiological processes and therefore profiling mammalian cells on glycan microarray is of interest. However, many whole mammalian cells are not compatible w
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2460
The use of glycan microarrays to study carbohydrate interactions of bacterial cells is of great interest owing to the key roles these interactions play in bacterial colonization and infection of a host. In this chapter, the methods to fluorescently s
Publikováno v:
Methods in Molecular Biology ISBN: 9781071621479
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6acabb71a56fba3d7ba21c1f60d05650
https://doi.org/10.1007/978-1-0716-2148-6_14
https://doi.org/10.1007/978-1-0716-2148-6_14